Talpa occidentalis (Iberian mole): 119232154
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Entry
119232154 CDS
T07495
Symbol
ABL1
Name
(RefSeq) tyrosine-protein kinase ABL1 isoform X1
KO
K06619
abelson tyrosine-protein kinase 1 [EC:
2.7.10.2
]
Organism
tod
Talpa occidentalis (Iberian mole)
Pathway
tod04012
ErbB signaling pathway
tod04014
Ras signaling pathway
tod04110
Cell cycle
tod04360
Axon guidance
tod04722
Neurotrophin signaling pathway
tod05200
Pathways in cancer
tod05206
MicroRNAs in cancer
tod05208
Chemical carcinogenesis - reactive oxygen species
tod05220
Chronic myeloid leukemia
tod05416
Viral myocarditis
Brite
KEGG Orthology (KO) [BR:
tod00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
119232154 (ABL1)
04014 Ras signaling pathway
119232154 (ABL1)
09140 Cellular Processes
09143 Cell growth and death
04110 Cell cycle
119232154 (ABL1)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
119232154 (ABL1)
09158 Development and regeneration
04360 Axon guidance
119232154 (ABL1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
119232154 (ABL1)
05206 MicroRNAs in cancer
119232154 (ABL1)
05208 Chemical carcinogenesis - reactive oxygen species
119232154 (ABL1)
09162 Cancer: specific types
05220 Chronic myeloid leukemia
119232154 (ABL1)
09166 Cardiovascular disease
05416 Viral myocarditis
119232154 (ABL1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
tod01001
]
119232154 (ABL1)
Enzymes [BR:
tod01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
119232154 (ABL1)
Protein kinases [BR:
tod01001
]
Non-receptor tyrosine kinases
ABL family
119232154 (ABL1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
F_actin_bind
SH2
SH3_1
SH3_2
SH3_9
Haspin_kinase
Kinase-like
SH3_6
ABC1
Motif
Other DBs
NCBI-GeneID:
119232154
NCBI-ProteinID:
XP_037349971
LinkDB
All DBs
Position
Unknown
AA seq
1137 aa
AA seq
DB search
MGQQPGKVLGDQRRPSLPALHFIKGAGKKESSRHGGPHCNVFVEHEALQRPVASDFESQG
LSEAARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCE
AQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQR
SISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRN
KPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVE
EFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLL
YMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKF
PIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERP
EGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGKKGTRGGAGS
LLQAPELPTKTRTSRRAAEHRDTTDMPEAPHSRGAGEPDALDHEPAVSPLLPRKERGLQD
GSVNEDERLLPKDKKTNLFSALIKKKKKTAPAPPKRSSSFREMDGQPERRGAAEDESREV
SNGALALSAPDAAEPARSSKPGGGAGVPNGAFREAGAAGFRSPHLWKKSSTLTGGRLAAG
EEESGSSASKRFLRSCSASCVPHGAGDAEWRSVTLPRGLPSTGRQFDSSTFGGRRSEKPA
LPRKRASENRCDQVARGTVTPPPRLVKKVEEAADEVFKDAAESSPGSSPPSLTPKLHRRQ
AVGAPSSGLPHKDEAGKPGALGTPATSEPAPPTGRAGPGSSGGASKAPTEEPRVRRHKPS
SESPGRDKGKVSKLKPAPPPPPPASGGKAGEAGPGGKAKPTALLVDAASNDAAKASPLGE
AGKKPVPSMPKPLSSTKPAGAPTSPGATPSTAPQAASALAGEQPSSTAFIPLISTRVSLR
KTRQPPERLSSGAITKGVVLDGTEALCLAISRNSEQMASHSAVLEAGKNLYTFCVSYVDS
IQQMRNKFAFREAINKLENNLRELQICPASAGSGPAATQDFSKLLSSVKEISDIVQR
NT seq
3414 nt
NT seq
+upstream
nt +downstream
nt
atggggcagcagcctggaaaagttcttggggaccagaggaggccaagtctgcccgccctg
cacttcatcaaaggagcagggaagaaggagtcgtcgaggcatggggggccgcactgcaat
gtttttgtggagcacgaagcccttcagaggccagtagcgtctgacttcgagtctcaaggt
ctgagcgaagctgctcggtggaactccaaggaaaaccttctcgctggtcctagtgaaaat
gaccccaaccttttcgttgcactgtatgattttgtggccagtggggacaacactctaagc
ataactaaaggtgaaaagctccgggtcttgggctacaatcacaatggcgaatggtgtgaa
gcgcaaaccaaaaatggccaaggctgggtcccaagcaactacatcacgccagtcaacagc
ctggagaagcattcctggtaccacgggcctgtgtcccgcaacgccgccgagtacctgctg
agcagtggcatcaacggcagcttcttggtgcgggagagcgagagcagccccggccagagg
tccatctcgctgagatacgaaggcagggtgtaccactacaggatcaacactgcttccgat
ggcaagctgtacgtctcttcggagagccgcttcaacacgctggccgagctggtgcaccac
cattccacagtggccgacgggctcatcaccaccctccactacccggcccccaagcgcaac
aagcccacggtctatggcgtgtcccccaactacgacaagtgggaaatggagcgcacggac
atcaccatgaagcacaagctgggaggaggccagtacggggaagtgtacgagggcgtgtgg
aagaagtacagcctgacagtggccgtgaagaccttgaaggaggacaccatggaggtggaa
gagtttttgaaagaagctgcagtaatgaaagagatcaagcaccctaacctggtgcagctc
ctcggggtctgcacccgggagccccccttctacataatcactgagttcatgacctatggg
aacctgttggattacctgcgagagtgtaaccggcaggaggtgaatgcggtggtgctgctt
tacatggccactcagatctcgtccgccatggagtacctggagaagaaaaacttcatccac
agagacctggctgcccggaactgcctggtaggggaaaaccacttggtaaaggtggcggat
ttcggcctgagcaggttaatgacgggggacacgtacacagcccatgccggggccaagttc
cccatcaagtggaccgcgcccgagagcctggcctacaacaagttctccatcaagtccgac
gtctgggcgtttggagtattgctctgggaaattgctacctacggcatgtcaccttaccct
gggattgacctgtcccaggtgtatgagctgctggagaaggactatcgcatggagcgcccc
gaaggctgcccagagaaggtctacgagctcatgcgcgcatgttggcagtggaacccctca
gaccggccctccttcgcagagatccaccaagcctttgagacgatgttccaggagtccagc
atatccgatgaagtggagaaggagctggggaagaagggcacgcgcggcggcgcaggctcc
ttgctgcaggctcccgagctgcccaccaagaccagaacctccagaagagcggcggagcac
agagacaccaccgacatgcccgaggcaccccactccaggggggcgggagagcctgatgct
ctggaccacgagcccgctgtgtctccgttgctccctcgaaaagagcggggtctgcaggac
ggcagtgtgaacgaagacgagcgccttctcccgaaagacaagaagaccaacttgttcagc
gccctgatcaagaagaagaagaaaaccgctccggcccctcccaaacgcagcagctccttc
cgggagatggacggccagcccgagcgcaggggcgccgccgaggacgagagccgagaggtc
agcaacggggcgctggcgctttcagccccggacgcggccgagccggccaggtcctccaag
cccggcggcggggccggcgtccccaatggcgccttccgggaggcaggggctgcgggcttc
cggtctcctcacctgtggaaaaagtccagcaccctgaccggcggccggttagcggccgga
gaggaggagagtggcagcagtgccagcaagcgcttcctgaggtcctgctccgcctcctgc
gtgccccacggggccggcgacgccgagtggaggtcggtcacgctgccccggggcctgccg
tccacgggaaggcagtttgactcgtccacgtttggagggcgcagaagcgagaagccggct
ctgccgaggaagcgggcaagtgagaacaggtgtgaccaggtggccagaggcacggtcacc
cccccgcccaggttggtgaagaaggtggaggaagcagctgacgaggtcttcaaggacgcg
gcagagtccagcccgggctccagcccccccagcctgactccaaagctgcaccgcaggcag
gccgtgggggcgccttcctccggccttccccacaaggacgaggccgggaagccaggggcc
ttggggacacccgccacctccgagccggcaccccccaccggcagggcagggccaggctct
tctgggggagccagcaaggcccccaccgaggagcccagggtgaggaggcacaagccctct
tccgagtcccctggaagagacaaggggaaggtgtccaagctcaagcctgcccccccgccc
cccccaccagcctcggggggcaaagccggggaggccggccccggcgggaaggccaagccc
accgccctgcttgtggatgcggcgagcaacgatgccgccaaagccagcccactgggagag
gccggcaaaaagcctgtcccgtccatgccaaagccactgtcgtccaccaagccggcgggg
gcccccaccagcccgggcgccactccctccacggcgccccaggccgcctctgccctggca
ggggagcagccgtcctccaccgccttcatcccgctcatatccacccgcgtgtctctccgg
aaaacccggcagcccccggagcggctcagcagcggggccatcaccaagggcgtggtcctg
gacggcaccgaggccctgtgcctcgccatctccaggaactccgagcagatggccagccac
agcgccgtgctggaggccggcaagaacctctacacgttctgcgtgagctacgtggactcc
atccagcaaatgaggaacaaattcgccttccgggaggccatcaacaaactggagaataac
ctccgggagcttcagatctgcccggcgagcgcggggagtggcccagcggctactcaggac
ttcagcaaactcctcagctctgtgaaagagatcagtgacatcgtccagaggtag
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