KEGG   Talpa occidentalis (Iberian mole): 119232800
Entry
119232800         CDS       T07495                                 
Symbol
TGFBR1
Name
(RefSeq) TGF-beta receptor type-1 isoform X1
  KO
K04674  TGF-beta receptor type-1 [EC:2.7.11.30]
Organism
tod  Talpa occidentalis (Iberian mole)
Pathway
tod04010  MAPK signaling pathway
tod04060  Cytokine-cytokine receptor interaction
tod04068  FoxO signaling pathway
tod04144  Endocytosis
tod04218  Cellular senescence
tod04350  TGF-beta signaling pathway
tod04371  Apelin signaling pathway
tod04380  Osteoclast differentiation
tod04390  Hippo signaling pathway
tod04520  Adherens junction
tod04659  Th17 cell differentiation
tod04926  Relaxin signaling pathway
tod04933  AGE-RAGE signaling pathway in diabetic complications
tod05142  Chagas disease
tod05161  Hepatitis B
tod05166  Human T-cell leukemia virus 1 infection
tod05200  Pathways in cancer
tod05210  Colorectal cancer
tod05212  Pancreatic cancer
tod05220  Chronic myeloid leukemia
tod05225  Hepatocellular carcinoma
tod05226  Gastric cancer
tod05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:tod00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    119232800 (TGFBR1)
   04350 TGF-beta signaling pathway
    119232800 (TGFBR1)
   04390 Hippo signaling pathway
    119232800 (TGFBR1)
   04371 Apelin signaling pathway
    119232800 (TGFBR1)
   04068 FoxO signaling pathway
    119232800 (TGFBR1)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    119232800 (TGFBR1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    119232800 (TGFBR1)
  09143 Cell growth and death
   04218 Cellular senescence
    119232800 (TGFBR1)
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    119232800 (TGFBR1)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    119232800 (TGFBR1)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    119232800 (TGFBR1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    119232800 (TGFBR1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    119232800 (TGFBR1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    119232800 (TGFBR1)
   05212 Pancreatic cancer
    119232800 (TGFBR1)
   05225 Hepatocellular carcinoma
    119232800 (TGFBR1)
   05226 Gastric cancer
    119232800 (TGFBR1)
   05220 Chronic myeloid leukemia
    119232800 (TGFBR1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    119232800 (TGFBR1)
   05161 Hepatitis B
    119232800 (TGFBR1)
  09174 Infectious disease: parasitic
   05142 Chagas disease
    119232800 (TGFBR1)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    119232800 (TGFBR1)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    119232800 (TGFBR1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:tod01001]
    119232800 (TGFBR1)
Enzymes [BR:tod01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.30  receptor protein serine/threonine kinase
     119232800 (TGFBR1)
Protein kinases [BR:tod01001]
 Receptor serine/threonine kinases (RSTK): TKL group
  TGFBR1 family [OT]
   119232800 (TGFBR1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr TGF_beta_GS Activin_recp Pkinase_fungal APH Haspin_kinase FTA2
Other DBs
NCBI-GeneID: 119232800
NCBI-ProteinID: XP_037350954
LinkDB
Position
Unknown
AA seq 438 aa
MCIAEIDLIPRDRPFVCAPSSKTGSVTTTYCCNQDHCNKIELPPVGRFLGKPPSGLGPVE
LAAVIAGPVCFVCISLMLMVYICHNRTVIHHRVPNEEDPSLDRPFISEGTTLKDLIYDMT
TSGSGSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFRE
AEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKL
ALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTI
DIAPNHRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQ
LPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTA
LRIKKTLSQLSQQEGIKM
NT seq 1317 nt   +upstreamnt  +downstreamnt
atgtgtatagctgaaattgatctgattcctcgagacaggccctttgtatgtgcaccatct
tcaaaaactgggtctgtaactacaacatattgctgcaatcaggaccactgcaataaaata
gaactcccacctgttggtcgttttctaggaaagccaccatctggccttggtcctgtggaa
ctggctgctgtcattgctggaccagtctgttttgtgtgcatctcactcatgttgatggtc
tatatctgccataaccgtactgtcattcaccatcgcgtgcccaacgaagaggatccttca
ttagaccgtcctttcatttcagagggcacaacgttaaaagatttaatttatgacatgaca
acatcagggtctggatcaggtttaccattgcttgttcaaagaacaattgcaagaactatt
gtgttacaagaaagcattggcaaaggtcgatttggagaagtttggagaggaaagtggaga
ggagaagaagttgctgttaaaatcttttcttctagagaagaacgttcatggttccgtgag
gcagagatttatcaaactgtaatgttacgtcatgaaaacatcttgggatttatagcggca
gacaataaagacaatggtacatggactcagctctggttggtgtcagattaccatgaacat
ggatccctttttgattatttgaacagatacacagttactgtggaaggaatgataaaactt
gctctgtccacagcaagtggacttgcccatcttcacatggagattgttggtacccaagga
aagccagccattgctcatagagatttgaaatcaaagaatatcttggtaaagaagaatgga
acttgctgtattgcagacttgggactggcagtaagacatgattcggccacagatacaatt
gatattgctccaaaccacagagtgggaacaaaaaggtacatggcccctgaagttctagat
gattccataaatatgaaacactttgagtccttcaaacgtgccgacatctatgcaatgggc
ttagtgttctgggaaatagctcgacgatgttccattggtggaattcatgaagattaccag
ctgccttattatgatcttgtaccttctgacccatcagttgaagaaatgagaaaagttgtt
tgtgaacagaagttaaggcctaatattccaaacagatggcagagctgtgaagccttaaga
gtaatggctaaaattatgagagaatgttggtatgccaatggagccgctagacttacagct
ttgcggattaagaaaacattgtcacaactcagtcagcaggaaggcatcaaaatgtaa

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