Talpa occidentalis (Iberian mole): 119232808
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Entry
119232808 CDS
T07495
Symbol
GNE
Name
(RefSeq) bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase isoform X2
KO
K12409
bifunctional UDP-N-acetylglucosamine 2-epimerase / N-acetylmannosamine kinase [EC:
3.2.1.183
2.7.1.60
]
Organism
tod
Talpa occidentalis (Iberian mole)
Pathway
tod00520
Amino sugar and nucleotide sugar metabolism
tod00541
Biosynthesis of various nucleotide sugars
tod01100
Metabolic pathways
tod01250
Biosynthesis of nucleotide sugars
Module
tod_M00955
CMP-Neu5Ac/Neu5Gc biosynthesis, animals, UDP-GlcNAc => CMP-Neu5Ac => CMP-Neu5Gc
Brite
KEGG Orthology (KO) [BR:
tod00001
]
09100 Metabolism
09107 Glycan biosynthesis and metabolism
00520 Amino sugar and nucleotide sugar metabolism
119232808 (GNE)
00541 Biosynthesis of various nucleotide sugars
119232808 (GNE)
Enzymes [BR:
tod01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.60 N-acylmannosamine kinase
119232808 (GNE)
3. Hydrolases
3.2 Glycosylases
3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
3.2.1.183 UDP-N-acetylglucosamine 2-epimerase (hydrolysing)
119232808 (GNE)
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Ortholog
Paralog
GFIT
Motif
Pfam:
Epimerase_2
ROK
Hexokinase_1
FGGY_N
DRTGG
Glucokinase
Motif
Other DBs
NCBI-GeneID:
119232808
NCBI-ProteinID:
XP_037350977
LinkDB
All DBs
Position
Unknown
AA seq
722 aa
AA seq
DB search
MEKNGNNRKLRVCVATCNRADYSKLAPIMFGIKTEPEFFELDVVVLGSHLIDDYGNTYRM
IEQDDFDINTRLHTIVRGEDEAAMVESVGLALVKLPDVLNRLKPDIMIVHGDRFDALALA
TSAALMNIRILHIEGGEVSGTIDDSIRHAITKLAHYHVCCTRSAEQHLISMCEDHDRILL
AGCPSYDKLLSAKNKDYMSIIRMWLGDDVKSKDYIVALQHPVTTDIKHSIKMFELTLDAL
ISFNKRTLILFPNIDAGSKEMVRVMRKKGIEHHPNFRAVKHVPFDQFIQLVAHAGCMIGN
SSCGVREVGAFGTPVINLGTRQIGRETGENVLHVRDADTKDKILQALQLQFGKQYPCSKI
YGDGNAVPRILKFLKSIDLQEPLQKKFCFPPVKDNISQDIDHILETLSALAVDLGGTNLR
VAIVSMKGEIVKKYTQFNPKTYEERINLILQMCVEAAAEAVKLNCRILGVGISTGGRVNP
REGIVLHSTKLIQEWNSVDLRTPLSDNLHLPVWVDNDGNCAALAERKFGQGKGLENFVTL
ITGTGIGGGIIHQHELIHGSSFCAAELGHLVVSLDGPDCSCGSHGCIEAYASGMALQREA
KKLHDEDLLLVEGMSVPKDEAVGALHLIQAAKLGNVKAQSILRTAGTALGLGVVNILHTM
NPSLVILSGVLASHYIHIVKDVIRQQALPSVQDVDVVASDLADPALLGAASMVLDYTTRR
VY
NT seq
2169 nt
NT seq
+upstream
nt +downstream
nt
atggagaagaacgggaataaccgaaaacttcgagtttgcgttgcgacttgcaaccgtgct
gattattcaaaacttgccccaatcatgtttggaattaaaacggaacctgagttctttgaa
cttgatgtggtggtacttggctctcacctgatagatgactatggaaacacatatcgcatg
attgaacaagatgactttgacattaacaccaggctacacacaattgttagaggggaagat
gaggcagccatggtggagtcagtgggcctggccctagtgaagctaccagatgtgctcaat
cgcctgaagcctgatatcatgattgttcatggagacaggtttgacgccctggctctggct
acatctgctgccttaatgaacatccgaatccttcacattgaaggtggggaagtcagtggg
accattgatgactctatcagacatgccatcacaaaactggctcattatcatgtgtgctgc
actcgaagtgcagagcaacacctaatatccatgtgtgaggaccatgatcgcatccttctg
gcaggctgcccttcctatgataaacttctctctgctaagaacaaagactacatgagcatc
attcgcatgtggttaggtgatgatgtaaaatctaaagattacattgttgcactacagcac
cctgtgaccactgatattaagcattccataaaaatgtttgaacttacattggatgcactt
atctcatttaacaagcggactctaattctgtttccaaatattgatgcagggagcaaagag
atggttcgagtgatgcggaaaaagggcattgagcatcatcccaattttcgtgcagttaag
catgttccatttgaccagtttatacagttggttgcccatgctggttgtatgattgggaat
agcagctgtggggtacgcgaggttggagcttttggaacacctgtgatcaacctaggaaca
cgtcagattggaagagaaacaggggagaatgttcttcatgttcgggatgctgatactaaa
gacaaaatattgcaagcactacaacttcagtttggtaaacaatatccttgttcaaagata
tatggggatggaaatgctgttccaagaattttgaaatttctcaaatctattgatcttcaa
gagccattacaaaagaaattctgctttcctcctgtgaaggataacatttctcaagatatt
gaccacattcttgaaactttgagtgccttggctgttgatctcggcgggacgaacctccga
gttgcaatagttagcatgaagggtgaaatagttaagaagtatactcagttcaatcctaaa
acctatgaagaaaggattaatttgatcctgcagatgtgtgtcgaagctgcagcagaagct
gtaaaattgaattgcagaattttgggtgtaggcatttccactggtggccgtgtgaatcct
cgagaaggaattgtgttacattcaaccaaactgattcaagaatggaactctgtagacctt
agaactcccctatctgacaatttgcatctccctgtgtgggtagacaatgatggcaactgt
gctgccctggcagaaaggaaatttggccaaggaaagggtctggaaaactttgtgacactg
atcacaggcacaggaattggcggtgggatcatccatcagcacgaactgatccatggaagc
tccttctgtgcggcagaacttggccaccttgttgtgtccctggatgggcctgattgttcc
tgtggaagccatggctgtattgaagcctatgcctctggaatggccttgcagagagaagca
aaaaaactacatgatgaagacctgctcttggtggaagggatgtcagtgccaaaagatgaa
gccgtgggtgccctccatcttatccaagcggcaaaactcggcaatgtgaaggcccagagc
atcttgagaacagctggaacagctttgggccttggggttgtgaacatcctgcataccatg
aacccttccctggtcatcctgtctggagtccttgccagccactatattcacattgtcaag
gatgtcatccgccagcaagccctcccgtctgtccaggacgtggacgtggtggcctcggat
ctggctgatcccgccctccttggtgccgccagcatggttctggactacacaacccgcagg
gtctactag
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