Talpa occidentalis (Iberian mole): 119232956
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Entry
119232956 CDS
T07495
Symbol
FPGS
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial isoform X1
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
tod
Talpa occidentalis (Iberian mole)
Pathway
tod00790
Folate biosynthesis
tod01100
Metabolic pathways
tod01240
Biosynthesis of cofactors
tod01523
Antifolate resistance
tod04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
tod00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
119232956 (FPGS)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
119232956 (FPGS)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
119232956 (FPGS)
Enzymes [BR:
tod01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
119232956 (FPGS)
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Ortholog
Paralog
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
119232956
NCBI-ProteinID:
XP_037351235
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All DBs
Position
Unknown
AA seq
588 aa
AA seq
DB search
MSRAHGHLRAALSLAAVSARGATSRGAARRGLSARPAPQEPGMEYQEAVRTLNTLQTNAG
YLEQAKRQRGDPQTQLEAMEQYLARSGLQVEDLDQLNIIHVTGTKGKGSTCAFTERILRS
YGLKTGFFSSPHLVQVRERIRINGQPISPELFTKHFWHLYQRLEETKGDSSCVSMPAYFR
FLTLMAFHVFLQEKVDLAVVEVGIGGAYDCTNIVRRPVVCGVSSLGIDHTSLLGDTIEKI
AWQKGGIFKPGVPAFTVLQPDSPLAVLRDRAQQVSCPLYLCPPLEALEEGGLPLTLGLEG
EHQRSNAALALQLARCWLKLRNHQGIGELKASFRQSHAGQLPLAPVFQPTSHMQHGLRDT
DWPGRTQVLRRGPLTWYLDGAHTSSSVQACVRWFRQALQGLRPSGGPEVRVLLFNSTGDR
DSAALLKLLQPCQFDFAVFCPNLTEVSLAGNADQQNFTVTLDQVLLRCLEHQQHWSRLDE
EQADLDLWSTPSPELGGPAPLRLAPRPPHPHSTNSLVFSCISHALQWISQGRDPVFQPPG
PPRGLLSHPVADSGASVLREAAAIQVLVTGSLHLVGGVLKLLEPSLSQ
NT seq
1767 nt
NT seq
+upstream
nt +downstream
nt
atgtcgcgcgcccacggccacctgcgcgcggcgctgagcctggcggccgtttctgcgcgc
ggcgcgacgtcccggggcgcggcgcggcgagggttgagcgcgcggcccgcgccgcaagag
ccaggcatggagtatcaggaggctgtgcgcacactcaacaccctgcagaccaatgctggc
tacctagagcaggcgaagcgccagcggggtgacccccagacacagctggaagccatggag
cagtatttggcacggagtgggctgcaggtggaagatttggaccagctgaacatcatccac
gtcactgggaccaaggggaagggctccacctgtgccttcactgaacggatcctccgaagc
tatggcctgaagacaggattctttagctctccccacctggtgcaggtgcgtgagcgaatc
cgcatcaacgggcagcccatcagccccgagctcttcaccaagcacttctggcacctctac
caacgactggaggagaccaagggtgacagcagctgtgtctccatgcctgcctacttccgc
ttcctcacgctcatggccttccatgtcttcctccaagagaaggtggacctggcagtggtg
gaggtgggtataggcggtgcctatgactgcaccaacatcgtcaggaggcctgtggtgtgc
ggggtctcctctctcggcattgaccacaccagccttctgggggacacgatagagaagatc
gcgtggcagaaagggggcatcttcaagcctggcgtccccgccttcaccgtgctccagcct
gacagtcccctggccgtgctgagggaccgagcccagcaggtctcgtgtcctctctacctg
tgcccaccgttggaagccctggaggaaggggggttgcccctgaccctgggcctggaggga
gagcaccagcggtccaatgctgccttggccttgcagttggctcgctgttggctgaagctg
cggaaccaccagggcattggggagctgaaggcatcattcaggcagagccacgcagggcaa
ctgcccctggcacctgtgttccagcccacgtcccacatgcagcacgggcttcgggacacg
gattggcctggccggacgcaggtgctgcggcgcgggccgctcacctggtacctggacggc
gcgcacacctccagcagcgtgcaggcctgtgtgcgctggttccgccaggcgctgcaaggc
ctgcggccgagcggcggacctgaggtgcgtgtcttgctcttcaactccaccggggaccgg
gattccgccgccctgctgaagctgctgcagccctgccagtttgactttgctgttttctgc
cctaacctgacagaggtgtccttggctggcaatgcagatcagcagaacttcacagtgacg
ctggaccaagtgctgctccgctgtctggaacaccagcagcactggagccgcctggatgag
gagcaggctgacctggatctctggagcacccccagtccagagctagggggacctgcgccc
ctgcgcctggcaccccgcccaccccacccccatagcaccaactccctcgtcttcagctgc
atctcccatgccttacagtggatcagccaaggccgggaccccgtctttcagccacctggt
cccccgaggggcctcctgtcccaccctgtggcagacagtggggccagcgtgctccgggag
gcggcggccatccaggtgctggtcaccgggagcctgcacctggtgggcggtgtcctgaag
ctgctggagccctccctgtcccagtag
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