Talpa occidentalis (Iberian mole): 119233001
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Entry
119233001 CDS
T07495
Symbol
SRC
Name
(RefSeq) proto-oncogene tyrosine-protein kinase Src
KO
K05704
tyrosine-protein kinase Src [EC:
2.7.10.2
]
Organism
tod
Talpa occidentalis (Iberian mole)
Pathway
tod01521
EGFR tyrosine kinase inhibitor resistance
tod01522
Endocrine resistance
tod04012
ErbB signaling pathway
tod04015
Rap1 signaling pathway
tod04062
Chemokine signaling pathway
tod04081
Hormone signaling
tod04137
Mitophagy - animal
tod04144
Endocytosis
tod04360
Axon guidance
tod04370
VEGF signaling pathway
tod04510
Focal adhesion
tod04520
Adherens junction
tod04530
Tight junction
tod04540
Gap junction
tod04611
Platelet activation
tod04613
Neutrophil extracellular trap formation
tod04625
C-type lectin receptor signaling pathway
tod04727
GABAergic synapse
tod04750
Inflammatory mediator regulation of TRP channels
tod04810
Regulation of actin cytoskeleton
tod04912
GnRH signaling pathway
tod04915
Estrogen signaling pathway
tod04917
Prolactin signaling pathway
tod04919
Thyroid hormone signaling pathway
tod04921
Oxytocin signaling pathway
tod04926
Relaxin signaling pathway
tod05100
Bacterial invasion of epithelial cells
tod05135
Yersinia infection
tod05152
Tuberculosis
tod05161
Hepatitis B
tod05163
Human cytomegalovirus infection
tod05167
Kaposi sarcoma-associated herpesvirus infection
tod05168
Herpes simplex virus 1 infection
tod05203
Viral carcinogenesis
tod05205
Proteoglycans in cancer
tod05207
Chemical carcinogenesis - receptor activation
tod05208
Chemical carcinogenesis - reactive oxygen species
tod05219
Bladder cancer
tod05417
Lipid and atherosclerosis
tod05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
tod00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
119233001 (SRC)
04015 Rap1 signaling pathway
119233001 (SRC)
04370 VEGF signaling pathway
119233001 (SRC)
09133 Signaling molecules and interaction
04081 Hormone signaling
119233001 (SRC)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
119233001 (SRC)
04137 Mitophagy - animal
119233001 (SRC)
09144 Cellular community - eukaryotes
04510 Focal adhesion
119233001 (SRC)
04520 Adherens junction
119233001 (SRC)
04530 Tight junction
119233001 (SRC)
04540 Gap junction
119233001 (SRC)
09142 Cell motility
04810 Regulation of actin cytoskeleton
119233001 (SRC)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
119233001 (SRC)
04613 Neutrophil extracellular trap formation
119233001 (SRC)
04625 C-type lectin receptor signaling pathway
119233001 (SRC)
04062 Chemokine signaling pathway
119233001 (SRC)
09152 Endocrine system
04912 GnRH signaling pathway
119233001 (SRC)
04915 Estrogen signaling pathway
119233001 (SRC)
04917 Prolactin signaling pathway
119233001 (SRC)
04921 Oxytocin signaling pathway
119233001 (SRC)
04926 Relaxin signaling pathway
119233001 (SRC)
04919 Thyroid hormone signaling pathway
119233001 (SRC)
09156 Nervous system
04727 GABAergic synapse
119233001 (SRC)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
119233001 (SRC)
09158 Development and regeneration
04360 Axon guidance
119233001 (SRC)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
119233001 (SRC)
05207 Chemical carcinogenesis - receptor activation
119233001 (SRC)
05208 Chemical carcinogenesis - reactive oxygen species
119233001 (SRC)
05203 Viral carcinogenesis
119233001 (SRC)
09162 Cancer: specific types
05219 Bladder cancer
119233001 (SRC)
09172 Infectious disease: viral
05161 Hepatitis B
119233001 (SRC)
05168 Herpes simplex virus 1 infection
119233001 (SRC)
05163 Human cytomegalovirus infection
119233001 (SRC)
05167 Kaposi sarcoma-associated herpesvirus infection
119233001 (SRC)
09171 Infectious disease: bacterial
05135 Yersinia infection
119233001 (SRC)
05152 Tuberculosis
119233001 (SRC)
05100 Bacterial invasion of epithelial cells
119233001 (SRC)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
119233001 (SRC)
05418 Fluid shear stress and atherosclerosis
119233001 (SRC)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
119233001 (SRC)
01522 Endocrine resistance
119233001 (SRC)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
tod01001
]
119233001 (SRC)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
tod04131
]
119233001 (SRC)
Enzymes [BR:
tod01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
119233001 (SRC)
Protein kinases [BR:
tod01001
]
Non-receptor tyrosine kinases
SRC family
119233001 (SRC)
Membrane trafficking [BR:
tod04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
119233001 (SRC)
Endocytosis
Clathrin-mediated endocytosis
Kinases
119233001 (SRC)
Lipid raft mediated endocytosis
Caveolin-mediated endocytosis
119233001 (SRC)
Macropinocytosis
Kinases
119233001 (SRC)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2
SH3_1
SH3_9
SH3_2
SH2_1
DUF7063
SH3_10
ABC1
Haspin_kinase
SH3_3
Motif
Other DBs
NCBI-GeneID:
119233001
NCBI-ProteinID:
XP_037351292
LinkDB
All DBs
Position
Unknown
AA seq
536 aa
AA seq
DB search
MGSNKSKPKDASQRRRSLEPAENAHGGGGGAFPTSQTPSKPASADGHRGPSTAFSPAAAE
PKLFGGFNSSDTVTSPQRTGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTEGD
WWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRES
ETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFSSLQQLVAYYSKHADGL
CHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTL
KPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGETGKY
LRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYT
ARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVER
GYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL
NT seq
1611 nt
NT seq
+upstream
nt +downstream
nt
atgggcagcaacaagagcaagcccaaggatgccagccagcggcgccgcagcctggagcct
gccgagaatgcccatggaggtggcgggggtgcctttcccacctcacagacccccagcaag
ccggcctctgccgatggccaccgcggccccagcacagccttctcccctgcggctgctgag
cccaagctcttcggaggcttcaactcctcggacacagtcacctccccacagaggacagga
cctctggctggtggagtgaccacctttgtggccctctatgactatgagtcgaggacagag
actgacctgtccttcaagaaaggggagcggctccagattgtcaacaacacagagggagac
tggtggctggcccactcgctcagcacaggacagacgggttacatccccagcaactatgtg
gcaccttcagactccatccaggctgaggagtggtactttggcaagattaccagacgggag
tcagagcggttactgctcaatgcggagaatccaagagggaccttcctagttcgagaaagc
gagaccacgaaaggtgcctactgcctctcagtgtccgacttcgacaacgccaagggtctc
aatgtgaagcactacaagatccgcaagctcgacagcgggggcttctacatcacctcccgc
acccagttcagcagtctgcagcagctggtggcctactactccaagcatgccgacggcctg
tgccaccgcctcaccactgtgtgccccacgtccaagccacagactcagggcctggccaag
gatgcctgggagatcccccgggagtcgctgcggctggaggtcaagctgggccagggctgc
tttggagaggtgtggatgggcacctggaacggcaccaccagggtggccatcaaaaccctg
aagccaggcacgatgtctccagaggccttcctgcaggaggcccaggtcatgaagaaactg
aggcacgagaagctggtgcagctgtatgcggtggtgtctgaggaacccatctacatcgtc
acggagtacatgagcaaggggagtttgctggattttctcaagggggagacgggcaagtac
ttgcggctgcctcagctggtggacatggctgctcagatcgcctcgggcatggcatatgtg
gagcgaatgaactacgtgcaccgggacctccgtgcagccaacatcctggttggagagaac
ctggtgtgcaaagtggctgactttgggctggcccggctcatcgaagacaacgagtacaca
gcccggcaaggtgccaaattccccatcaagtggacagctccagaagctgccctctacggc
cggttcaccatcaagtcagacgtgtggtcctttgggatcctgctgacggagctcaccaca
aagggacgggtgccctaccctgggatggtgaatcgtgaggtgctggaccaggtggagcgg
ggctaccggatgccctgcccgccggagtgtcccgagtccttgcacgacctcatgtgccag
tgctggcggaaggagcctgaggagaggcccacctttgagtacctgcaggccttcctggag
gactacttcacgtctaccgaaccccagtaccagcccggagagaacctatag
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