Talpa occidentalis (Iberian mole): 119234060
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Entry
119234060 CDS
T07495
Symbol
CACNA1S
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1S
KO
K04857
voltage-dependent calcium channel L type alpha-1S
Organism
tod
Talpa occidentalis (Iberian mole)
Pathway
tod04010
MAPK signaling pathway
tod04020
Calcium signaling pathway
tod04022
cGMP-PKG signaling pathway
tod04024
cAMP signaling pathway
tod04260
Cardiac muscle contraction
tod04261
Adrenergic signaling in cardiomyocytes
tod04270
Vascular smooth muscle contraction
tod04723
Retrograde endocannabinoid signaling
tod04725
Cholinergic synapse
tod04726
Serotonergic synapse
tod04727
GABAergic synapse
tod04911
Insulin secretion
tod04912
GnRH signaling pathway
tod04921
Oxytocin signaling pathway
tod04924
Renin secretion
tod04925
Aldosterone synthesis and secretion
tod04927
Cortisol synthesis and secretion
tod04929
GnRH secretion
tod04934
Cushing syndrome
tod04935
Growth hormone synthesis, secretion and action
tod05010
Alzheimer disease
tod05020
Prion disease
tod05022
Pathways of neurodegeneration - multiple diseases
tod05207
Chemical carcinogenesis - receptor activation
tod05410
Hypertrophic cardiomyopathy
tod05412
Arrhythmogenic right ventricular cardiomyopathy
tod05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
tod00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
119234060 (CACNA1S)
04020 Calcium signaling pathway
119234060 (CACNA1S)
04024 cAMP signaling pathway
119234060 (CACNA1S)
04022 cGMP-PKG signaling pathway
119234060 (CACNA1S)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
119234060 (CACNA1S)
04929 GnRH secretion
119234060 (CACNA1S)
04912 GnRH signaling pathway
119234060 (CACNA1S)
04921 Oxytocin signaling pathway
119234060 (CACNA1S)
04935 Growth hormone synthesis, secretion and action
119234060 (CACNA1S)
04924 Renin secretion
119234060 (CACNA1S)
04925 Aldosterone synthesis and secretion
119234060 (CACNA1S)
04927 Cortisol synthesis and secretion
119234060 (CACNA1S)
09153 Circulatory system
04260 Cardiac muscle contraction
119234060 (CACNA1S)
04261 Adrenergic signaling in cardiomyocytes
119234060 (CACNA1S)
04270 Vascular smooth muscle contraction
119234060 (CACNA1S)
09156 Nervous system
04727 GABAergic synapse
119234060 (CACNA1S)
04725 Cholinergic synapse
119234060 (CACNA1S)
04726 Serotonergic synapse
119234060 (CACNA1S)
04723 Retrograde endocannabinoid signaling
119234060 (CACNA1S)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
119234060 (CACNA1S)
09164 Neurodegenerative disease
05010 Alzheimer disease
119234060 (CACNA1S)
05020 Prion disease
119234060 (CACNA1S)
05022 Pathways of neurodegeneration - multiple diseases
119234060 (CACNA1S)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
119234060 (CACNA1S)
05412 Arrhythmogenic right ventricular cardiomyopathy
119234060 (CACNA1S)
05414 Dilated cardiomyopathy
119234060 (CACNA1S)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
119234060 (CACNA1S)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
tod04040
]
119234060 (CACNA1S)
Ion channels [BR:
tod04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
119234060 (CACNA1S)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Ion_trans
GPHH
Ca_chan_IQ
PKD_channel
CAC1F_C
Motif
Other DBs
NCBI-GeneID:
119234060
NCBI-ProteinID:
XP_037352726
LinkDB
All DBs
Position
Unknown
AA seq
1873 aa
AA seq
DB search
MEPSSPQDEGQRKKQPKKPVPEILPRPPRALFCLTLQNPLRKACISIVEWKPFETIILLT
IFANCVALAVYLPMPEDDNNTLNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFHQDAYLRS
GWNVLDFIIVFLGVFTVILEQVNVIQSHTAPLSNKGAGLDVKALRAFRVLRPLRLVSGVP
SLQVVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYFIGTDIVATVENE
KPSPCARTGSGRPCTINGSECRGGWPGPNHGITHFDNFGFSMLTVYQCITMEGWTDVLYW
VNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLE
EDLRGYMNWITQGEVMDVEDLREGKLSLEEGGSDTESLYEIEGLDKIIKFIRHWRHWNRI
FRWKCHDAVKSRVFYWLVILIVTLNTLSIASEHHHQPIWLTHLQDVANRVLLSLFTVEML
MKMYGLGLRQYFLSVFNRFDCFVVCSGILEILLVESGAMNPLGISVLRCIRLLRLFKITK
YWTSLSNLVASLLNSIRSIASLLLLLFLFIVIFALLGMQLFGGRYDFEDTEERRSNFDTF
PQALISVFQVLTGEDWTSVMYNGIMAYGGPSYPGVLVCIYFIILFICGNYILLNVFLAIA
VDNLAEAESLTSAQKAKAEERKRKKLSKGLPDKSEEEKSVMARKLEQKPKGEGIPTTAKL
KVDEFESNVNEVKDPYPSADFPGDDEEDEPEIPLSPRPRPLAELQLKEKAVPIPEASSFF
IFSPTNKFRVLCHRIVNATWFTNFILLFILLSSAALAAEDPIRAESMRNKILGYFDIAFT
SVFTVEIVLKMTTFGAFLHKGSFCRNYFNILDLLVVAVSLISMGLESSAISVVKILRVLR
VLRPLRAINRAKGLKHVVQCMFVAISTIGNIVLVTTFLQFMFACIGVQLFKGKFFSCNDL
SKMTEEECRGYYYVYKDGDPTQIELRRREWIHNDFHFDNVLSAMMSLFTVSTFEGWPQLL
YKAIDSHTEDVGPIYNKRVEMAIFFIVYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCE
LDKNQRQCVQYALKARPLRCYIPKNPYQYQVWYIVTSSYFEYLMFALIMLNTICLGMQHY
NQSEQMNHISDILNVAFTIIFTLEMVLKLMAFKAKGYFGDPWNVFDFLIVIGSIIDVILS
EIDTFLASSGGLYCLGGGCGNVDPDESARISSAFFRLFRVMRLIKLLSRAEGVRTLLWTF
IKSFQALPYVALLIVMLFFIYAVIGMQMFGKIAMVDGTQINRNNNFQTFPQAVLLLFRCA
TGEAWQEILLACSYGKLCDPESDYAPGEEYTCGTGFAYYYFISFYMLCAFLIINLFVAVI
MDNFDYLTRDWSILGPHHLDEFKAIWAEYDPEATGRIKHLDVVTLLRRIQPPLGFGKFCP
HRVACKRLVGMNMPLNSDGTVTFNATLFALVRTALKIKTEGNFEQANEELRAIIKKIWKR
TSMKLLDQVIPPIGDDEVTVGKFYATFLIQEHFRKFMKRQEEYYGYRPKKDTVQIQAGLR
TIEEEAAPEIRRTISGDLTAEEELERAMEEAAMEEGIFRRTGGLFGQVDNFLERTNSLAP
MVASQRPLQFTEIEMEELESPVFLEDFPQEPSTHPLARANTNNANANIACGNSNHSNNQA
FSSIHYERGFPGEAEPPAAQGGAHSRPQRALGPHSKAHVEKLRGQLTQRAMPSAQATPAL
HQWASGEPPLTEERENPTPGCQPEETPHSHRTEGSPSRCLAPATALLIQEALVRGGLDTL
ASDTGFILVTGHALAEACQMDPEAVEVAAKELLKGRESPEGMDRGLGHLSLRSSLDSLDQ
RQGSQETLIPRRL
NT seq
5622 nt
NT seq
+upstream
nt +downstream
nt
atggagccatcctcaccccaggatgagggtcagaggaagaaacagcccaagaagcccgtt
cctgagatcctgccccggccgccccgggccctgttctgcctcaccctgcagaaccccctg
aggaaggcctgcatcagcatcgtggaatggaagcccttcgagaccatcatcttgctcacc
atctttgccaactgtgtggccctggcggtgtacctgcctatgccagaagatgacaacaac
accctgaacctcggcctggagaaactggagtatttcttcctcatcgtcttctccattgag
gctgcaatgaagatcattgcctatggcttcctgttccaccaagatgcctacctgcgcagt
ggctggaacgtgctggacttcatcattgtcttcctgggggtcttcaccgtgattctggaa
caggttaacgtcatccaaagccacacagccccactgagcaacaaaggagctggtctggat
gtcaaggccctgagagccttccgtgtgctcagacccctccggctggtgtcgggggtgccc
agcctgcaggtggtcctcaactccatcttcaaggccatgctccccttgttccacatcgct
ctgcttgtcctcttcatggttatcatttatgccatcatcgggctggagctcttcaagggc
aaaatgcacaagacctgctacttcattggcacagacatcgtggccacagtggaaaacgag
aagccctcgccctgcgcccggacaggctcagggcgcccatgcaccatcaacggcagcgag
tgccggggtggctggccggggcccaaccacggcatcacccacttcgacaacttcggcttc
tctatgctcaccgtgtaccagtgcatcaccatggagggctggaccgacgtgctgtactgg
gtgaatgatgccatcgggaacgagtggccctggatctattttgtcaccttgattctgctg
ggatccttcttcatcctcaacctggtcctgggtgtcctgagtggggaattcaccaaggag
cgggagaaggccaagtccaggggcactttccaaaagctccgggagaagcagcagctggag
gaagacctgcggggctacatgaactggatcacgcagggcgaggtcatggacgttgaggac
ttgagagaagggaagttgtctttggaagaaggaggctccgacacagagagcctgtatgaa
atcgagggtttggacaaaatcatcaagttcatccgacactggaggcactggaaccgcatc
tttcgctggaaatgccatgacgcggtgaagtccagagtcttctactggctggtcatcctg
atcgtcaccctcaacaccctgtccatcgcctccgagcaccaccaccagccgatctggctg
actcacctgcaagatgttgccaaccgggtgctgctatcgctcttcactgtggagatgctg
atgaagatgtatgggctgggcctgcgccagtacttcctgtccgtcttcaaccgctttgac
tgcttcgtggtgtgcagcggcatcctggagatcctgctggtggagtcgggcgccatgaac
ccgctgggcatctccgtgctgcgctgcatccgcctcctcaggctcttcaagatcaccaag
tactggacatcgctaagcaacctggtggcatccctgctcaactccatccgatccatcgcc
tccctcctgctgctgctgttcctcttcatcgtcatctttgccctgctgggcatgcagctc
ttcgggggcaggtatgactttgaggacacagaggagcggcgcagcaactttgacaccttc
ccgcaggccctcatcagtgtcttccaggtcctgacaggggaggactggacctcggtgatg
tacaacgggatcatggcctacggcggcccatcctaccccggcgtgcttgtgtgcatctat
ttcatcatcctcttcatctgtggcaactatatcctgctcaacgtcttcctggccatcgct
gtggacaatctggctgaggccgagagcctgacttctgcccagaaggccaaggccgaggaa
aggaagcgcaagaagctgtctaagggcctcccagacaaatcagaggaggagaagtctgtg
atggccaggaagctggagcagaaacccaagggcgagggcatccccaccaccgccaagctg
aaagttgatgagtttgaatcaaatgtcaacgaggtgaaggatccctacccctcagctgac
ttcccaggggatgatgaggaagacgagcctgagattccgctgagccccaggccacgacca
ctggctgagctgcagctgaaagaaaaggccgtgcccattccagaagccagctccttcttc
atcttcagtcccaccaataagttccgtgtcctgtgtcaccgcatcgtcaatgccacctgg
ttcaccaactttatcctgctcttcatcctgctcagcagtgctgccctggccgccgaggac
cccatccgggcggagtccatgaggaataagatccttgggtactttgacattgccttcacc
tcagtcttcactgtggagattgtcctcaagatgacaaccttcggcgccttcctgcacaag
ggctccttctgtcgcaactacttcaacatcctggacctgctggttgtggctgtgtccctc
atctccatgggactcgagtccagcgccatctcagtggtgaagatcctgagggtactgcgg
gtgctccggcccctccgggccatcaacagagccaaagggctgaagcatgtggtgcagtgc
atgttcgtggccatcagcaccatcgggaacatcgtcctggtcaccaccttcctgcagttc
atgttcgcctgcatcggggtccagctcttcaaggggaagttcttcagctgcaatgactta
tccaagatgacagaagaggagtgcaggggctactactacgtgtacaaggacggggacccc
acgcagatagagctgcgtcggcgtgagtggatccacaacgacttccacttcgacaacgtg
ctgtcggccatgatgtcactcttcacagtctccaccttcgaggggtggcctcagcttctg
tacaaggccatagactcgcacacagaggacgtgggccccatctacaacaaacgcgtggag
atggccatcttcttcatcgtctacatcatcctcatcgccttcttcatgatgaacatcttc
gtgggcttcgtcatcgtcaccttccaggagcagggggagacagagtacaagaactgtgag
ctggacaagaaccagcgccagtgtgtgcagtatgccctgaaggcccgtccactgaggtgc
tacatccccaaaaacccctaccagtaccaggtgtggtacatcgtcacctcctcctacttt
gaatacctgatgttcgccctcatcatgctcaacaccatctgcctaggcatgcagcactac
aaccagtcagagcagatgaaccacatctcagacatcctcaatgtggccttcaccatcatc
ttcaccttggagatggtcctcaagctcatggcattcaaagccaagggctattttggagac
ccctggaatgtgtttgacttcttgattgtcatcggcagcatcatcgacgtcatcctcagt
gagattgacactttcctggcctccagcgggggactgtattgcctgggtggaggctgcggg
aacgttgacccagacgagagtgcccgcatctccagcgccttcttccgcctgttccgggtc
atgaggctgatcaagctgctgagccgggccgagggggtgcgcacgctgctgtggacattc
atcaagtccttccaggccctgccctatgtggctctgctcatcgtgatgctcttcttcatc
tatgctgtcatcggcatgcagatgttcggaaagatcgccatggtggatgggacccagata
aaccggaacaacaacttccagaccttcccacaggctgtgctgctgctcttcaggtgcgca
acaggtgaggcgtggcaggaaatcctgctggcctgcagctacggcaagctgtgcgacccc
gagtcggattacgccccaggcgaggagtacacgtgtggcaccggcttcgcctactactac
ttcatcagcttctacatgctctgtgccttcctgatcatcaacctctttgtggctgtcatc
atggataacttcgactacctcacgcgggactggtccatcctgggcccgcatcacctggat
gagttcaaggccatctgggcagagtatgatccggaggccacgggcagaatcaaacacctg
gatgtggtgaccctgctgaggaggatccagccccctctgggctttgggaaattctgccca
caccgggtagcatgtaagcgcctggtgggtatgaacatgccgctgaacagcgacggcacc
gtcaccttcaacgccactctctttgccctggtccgcacagcactcaagattaagacagaa
ggtaactttgagcaggccaacgaggagctgagggccatcatcaagaagatctggaagaga
accagcatgaagctcctggaccaggtcattccgccaatcggagatgatgaggtgaccgtg
gggaagttctacgccacattcctgatccaggagcacttccggaagttcatgaagcgccag
gaggaatattatgggtatcggcccaagaaggacaccgtacagatccaggctggactgcgg
accattgaagaggaggcagcccctgagatccgccgcaccatctctggggacctgacagcc
gaagaggagctggagagagccatggaggaggccgcaatggaggaggggatattccggagg
actggaggcctgtttggccaagtggacaacttcctggaaaggaccaactccctcgccccc
atggtggccagccagagacccctccagttcactgagatagagatggaagagctggaatca
cctgttttcttggaggacttccctcaagagccaagcacccatcctcttgctcgggccaat
accaacaacgccaatgccaatattgcctgtggcaacagcaaccatagcaacaaccaggcg
ttttccagcatccactatgaaagggggttccctggagaggcagagccacctgctgcacaa
ggaggagcccacagccgacctcaaagggccctaggaccccacagcaaagcccatgtggaa
aagctgagaggacagctgacccaaagagcgatgcccagtgcccaggccactcctgccctc
caccagtgggccagtggggagcctcccctgactgaggagagggagaatcccaccccaggg
tgtcagcctgaggagacaccccacagccataggaccgaggggagtccttcccggtgcctg
gccccagctacggccctgctaatacaagaggctctggttcgagggggcctggacaccttg
gcatctgacactggcttcatcctagtaactggccacgccctggcagaggcctgccagatg
gacccagaggcagtggaggtggcggccaaggagctgctgaaaggacgagagtccccggag
ggcatggaccgtggcctgggacacctgagcctcaggtcttccctggacagcctggaccag
cgtcagggctcccaggagaccctgattccccgcaggctgtga
DBGET
integrated database retrieval system
