Talpa occidentalis (Iberian mole): 119234334
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Entry
119234334 CDS
T07495
Symbol
PLCE1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X4
KO
K05860
phosphatidylinositol phospholipase C, epsilon [EC:
3.1.4.11
]
Organism
tod
Talpa occidentalis (Iberian mole)
Pathway
tod00562
Inositol phosphate metabolism
tod01100
Metabolic pathways
tod04014
Ras signaling pathway
tod04015
Rap1 signaling pathway
tod04020
Calcium signaling pathway
tod04024
cAMP signaling pathway
tod04070
Phosphatidylinositol signaling system
tod04919
Thyroid hormone signaling pathway
tod04933
AGE-RAGE signaling pathway in diabetic complications
tod05205
Proteoglycans in cancer
Module
tod_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
tod00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
119234334 (PLCE1)
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
119234334 (PLCE1)
04015 Rap1 signaling pathway
119234334 (PLCE1)
04020 Calcium signaling pathway
119234334 (PLCE1)
04070 Phosphatidylinositol signaling system
119234334 (PLCE1)
04024 cAMP signaling pathway
119234334 (PLCE1)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
119234334 (PLCE1)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
119234334 (PLCE1)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
119234334 (PLCE1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
tod04131
]
119234334 (PLCE1)
Enzymes [BR:
tod01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
119234334 (PLCE1)
Membrane trafficking [BR:
tod04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
119234334 (PLCE1)
Endocytosis
Macropinocytosis
Phospholipase C
119234334 (PLCE1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI-PLC-X
PI-PLC-Y
RasGEF
RA
C2
EF-hand_like
GDPD
Motif
Other DBs
NCBI-GeneID:
119234334
NCBI-ProteinID:
XP_037353098
LinkDB
All DBs
Position
Unknown
AA seq
1936 aa
AA seq
DB search
MLSACLRGWFALPSLCGTQFTLLKDGCGCWRLKEDQIYNAVRRGKETEDTIGSLLHFFVK
LPTSEAAHERISIGPCLKPCVRDTVCEYRATLQRTSISQYITGSLLEATTSLGARSGLLS
TFGGSTGRMMLKERQPGTSMANSSALPSSSAGISKELVDLQPLIQFPEEVASILMEQEQN
IYRKVLPVDYLCFLTRDLGTPECQRSLPSLKASISAAILTSQNGEHNALEDLVMRFNEVS
SWVTWLILTAGSMEEKREVFSYLVHVAKCCWNMGNYNAVMEFLAGLRSRKVLKMWQFMDQ
SDLETMRSLKDAMAQHESSCEYKKVVTRALHIPGCKVVPFCGVFLKELCEVLDGASGLMK
LCPRYNSQEETLEFVADYSGQDNFLQRVGQNGLKNSEKESTVNSIFQIIRSCSRSLEAEE
EDCPGEGSSSRKNSLKDKARWQFIIGDLLDSENDIFEQSKEWDLYGSEEPQKAFDHGTEL
IPWYVLSIQADVHQFLLQGATVIHYDQDTHLSARCFLQLQPDNSTLTWTKPTTASSASTK
AKLGVLSNTSEPGKFPLLGSAGLSGLAEGVLDLFSVKAVYMGHPSIDIHTVCVQNKLGSM
LLAETGVTLLYGLQTTDNRLLHFVAPKHTAKMLFSGLLELTRAVRKMRKFPDQRQQWLRK
QYVSLYQDDGRYEGPTLAHAVELFGGRRWSTRNPSPGTSAKSAEKPNMQRNNTLGISTTK
KKKKILMRGESGEATDDEMATRKAKMHKECRSRSGSDPQDVNEQEESEANVIASPPNPLP
SRRAHSLTTANSPNLAAGTSSPIRPVSSPVLSANKIPSSAWSSSSWHGRITGGMKGFQNL
MVSDSNMSFVEFVELFKSFSVRSRKDLKDLFDIYAVPCNRAGPEPAPLYTNLTIDENTSD
LQPDLDLLTRNVSDLGLFIKSKQQLSDNQRQISDAIAAASIVTNGTGVESTSLGIFGVGI
LQLNDFLVNCQGEHWTYDEILSIIQKFEPSVSMCHQGLMSFEGFARFLMDKDNFASKNDE
SQESTKELQLPLSYYYIASSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDCWDGDDG
MPIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENHCSLPQQRKMAEIFKTVFG
EKLVAKFLFESDFSDDPMLPSPDQLRRKVLLKNKKLKAHQTPVDILKQKAHQLASMQAQA
YYGGNATSAPANNEEEEDEEDEYDYDYESLSDDNILEDRPENKSCNDKLQFEYNEEIPKR
IKKADTSVYNKGKVYDMELGEEFYLPQNKKESRQIAPELSDLVIYCQAVKFPGLSTLNAS
GSNRGKERKSRKSIFGNNPGRMSPGETAPFNKTSGKSSCEGMRQAWEESSSPLNPTTSLS
AIIRTPKCYHISSLNENAAKRLCRRYSQKLIQHTACQLLRAYPAATRIDSSNPNPLMFWL
HGIQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLERDLDNM
EPAVYSLTIVSGQNVCPSNSTGSPCIEVDVLGAPLDSCHFRTKPIHRNTLNPMWNEQFLF
RVHFEDLLFLRFAVVENNSSAITAQRIIPLKALRRGYRHLQLRNLHNEVLEISSLFINSR
RMEENPSGSTMPASLMFNTEERKYLQTHRVTVHGVPGPEPFTVFCINGGTKAKQLLQQIL
TIEQDISPSATDYFLMEEKYFISKEKNECRKQPFQRVIGLEEEISQILSSWFPEEGYVGR
IVLKTQQENFEEKCIVQDDKEVILSSEMESFFVQVHDVSPEQPRTVIKAPRVSTAQDVIQ
QTLCKAKYSYSILSNPNPSDYVLLEEVVKDTTNKKTSAPKSSQRVLLDQECVFQVQSKWK
GAGKFILKLKEQVQASREDKRKGISFASEFKKLTKSTKQPRGLTSPSLVLASESVQNKEE
KPVGSLSSTDVIDYRQ
NT seq
5811 nt
NT seq
+upstream
nt +downstream
nt
atgctctcagcctgccttagggggtggttcgctcttccttctctctgcggtacccaattt
accttattaaaggatggatgcggatgctggaggcttaaagaagaccagatctacaatgca
gtgagaaggggaaaagaaacagaagatacaattggatctcttctccatttcttcgtaaag
ctcccaacctcagaggcagcccatgaaaggattagcattggcccgtgcttaaagccgtgt
gtccgggacactgtatgtgagtatcgtgctaccctccaaaggacttccatatctcagtac
atcaccggctctctcctagaagccaccacatctttaggagcaagaagtggcctactcagt
acattcggaggatccactggacgcatgatgctgaaagaacgccaaccaggtacctctatg
gctaattccagtgccctcccttcaagttcagctgggatcagcaaagaactggttgatcta
cagcccctcatccagttcccagaggaagttgccagcatcctaatggagcaggaacagaat
atttaccggaaggtcttgccagttgattacctttgcttcttaactcgggacttgggcact
ccagaatgtcagagatccctgccctcccttaaagcatccatctcagcagcaattcttacc
tcccagaatggagaacacaatgcccttgaagatcttgtgatgagattcaatgaggtgagc
tcctgggtgacgtggctgatcctcactgcaggctccatggaggagaagcgggaagtcttc
tcatacttggtgcatgtggccaaatgctgctggaacatgggcaactacaacgctgtcatg
gagttcttggctggcctcaggtcacgaaaagttttaaaaatgtggcagttcatggaccag
tctgatctggagaccatgaggagcctgaaggacgcaatggctcagcacgaatcttcttgc
gagtacaagaaggtggtgacccgggcactgcacatccccggctgtaaagtggttccattt
tgtggggtgtttctgaaggagctctgtgaagtgctcgatggagcctctggcctcatgaag
ctttgcccgaggtacaattcccaagaagaaactttagagtttgtagccgattacagtgga
caagataatttcttacaaagagtggggcaaaatggcttaaagaattcggagaaggagtcc
acagtcaacagcatctttcagatcatcaggagctgcagcaggagcctggaggcggaggaa
gaggactgcccgggggaagggagcagctccaggaagaattccttgaaggataaagcccga
tggcagtttataatcggagatttgctggattctgaaaatgacatctttgaacagtctaaa
gaatgggacctttatgggtcagaggagccacagaaggcctttgaccatgggacagagctc
atcccatggtatgtgctgtccatccaggccgatgtgcatcagttcctgctacagggggcc
acagtcatccactatgaccaggacactcacctctctgcccgctgcttcctccagcttcag
cctgacaatagcaccttgacctggacaaagcccaccacggcctcctcagccagtactaaa
gcaaaactcggtgtgcttagtaacacatctgagcctggtaaatttccgttactgggcagt
gctggattaagtggcctagcagagggggtcttggacctgttttcagtgaaggctgtgtac
atgggacaccctagcattgatatacacactgtgtgtgttcagaacaaactgggtagcatg
cttctcgcagagactggtgtgacactgctctatggacttcaaaccacagacaatagatta
ttgcattttgtggccccaaagcacacagctaaaatgctcttcagtggattgttggaactc
actagagctgtaagaaagatgaggaagtttcccgaccaaagacagcagtggctgcggaaa
cagtatgtcagcctctatcaggatgatgggcgatatgaaggcccaactttggctcatgct
gtggagttgtttggtggcagacgatggagtactcgaaaccccagccctgggacatcagca
aagagtgccgagaagcctaacatgcagagaaacaacaccttgggcataagcaccaccaag
aaaaagaagaaaatccttatgagaggtgagagtggagaggcaactgatgacgagatggcc
accagaaaggctaaaatgcacaaagagtgtcggagccggagtgggtctgaccctcaagac
gttaatgaacaagaagaatcagaggcgaatgtcatcgctagccctcctaaccctctccct
tccagaagagcccactctttgaccacggctaactcccctaacttggctgccgggacgtca
tctcccatcaggccagtgtcctcccctgtgctgtctgcaaacaagatcccatccagtgca
tggagcagcagcagctggcatgggcggatcacaggaggaatgaagggctttcaaaacctc
atggtttcagacagtaacatgagttttgttgaattcgttgagctgttcaaatcattcagt
gtcaggagccgcaaggacctgaaggacctctttgacatctacgcggtaccctgcaaccga
gccggccccgagccagccccactctacaccaacctgacaatcgatgagaacaccagcgac
cttcagcctgacctcgatttgttgaccagaaatgtctcagatttgggcttgttcattaag
agtaaacagcagttgtcggacaaccaaaggcagatatctgatgccattgctgctgcaagc
atcgtgacaaatggcactggggtcgagagcacgtctctgggcatcttcggggttggcata
ctccagctcaatgacttcctcgtgaattgccaaggagagcactggacctatgatgagatc
ctcagcatcatccagaagttcgagcctagtgttagtatgtgtcaccagggcctcatgtca
tttgaaggatttgcaaggtttctgatggataaagataattttgcctcgaaaaatgatgag
tcacaggagagcactaaggagttgcagctgcccctctcctactattacatagcatcttca
cacaacacctacctcacaggccatcagctcaaaggagaatcctcagtagaactctacagc
caggtcctgctgcaaggctgtaggagcgtagagttggactgctgggatggtgatgatggg
atgcccatcatttatcatggacacacactgacaactaagatccccttcaaggaggtggta
gaagccatagatcgcagtgccttcatcaactctgacctgccaatcatcatatccattgag
aaccactgttcgctgcctcagcaacgaaaaatggcagaaattttcaagactgtgtttgga
gaaaaactggttgctaaatttttatttgagagtgatttctcagatgacccaatgcttcct
tcacctgaccaactcaggaggaaagtgcttcttaaaaataagaagctaaaagcccatcag
acgccagtagatatcttaaagcagaaggctcatcagttagcatccatgcaagctcaggct
tattatggtggaaatgccacttctgcacctgctaataatgaggaagaggaagatgaagag
gatgaatatgattatgattatgaatccctctctgatgacaacattctagaagacagacct
gaaaataaatcatgtaatgacaagcttcagtttgagtataatgaagaaattcccaagagg
ataaagaaagcagatacttctgtttacaataaaggaaaggtttatgacatggaattggga
gaagaattttatcttccacagaataaaaaggaaagcagacagattgcaccagagctttct
gaccttgtcatttattgccaagcagtgaaatttccaggcctgtcaactctaaatgcatct
ggctctaacagaggaaaagaaaggaaaagcaggaagtccatttttggcaacaatccgggc
agaatgagcccaggggagacagcaccgtttaacaaaacatctggaaaaagttcctgtgaa
ggaatgcgacaggcctgggaggaatcttcttcccccctcaacccaaccacatccctcagc
gctatcattagaactcccaaatgttaccatatctcatcgctgaatgaaaatgccgccaaa
cgtctgtgtcgcaggtattctcagaaactgatccagcacaccgcctgccagctgctgagg
gcctacccggccgccacccggatcgactcctccaaccccaaccccctcatgttctggctc
catgggatacagctcgtggcactcaactaccagacagatgatctccctttacatttaaat
gctgccatgtttgaggccaacggtggctgtggttatgttttgaaacccccggttctgtgg
gacaagaattgtcccatgtatcagaaattttctcctttggaaagagacttagacaacatg
gagcctgctgtctattctttaactattgtctctggtcaaaatgtgtgcccaagcaacagc
acaggaagcccgtgtatcgaagttgacgtcctcggcgcgcctctggacagctgccacttc
cgcacgaagcccatccacagaaacaccctgaaccccatgtggaatgagcagtttctcttc
cgggtgcactttgaagatctcctgttccttcgctttgcagtcgtggaaaacaacagctcg
gcaatcactgctcagagaatcatccccctcaaggcactcagacgaggatatcgacatctt
cagttgcgaaacctccacaatgaagtcttggaaatctctagtttattcattaacagcaga
aggatggaagaaaacccctctggcagtacgatgccagcctctttgatgtttaacacagaa
gaaagaaaatatttgcagactcacagggtcacagtacatggagtcccaggtccagagccc
tttactgttttctgtataaatggaggcaccaaggcaaagcagcttctccaacagattcta
accattgaacaagacatcagccctagtgccacagactattttttgatggaagaaaaatat
tttatatctaaagaaaagaatgaatgtaggaaacaaccgttccagagagtcatcggtctt
gaagaagagatctcccagatcttaagcagctggtttccagaagagggatatgttggcagg
attgtcttaaaaacccagcaggaaaacttcgaagagaaatgcatcgttcaagacgacaag
gaggtgatcttgagctcagagatggagagtttctttgtccaggtccatgacgtttcccca
gagcaacctcgaacggtcatcaaagcgcctcgcgtcagcactgcgcaggacgtcatccag
cagactttatgcaaagccaaatattcctatagcatcctgagcaaccccaacccaagtgac
tacgtgcttttggaagaggtggtgaaggacactaccaacaagaagacgtctgctccaaag
tcctcccagagggtccttttggatcaggagtgtgtgtttcaagtccaaagcaagtggaaa
ggtgcaggaaaattcatccttaagctgaaggagcaggtgcaggcatcccgagaagacaaa
agaaaaggcatttcttttgcaagtgaattcaagaagctcaccaagtcaaccaaacagccc
cgaggacttacatcaccatctctggtcttggcttcggaaagtgtccaaaataaggaggag
aaacctgtgggcagcttgtcctccactgacgtgatagactatcggcagtga
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integrated database retrieval system
