Talpa occidentalis (Iberian mole): 119239071 Help Entry 119239071         CDS       T07495                                  Symbol SOS2 Name (RefSeq) son of sevenless homolog 2   KO K03099   son of sevenless Organism tod  Talpa occidentalis (Iberian mole) Pathway tod01521   EGFR tyrosine kinase inhibitor resistance tod01522   Endocrine resistance tod04010   MAPK signaling pathway tod04012   ErbB signaling pathway tod04014   Ras signaling pathway tod04062   Chemokine signaling pathway tod04068   FoxO signaling pathway tod04072   Phospholipase D signaling pathway tod04150   mTOR signaling pathway tod04151   PI3K-Akt signaling pathway tod04510   Focal adhesion tod04540   Gap junction tod04630   JAK-STAT signaling pathway tod04650   Natural killer cell mediated cytotoxicity tod04660   T cell receptor signaling pathway tod04662   B cell receptor signaling pathway tod04664   Fc epsilon RI signaling pathway tod04714   Thermogenesis tod04722   Neurotrophin signaling pathway tod04810   Regulation of actin cytoskeleton tod04910   Insulin signaling pathway tod04912   GnRH signaling pathway tod04915   Estrogen signaling pathway tod04917   Prolactin signaling pathway tod04926   Relaxin signaling pathway tod04935   Growth hormone synthesis, secretion and action tod05034   Alcoholism tod05160   Hepatitis C tod05161   Hepatitis B tod05163   Human cytomegalovirus infection tod05165   Human papillomavirus infection tod05200   Pathways in cancer tod05205   Proteoglycans in cancer tod05206   MicroRNAs in cancer tod05207   Chemical carcinogenesis - receptor activation tod05208   Chemical carcinogenesis - reactive oxygen species tod05210   Colorectal cancer tod05211   Renal cell carcinoma tod05213   Endometrial cancer tod05214   Glioma tod05215   Prostate cancer tod05220   Chronic myeloid leukemia tod05221   Acute myeloid leukemia tod05223   Non-small cell lung cancer tod05224   Breast cancer tod05225   Hepatocellular carcinoma tod05226   Gastric cancer tod05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:tod00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     119239071 (SOS2)    04012 ErbB signaling pathway     119239071 (SOS2)    04014 Ras signaling pathway     119239071 (SOS2)    04630 JAK-STAT signaling pathway     119239071 (SOS2)    04068 FoxO signaling pathway     119239071 (SOS2)    04072 Phospholipase D signaling pathway     119239071 (SOS2)    04151 PI3K-Akt signaling pathway     119239071 (SOS2)    04150 mTOR signaling pathway     119239071 (SOS2)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     119239071 (SOS2)    04540 Gap junction     119239071 (SOS2)   09142 Cell motility    04810 Regulation of actin cytoskeleton     119239071 (SOS2)  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     119239071 (SOS2)    04660 T cell receptor signaling pathway     119239071 (SOS2)    04662 B cell receptor signaling pathway     119239071 (SOS2)    04664 Fc epsilon RI signaling pathway     119239071 (SOS2)    04062 Chemokine signaling pathway     119239071 (SOS2)   09152 Endocrine system    04910 Insulin signaling pathway     119239071 (SOS2)    04912 GnRH signaling pathway     119239071 (SOS2)    04915 Estrogen signaling pathway     119239071 (SOS2)    04917 Prolactin signaling pathway     119239071 (SOS2)    04926 Relaxin signaling pathway     119239071 (SOS2)    04935 Growth hormone synthesis, secretion and action     119239071 (SOS2)   09156 Nervous system    04722 Neurotrophin signaling pathway     119239071 (SOS2)   09159 Environmental adaptation    04714 Thermogenesis     119239071 (SOS2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     119239071 (SOS2)    05206 MicroRNAs in cancer     119239071 (SOS2)    05205 Proteoglycans in cancer     119239071 (SOS2)    05207 Chemical carcinogenesis - receptor activation     119239071 (SOS2)    05208 Chemical carcinogenesis - reactive oxygen species     119239071 (SOS2)    05231 Choline metabolism in cancer     119239071 (SOS2)   09162 Cancer: specific types    05210 Colorectal cancer     119239071 (SOS2)    05225 Hepatocellular carcinoma     119239071 (SOS2)    05226 Gastric cancer     119239071 (SOS2)    05214 Glioma     119239071 (SOS2)    05221 Acute myeloid leukemia     119239071 (SOS2)    05220 Chronic myeloid leukemia     119239071 (SOS2)    05211 Renal cell carcinoma     119239071 (SOS2)    05215 Prostate cancer     119239071 (SOS2)    05213 Endometrial cancer     119239071 (SOS2)    05224 Breast cancer     119239071 (SOS2)    05223 Non-small cell lung cancer     119239071 (SOS2)   09172 Infectious disease: viral    05161 Hepatitis B     119239071 (SOS2)    05160 Hepatitis C     119239071 (SOS2)    05163 Human cytomegalovirus infection     119239071 (SOS2)    05165 Human papillomavirus infection     119239071 (SOS2)   09165 Substance dependence    05034 Alcoholism     119239071 (SOS2)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     119239071 (SOS2)    01522 Endocrine resistance     119239071 (SOS2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  RasGEF RasGEF_N RhoGEF SOS1_NGEF_PH PH IQ_SEC7_PH PH_19 RHG20_PH PH_10 PH_13 Motif Other DBs NCBI-GeneID:  119239071 NCBI-ProteinID:  XP_037359190 LinkDB All DBs Position Unknown AA seq 1332 aa AA seqDB search MQQAPQPYEFFSEENSPKWRGLLVSALRKVQEQVHPNLSANEESLYYIEELIFQLLNKLC MAQPRSVQDVEERVQKTFPHPIDKWAIADAQSAIEKRKRRNPLLLPVDKIHPSLKEVLGY KVDYHVTLYIVAVLEYISADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQDD IGLVSLCEDEPSSSGELNYYDLVRTEIAEERQYLRELNMIIKVFREAFLSDRNLFKTSDI EKIFSNISDIHELTVKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQDI LSPKFNEHFSKLMTRPAVALHFQSIADGFKEAVRYVLPRLMLVPVYHCWHYFELLKQLKA CSEEQEDRECLNQAITALMNLQGSMDRIYKQYSPRRRPGDPVCPFYNRQLRSKHLAIKKM NEIQKNIDGWEGKDIGQCCNEFIMEGPLTRIGAKHERHIFLFDGLMISCKANHSQSRLPG YSSAEYRLKEKFVMRKIQICDKEDTCEYKHAFELVSKEESSIIFAAKSAEEKNNWMAALI SLHYRSTLDRMLDSVLLKEENEQPLRLPSPEMYRFVVKDSEENIVFEDNLQSRSGIPIIK GGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTEADKLA VEKGEQPISADLKRFRKEYVQPVQLRILNVFRHWVEHHFYDFERDLELLERLESFISSVR GKAMKKWVESIAKIIKRKKQAQANGISHNITFESPPPPIEWHISRPGQFETFDLMTLHPI EIARQLTLLESDLYRKVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVEA ENFEERVAVLSRIIEILQVFQDLNNFNGVLEIVSAVNSVSVYRLDHTFEALQERKRRILD EAVELSQDHFKKYLVKLKSINPPCVPFFGIYLTNILKTEEGNNDFLKKKGKDLINFSKRR KVAEITGEIQQYQNQPYCLRIEPEIRRFFENLNPMGSASEKEFTDYLFNKSLEIEPRNCK QPPRFPRKSTFSLKSPGIRPNTGRHGSTSGTLRGHPTPLEREPCKMSFSRIAETELESTV SAPTSPNTPSTPPVSASSDLSVFLDVDLNSSCGSNSIFAPVLLPHSKSFFSSCGSLHKLS EEPLIPPPLPPRKKFDHDATNSKGNMKSDGDPPAIPPRQPPPPKVKPRVPASIGAFDGSL HSPPPPPPRDPLPDTPPPVPVRPPEHFINYPFNLQPPPLGHPHRDQDWFRDVSTCPNSPN TPPSTPSPRVPRRCYMHNSSHNNLTHPQAPPVPPRQNSSPHLPKLPPKTYKRELSHPPLY RLPLLENAETPQ NT seq 3999 nt NT seq  +upstreamnt  +downstreamnt atgcagcaggcgccgcaaccgtacgagttcttcagcgaggagaacagcccgaaatggcgg ggactgctggtctcggccctgcggaaggttcaggagcaagtacatccaaatctctcagct aatgaagagtcactctattatattgaagagctgattttccagctgctcaataaattatgt atggcccaaccaaggagtgttcaagatgtggaggaacgagttcaaaagacctttcctcat ccaattgataaatgggctattgctgatgcccaatctgccatagagaaacgaaaacgaagg aatcctcttttactgcctgtggacaaaatccatccttcattaaaggaagttttagggtac aaagtggactaccatgtgaccctatatattgtggctgtattagagtatatttcagctgat attttgaaattggctggtaattatgttttcaatatccgacattatgaaatatctcagcag gacattaaagtatccatgtgtgcagataaggttttaatggacatgtttgatcaggatgac ataggtttggtttctctctgtgaagatgaacctagttcttcaggtgaattaaactactat gaccttgtcagaactgaaattgcagaagaaagacagtatctacgggagctaaatatgatc ataaaagtttttcgagaagcctttctttctgacagaaatctgtttaagacttctgatatt gaaaagattttcagtaacatttcagatatacatgaattgactgtgaaacttttaggtttg attgaagacacagttgaaatgactgatgaaagcagtcctcatcctttagcaggcagctgt tttgaagatttggcagaagagcaagcatttgatccttatgaaacactatcacaggatatt ctttctccaaaatttaatgaacatttcagtaagttgatgaccagacctgcagtggctctg catttccagtccatcgctgatggttttaaagaggcagttcgttatgtccttccacgcctt atgctggtgccagtatatcattgttggcactattttgaattattaaagcaattgaaagca tgtagtgaagagcaggaagacagagaatgtttgaaccaagctattactgctctcatgaat ctccaaggtagcatggaccgaatttacaagcagtattcccctagacgccgacctggggat cctgtttgccctttttataatcgtcaattaagaagcaagcacctagctattaaaaaaatg aatgaaattcagaaaaacatagatggatgggaaggcaaagatattggacagtgttgtaat gaattcattatggaaggtccattgacaagaattggtgctaaacatgaacggcatattttt ctctttgatggtttaatgattagctgtaaagccaatcatagccagtctcgacttccaggt tatagtagtgcagaatacaggttaaaagagaaatttgtcatgaggaaaatacaaatatgt gataaagaagatacttgtgagtacaaacatgcttttgaattagtatccaaagaagaaagt agcataatatttgctgctaagtctgctgaagagaaaaataattggatggcagcgcttatt tctcttcattatcggagtactcttgatcgaatgctagattcagtattattgaaagaggaa aatgagcaaccactcagattaccaagtcctgaaatgtatcgttttgtggtaaaagactct gaggaaaacattgtttttgaagacaacttgcaaagtagaagtggaatccccattattaaa ggaggaactgtggtgaaattaattgaaaggttaacatatcatatgtatgcagatcccaat tttgttcgtacttttcttactacatatcgatcattttgtaaaccacaggaattgctaagc ctactgattgaacgatttgaaattccagagccagaacctacggaagcagataaactagct gtagagaaaggtgaacagcctatcagtgcagaccttaaaagatttcgcaaggaatacgtc caaccagtacaacttaggatcttaaatgtttttcggcactgggttgaacatcatttttat gactttgaaagagatttggagttgcttgaaagactagaatccttcatttcaagtgtaaga ggaaaagctatgaagaaatgggtagagtcaattgctaagatcatcaaaaggaagaaacaa gcccaggcaaatggaataagccataatattacctttgaaagcccacctccaccaattgag tggcatatcagcagaccaggacaatttgaaacatttgatctcatgacacttcatccaata gaaattgcacgtcagctaacacttttagaatctgatctctacaggaaagtccaaccatct gaacttgtagggagtgtatggaccaaagaagataaagaaataaattctccaaatttatta aaaatgattcgccataccacaaatcttactctctggtttgaaaagtgcattgtggaagca gaaaattttgaggaacgagtggcagtgctaagtagaattatagaaattctgcaagttttt caagatttgaataatttcaatggtgtattggagatagtcagtgcagtaaattcagtgtca gtgtatagattagaccatacctttgaggcattgcaggaaagaaaaaggagaattttggat gaagctgtggaactaagtcaagatcactttaaaaaatacctagtaaaacttaagtcaatc aatccaccttgtgtgcctttttttggaatatatttaacaaatattctgaagactgaagaa ggaaataacgattttttgaaaaagaaagggaaagatctaatcaatttcagtaagaggaga aaagtagctgaaattactggagaaattcaacagtatcagaatcaaccttactgtttacga atagaaccagaaataaggagattctttgaaaatcttaaccccatgggaagtgcttctgaa aaagagtttacagattatttgttcaacaagtcactagaaattgaaccccgaaactgcaaa cagccacctcgatttcctaggaaatcaaccttctctttaaaatctcctggaataaggcct aatacaggccggcatggctctacctcaggcactttacgaggtcatccaacaccattggaa agagaaccatgtaaaatgagctttagtcgaattgctgaaactgagcttgaatcaacagtg tcagcaccaacctctccaaatacaccatctactccaccagtatctgcttcttcagacctt agtgtgtttttagatgtggatctcaacagctcatgtggcagcaatagcatatttgctcca gtccttttgcctcattcaaagtctttcttcagttcgtgtggtagtttacataaactaagt gaagagccgctgattcctccacctcttcctcctcgaaaaaagtttgatcatgatgctaca aattccaagggaaatatgaaatctgatggtgatccccctgctattccaccaagacaacct cctcctccaaaagtaaaacccagagttcctgcttctattggtgcatttgatggatctctg catagtccacctccaccgcctccaagagatcctcttcctgacacccctccaccagttccc gttcgacctccagaacactttataaactatccatttaaccttcagccacctccactagga catcctcatagagatcaagactggttcagagacgttagtacatgtccaaattcaccaaac actcctcctagcacaccctctccaagggtaccacgtcgatgttatatgcacaattctagt cacaataatcttactcatcctcaagctccccctgttccaccacggcagaattcaagccct cacctaccaaaactgccaccaaagacttacaaacgggagctttcgcatcccccattgtac agactgcctttgctagaaaatgcagaaactcctcaatga

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