Talpa occidentalis (Iberian mole): 119240713
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Entry
119240713 CDS
T07495
Symbol
BACE1
Name
(RefSeq) beta-secretase 1 isoform X1
KO
K04521
beta-site APP-cleaving enzyme 1 (memapsin 2) [EC:
3.4.23.46
]
Organism
tod
Talpa occidentalis (Iberian mole)
Pathway
tod05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
tod00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
119240713 (BACE1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
tod01002
]
119240713 (BACE1)
Enzymes [BR:
tod01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.23 Aspartic endopeptidases
3.4.23.46 memapsin 2
119240713 (BACE1)
Peptidases and inhibitors [BR:
tod01002
]
Aspartic peptidases
Family A1: pepsin family
119240713 (BACE1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Asp
TAXi_C
TAXi_N
PE-PGRS_C
Motif
Other DBs
NCBI-GeneID:
119240713
NCBI-ProteinID:
XP_037361239
LinkDB
All DBs
Position
Unknown
AA seq
501 aa
AA seq
DB search
MAQALPWLLLWMGSGMLPAHCTQPGIRLPLRSGLGGALLGLRLPRETDEEQEEPSRRGSF
VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSST
YRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGIL
GLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPFNQSEALASVGGSMIIGGI
DHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKK
VFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRIT
ILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSAC
HVHDEFRTAAVEGPFVTPDMEDCGYNIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQW
RCLRCLRHQHDDFADDISLLK
NT seq
1506 nt
NT seq
+upstream
nt +downstream
nt
atggcccaagcactgccctggctcctgctgtggatgggctccggcatgctgcctgcccac
tgcacccagcctggcatccgactgcccctgcgaagcgggcttgggggggccctcctgggg
ctgcgactaccccgggagaccgacgaggagcaggaggagcccagccggagaggcagcttt
gtggagatggtggacaacctgaggggcaagtctggccagggctactatgtggagatgacc
gtgggcagccccccacagacgcttaacatcctggtggatacaggcagcagtaattttgca
gtgggggctgcgccccaccctttcctgcatcgctactaccagcggcagctgtccagcacc
taccgggacctgcgaaagggcgtgtatgtgccctacacccagggcaagtgggagggggag
ctgggcaccgacctggtgagcatcccccatggtcccaatgtcaccgtgcgtgccaacatc
gctgccatcactgaatcagacaagttcttcatcaatggctccaactgggagggcatcctg
gggttggcctatgctgagatcgccaggcctgatgactccttggagcctttctttgactcc
ttggtaaagcagacccacgttcccaacctcttctccctgcagctctgtggtgctggcttt
cccttcaaccagtcagaagcactggcctcagttggagggagcatgatcattgggggcatc
gaccactcgctgtacacaggcagtctctggtacacacccatccggcgggagtggtattat
gaggtgatcattgtgcgggtggagatcaacggacaggatctgaaaatggactgcaaggag
tacaactatgacaagagcattgtggacagtggtaccaccaacctgcgtctgcccaagaaa
gtgtttgaagctgctgtcaaatccatcaaggcagcctcctcgacggagaagtttccagac
ggtttctggctcggggagcagctggtatgctggcaagcaggcaccaccccttggaacatt
ttcccagtcatctccctctacctaatgggtgaagtcaccaatcagtccttccgcatcacc
atccttccacagcaataccttcggccagtggaagatgtggccacatcccaagatgactgt
tacaaattcgccatctcacagtcctccacgggcactgttatgggagctgttatcatggag
ggcttctacgtggtctttgatcgggcccgaaaacgaattggctttgccgtcagcgcttgc
catgtacacgatgaattcaggacggcagcagtggaaggtccttttgtcactccggacatg
gaagactgtggctacaacattccccagacagatgaatccaccctcatgaccattgcctat
gtcatggctgccatctgcgctctcttcatgctgccactctgcctcatggtgtgtcagtgg
cgctgcctccgctgcctccgccatcaacacgatgactttgctgatgacatctccctgctg
aagtga
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