Heme biosynthesis, animals and fungi, glycine => heme
Brite
KEGG Orthology (KO) [BR:tod00001]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
119240747 (HMBS)
Enzymes [BR:tod01000]
2. Transferases
2.5 Transferring alkyl or aryl groups, other than methyl groups
2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
2.5.1.61 hydroxymethylbilane synthase
119240747 (HMBS)
361 aa
MSGNGSAAATAEENNPKMRVIRVGTRKSQLARIQTDSVVATLKALYPSLQFEIIAMSTTG
DKILDTALSKIGEKSLFTKELEHALERNEVDLVVHSLKDLPTVLPPGFTIGAICKRENPY
DAVVFHPKFVGKTLETLSEKSVVGTSSLRRAAQLQRKFPHLQFKSIRGNLNTRLRKLDEQ
QEFSAIVLAVAGLQRMGWQNRVGQILHPEECMYAVGQGALGVEVRANDQDILDLVGVLHD
PETLLRCIAERAFLRQLEGGCSVPVAVHTVMKDGQLYLTGGVWSLDGSDSMQETMQATIH
VPAQHEDGPEDDPQLVGITARNIPRGAQLAAENLGISLANLLLNKGAKNILDVARQLNDA
H
