Talpa occidentalis (Iberian mole): 119240943
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Entry
119240943 CDS
T07495
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
tod
Talpa occidentalis (Iberian mole)
Pathway
tod04217
Necroptosis
tod04380
Osteoclast differentiation
tod04620
Toll-like receptor signaling pathway
tod04621
NOD-like receptor signaling pathway
tod04630
JAK-STAT signaling pathway
tod04658
Th1 and Th2 cell differentiation
tod04659
Th17 cell differentiation
tod05145
Toxoplasmosis
tod05160
Hepatitis C
tod05161
Hepatitis B
tod05162
Measles
tod05164
Influenza A
tod05165
Human papillomavirus infection
tod05167
Kaposi sarcoma-associated herpesvirus infection
tod05168
Herpes simplex virus 1 infection
tod05169
Epstein-Barr virus infection
tod05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
tod00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
119240943 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
119240943 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
119240943 (TYK2)
04621 NOD-like receptor signaling pathway
119240943 (TYK2)
04658 Th1 and Th2 cell differentiation
119240943 (TYK2)
04659 Th17 cell differentiation
119240943 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
119240943 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
119240943 (TYK2)
05160 Hepatitis C
119240943 (TYK2)
05171 Coronavirus disease - COVID-19
119240943 (TYK2)
05164 Influenza A
119240943 (TYK2)
05162 Measles
119240943 (TYK2)
05168 Herpes simplex virus 1 infection
119240943 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
119240943 (TYK2)
05169 Epstein-Barr virus infection
119240943 (TYK2)
05165 Human papillomavirus infection
119240943 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
119240943 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
tod01001
]
119240943 (TYK2)
Enzymes [BR:
tod01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
119240943 (TYK2)
Protein kinases [BR:
tod01001
]
Non-receptor tyrosine kinases
JAK family [OT]
119240943 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
SH2_1
FERM_F1
Kinase-like
Kdo
ABC1
FERM_C_FAK1
Motif
Other DBs
NCBI-GeneID:
119240943
NCBI-ProteinID:
XP_037361657
LinkDB
All DBs
Position
Unknown
AA seq
1172 aa
AA seq
DB search
MPLCQWGAISKASKLDRDGAQPLATTRGGLKVLLHWAGPGGGDPWVIFTEDTLTAEEICI
HIAHKVGITPPCFNLFALFDAQAQVWLPPNHILQACRDRSLMLYFRMRFYFRNWHGMNPQ
EPTVYRCGPPGTEVSSGRAEQGVQLLDPASFEYLFEQGKYEFVNDVASLEELWNEEEIHH
FKNESLGMAFLHLCHLALCRGVPLEEVAKKISFKDCIPRSFRRQIRQHDVLTRLRLRTIF
HRFLRDFQPGRLSQQVVMVKYLATLECLAPRFGTERMPVYQLELLTQTAGAPCYIRDSGQ
ALLEPTPASAARPPTHEVLVTGTGGIQWRPLLAVGPSSSVRNRPAGPAGKKAKAHEGSNQ
PADKPREAQWTYFCDFRDITHMVLKECHVSIRCQDKFLELALPSRAAALSLVSLLDGYFR
LTSDSSHYLCHEVAPPRLVMSIQEGIHGPLLEPFVLAKLRPEDGLYLIHWSTTHFNRLIL
TVAQHDQASSAKSWRLRKFPIELQAGAFTLEGWDRSFPSVRDLRAALQGCSLRSGQDCFS
LHRCCLPQPGEFSNLVILRGSCASTRPPNLSHLSFHRVSWDKITRLSHLGQGTRTNVYEG
LLLVTDRGPEEDKADDGGPGQDLRVVLKVLDPSHHNIALAFYETASLMSQVSHVHLAFVH
GVCVHGSENIMVTEYVEHGPLDVCLRRERGHVPVAWKVVVAQQLASALSYLEDKSLVHGN
VCGRNILLARLGLVEGTSPFIKLSDPGVGLGALSREERVERIPWIAPECLSGVDSSLSTA
ADKWGFGATLLEICFDGEILLQGRGPSEKEHFYQKQHQLPQPSSPELAVLTSQCLNYEPG
QRPSFRTILRDLTRLQPQNLDVSAVNPDSPTSDSTVFHKRYLKKIRDLGEGHFGKVSLYC
YDPNNDGTGEMVAVKALKAGCSPQLLPGWTREIDILRTLYHKHIVKYKGCCGDQGEKSVQ
LVMEYVPLGSLRDYLPRHSVGLAQLLLFALQICEGMAYLHSQHYIHRDLAARNVLLDNDK
LVKIGDFGLAKAVPEGHEYYRVHEDGDSPVFWYAPECLKECKFYYASDVWSFGVTMYELL
THCDSSQSPPSKFIELIGLNQGQRTVLRLTELLEQGERLPQPDKCPCEIYLLMKNCWEAE
ASFRPTFQNLIPILKTVHEKYQGQAPSVFSVC
NT seq
3519 nt
NT seq
+upstream
nt +downstream
nt
atgcctctgtgccagtggggtgccatcagcaaggccagcaaactggacagggatggagct
cagcccctggccaccaccagaggaggcctgaaagtgcttctgcactgggccggccctgga
ggtggtgacccctgggtcatcttcaccgaggacaccctgacagcagaggagatttgcatc
cacatcgcacacaaagttggcatcactccaccctgctttaatctcttcgccctctttgat
gcccaggcccaagtctggttacccccaaaccacatactgcaggcctgtagagacaggagc
ctaatgttgtacttccgtatgaggttttatttccggaactggcatggcatgaatcctcag
gagccgactgtataccgttgtgggcccccagggactgaggtttcctcaggacgggcagag
cagggggtgcagctcctggacccagcctcctttgagtatctctttgagcagggcaagtat
gagtttgtgaatgacgtggcatcgttggaggagctgtggaatgaggaggagatccaccac
tttaagaatgagagtttgggcatggcttttctgcatctctgccaccttgctctctgccgc
ggtgtccccctggaggaagtggcgaagaagatcagtttcaaggattgcatcccacgttcc
ttccgtcggcagatccggcagcacgatgtgttgacaaggctgcgcctgcggaccatcttc
caccggttcctgcgggacttccagccaggccgcctctcccagcaggtcgtcatggtcaag
tacctggccactctcgagtgcttggcaccccgcttcggcacagagcgcatgccagtgtac
cagttggagctgctgacccagactgcaggagcaccctgctacattcgggacagtgggcag
gcccttctagagcccacaccagcatccgctgccagaccccccacccatgaggtgctagtg
accggcactggcggcatccagtggcggccattactagcagtgggtcccagcagcagtgtc
aggaatcgccctgctggcccagctggaaagaaagctaaggcgcatgaggggagcaaccag
ccagcagacaagccacgggaggcacagtggacctacttctgtgacttccgagacatcacc
cacatggtgctgaaagagtgccacgtcagcatccgctgccaggacaagttcttggagttg
gccctgccttcccgggctgctgccctgtccttagtgtcgctgctagatggctatttccgc
ctgacatctgactcaagccattatctgtgccatgaagtggctcccccgcggcttgtgatg
agcatccaggagggtatccacggacccctgctggagccatttgtgctagccaagctgcgc
ccggaggatggcctctacctcatccactggagcaccacccacttcaaccgccttatcctc
acggtggcccagcatgaccaggcgtccagtgccaagagttggcgcctacgcaagttcccc
attgagctgcaggctggggcctttacactggagggctgggaccggtccttccccagtgtg
cgggatctgcgggctgccctgcagggctgttcactgcggtctggccaagactgcttctcc
ctgcaccgctgctgtctgccacagccaggagagttctccaatcttgttatcctgcggggg
tcttgcgccagcaccaggccacccaacctcagccatctcagcttccaccgagtcagctgg
gacaagatcacccggctatcccacttgggccagggaaccaggaccaatgtgtatgagggc
ctcttactagtcacagacagaggccccgaggaggacaaggcagatgatgggggccctggg
caggacctgcgagtggtactcaaggtgctggaccccagccaccacaacattgccctggcc
ttctatgagactgccagcctcatgagccaggtctcccatgtacacctggcctttgtacat
ggcgtctgtgtgcatggctcagagaacatcatggtgactgagtatgtggaacacgggccc
ttggatgtctgcctgcggcgggaaaggggccatgtgcctgtggcctggaaggtggtggta
gcccagcagctggccagtgccctcagctacctggaagacaagagcctagttcatggaaat
gtgtgtggccggaacattcttctggcgcgtttggggctggtagagggcaccagccctttc
atcaagctgagcgaccccggtgtgggcctgggggccctctccagggaggagcgggtagag
aggatcccctggatagctcccgagtgtttgtctggtgtggacagcagcctcagtactgca
gctgacaagtggggctttggtgccaccctcctggagatctgcttcgatggggagatcctc
ctgcagggccgtggcccctctgagaaagagcacttctaccagaagcagcaccagctgccc
cagccttcctccccagaactggcggtgcttaccagccaatgcctgaactatgagccaggc
cagcggccatccttccgcaccatcctgcgggacctcactcgactgcagccccaaaatctc
gatgtttctgcggtgaatccggactcaccaacttcagattccaccgttttccacaagcgc
tatttgaaaaaaatcagggacctgggcgagggtcactttggcaaggtcagcctgtattgc
tacgacccgaacaacgatgggactggcgagatggtggccgtgaaggccctcaaagcaggt
tgcagcccccagctcctccccggctggacacgagagattgacatattgcgcacgttgtac
cacaagcacatcgtcaagtacaagggctgctgcggggatcaaggggagaagtcagtgcag
cttgtcatggagtatgtgcctctgggcagcctccgagactacctaccccggcacagtgtt
gggctggcccagctgttgctcttcgctctgcagatctgtgagggcatggcctacctgcac
tcgcagcactacatccaccgagacctggctgcccgcaatgtgctgttggacaatgacaag
ctggtcaagattggggactttggcctagccaaggccgtgcctgaaggccacgaatactac
cgcgtccacgaggatggggatagccccgtgttctggtatgccccagagtgtctgaaggaa
tgtaaattctactatgcatctgatgtctggtcctttggggtcaccatgtatgagctgctg
acccactgtgactccagccagagccctccatcgaaattcattgaactcataggcctcaac
cagggccagaggacagtgctgaggcttactgaactgttggaacaaggggaacggctgcct
cagccagacaaatgtccctgtgagatctatctcctcatgaagaactgctgggaggcagag
gcctcatttcgcccgaccttccaaaatctcatccccatcctcaagacagtccacgagaaa
taccaaggtcaggccccttcggtgttcagtgtatgctga
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integrated database retrieval system
