KEGG   Talpa occidentalis (Iberian mole): 119241194
Entry
119241194         CDS       T07495                                 
Symbol
PTGS2
Name
(RefSeq) prostaglandin G/H synthase 2
  KO
K11987  prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
Organism
tod  Talpa occidentalis (Iberian mole)
Pathway
tod00590  Arachidonic acid metabolism
tod01100  Metabolic pathways
tod04064  NF-kappa B signaling pathway
tod04148  Efferocytosis
tod04370  VEGF signaling pathway
tod04625  C-type lectin receptor signaling pathway
tod04657  IL-17 signaling pathway
tod04668  TNF signaling pathway
tod04723  Retrograde endocannabinoid signaling
tod04726  Serotonergic synapse
tod04913  Ovarian steroidogenesis
tod04921  Oxytocin signaling pathway
tod04923  Regulation of lipolysis in adipocytes
tod05010  Alzheimer disease
tod05022  Pathways of neurodegeneration - multiple diseases
tod05140  Leishmaniasis
tod05163  Human cytomegalovirus infection
tod05165  Human papillomavirus infection
tod05167  Kaposi sarcoma-associated herpesvirus infection
tod05200  Pathways in cancer
tod05204  Chemical carcinogenesis - DNA adducts
tod05206  MicroRNAs in cancer
tod05222  Small cell lung cancer
Brite
KEGG Orthology (KO) [BR:tod00001]
 09100 Metabolism
  09103 Lipid metabolism
   00590 Arachidonic acid metabolism
    119241194 (PTGS2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04370 VEGF signaling pathway
    119241194 (PTGS2)
   04064 NF-kappa B signaling pathway
    119241194 (PTGS2)
   04668 TNF signaling pathway
    119241194 (PTGS2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    119241194 (PTGS2)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    119241194 (PTGS2)
   04657 IL-17 signaling pathway
    119241194 (PTGS2)
  09152 Endocrine system
   04923 Regulation of lipolysis in adipocytes
    119241194 (PTGS2)
   04913 Ovarian steroidogenesis
    119241194 (PTGS2)
   04921 Oxytocin signaling pathway
    119241194 (PTGS2)
  09156 Nervous system
   04726 Serotonergic synapse
    119241194 (PTGS2)
   04723 Retrograde endocannabinoid signaling
    119241194 (PTGS2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    119241194 (PTGS2)
   05206 MicroRNAs in cancer
    119241194 (PTGS2)
   05204 Chemical carcinogenesis - DNA adducts
    119241194 (PTGS2)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    119241194 (PTGS2)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    119241194 (PTGS2)
   05167 Kaposi sarcoma-associated herpesvirus infection
    119241194 (PTGS2)
   05165 Human papillomavirus infection
    119241194 (PTGS2)
  09174 Infectious disease: parasitic
   05140 Leishmaniasis
    119241194 (PTGS2)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    119241194 (PTGS2)
   05022 Pathways of neurodegeneration - multiple diseases
    119241194 (PTGS2)
Enzymes [BR:tod01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.99  Miscellaneous
    1.14.99.1  prostaglandin-endoperoxide synthase
     119241194 (PTGS2)
SSDB
Motif
Pfam: An_peroxidase EGF EGF_2
Other DBs
NCBI-GeneID: 119241194
NCBI-ProteinID: XP_037362216
LinkDB
Position
Unknown
AA seq 604 aa
MLFRSLLLCAALALSSAANPCCSNPCQNRGVCMTIGFDRYKCDCTRTGFYGENCSTPELM
TRIKLLLKPTPNTVHYILTHFRGFWNIVNNIPFLRNAIMKYVLTSRSHLVESPPTYNMHY
GYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGKKKLPDSKEIVEKFLLRRKFIPDPQGT
NMMFTFFAQHFTHQFFKTDHKRGPAFTKGLGHGVDLSHVYGETLDRQHKLRLFKDGKMKY
QIIDGEVYPPTVKDTQVSMIYPPQVPEHLRFAVGQEVFGMVPGLMMYATIWLREHNRVCD
VLKKEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYNFKLKFDPELLFNQQFQYQ
NRIAAEFNTLYHWHPLLPDAFQIDEKEYNYQQFLYNNSILLEHGLTQFVESFSRQIAGRV
AGGRNLSPAVQKVAQASIDQSRQMKYQSFNEYRKRFLLQPYKSFEELTGEKEMAAELEAA
YGDIDAMELYPALLVEKPRPDAIFGETMVELGAPFSLKGLMGNPICSPEYWKPSTFGGEV
GFKIINTASIQSLICYNVKGCPFTSFSVQDPQLTKTVTINASSSHSGLDDINPTVLLKER
STEL
NT seq 1815 nt   +upstreamnt  +downstreamnt
atgctcttccgctccctgcttctctgcgcggcgctggcgctcagcagcgcagcaaatcct
tgctgttccaacccatgtcaaaaccgaggtgtgtgtatgactataggatttgaccggtat
aagtgtgactgtacccgaaccggattttatggcgaaaactgttcaacgcctgaattaatg
acaagaataaaattattgctgaaacctactccaaatacagtgcactacatacttacccac
ttcaggggtttctggaacattgtcaataacattcccttcctgcggaacgcaattatgaaa
tatgtgttgacatccagatcacatttggttgagagcccaccaacttacaacatgcactac
ggctacaaaagctgggaggccttttctaacctctcctattataccagagctcttcctcca
gtacctgatgactgtccaactcccatgggtgtgaaaggaaagaaaaagcttcctgattcc
aaagaaattgtggaaaaattccttttaagaagaaagttcatccctgatcctcagggcaca
aatatgatgtttacattctttgctcagcacttcacccaccaattcttcaaaacagatcat
aagcgaggaccagctttcaccaaaggactgggccatggggtggacttaagtcatgtttac
ggcgaaactttggatagacagcataaactgcgccttttcaaggatggaaaaatgaaatat
cagataattgatggagaagtgtatcctcccacagtcaaagatactcaggtctcaatgatc
tacccacctcaagtccctgaacatctccgctttgctgtggggcaggaggtctttggcatg
gtgcctggtctgatgatgtatgccaccatttggctgcgggaacataacagagtatgtgat
gtgctgaaaaaggaacatccagaatggggtgatgagcagttattccagacaagcaggcta
atactgataggtgaaactattaagattgtgattgaagactatgtccaacacttgagtggc
tataacttcaagcttaaatttgatccagaactgcttttcaaccaacaattccaataccaa
aaccgcattgctgctgagtttaacaccctctaccactggcatccccttctgcctgacgcc
tttcaaattgacgaaaaagagtacaactatcaacagtttctctacaacaactctatctta
ttagaacatggtcttacccagtttgttgaatcattcagcaggcaaattgctggcagggtt
gctggtggtaggaatctttcacctgcagtacagaaagtagcacaggcctcaattgaccag
agcagacagatgaaataccagtcttttaatgagtatcgcaagcgctttttgctacagccc
tacaaatcctttgaagaactcacaggtgagaaggaaatggctgcggagttagaagcagcc
tatggtgatatcgatgctatggaactgtatcctgctcttctggtagaaaagccacgtcca
gatgccatctttggtgagaccatggtagaacttggagcaccattctctttgaaaggactt
atgggtaatcctatttgctctcctgagtactggaagcctagtacttttggtggggaagta
ggttttaagatcatcaacactgcctcaatccagtctctcatctgctataatgtgaagggc
tgtccttttacctcattcagtgttcaagatccacagctgaccaaaacagtcaccattaat
gcaagttcttctcactctggactagatgacatcaaccccaccgtactactaaaagaacgt
tcaactgaactatag

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