Talpa occidentalis (Iberian mole): 119241983 Help Entry 119241983         CDS       T07495                                  Symbol ADCY9 Name (RefSeq) adenylate cyclase type 9   KO K08049   adenylate cyclase 9 [EC:4.6.1.1] Organism tod  Talpa occidentalis (Iberian mole) Pathway tod00230   Purine metabolism tod01100   Metabolic pathways tod01522   Endocrine resistance tod04015   Rap1 signaling pathway tod04020   Calcium signaling pathway tod04022   cGMP-PKG signaling pathway tod04024   cAMP signaling pathway tod04062   Chemokine signaling pathway tod04072   Phospholipase D signaling pathway tod04081   Hormone signaling tod04082   Neuroactive ligand signaling tod04114   Oocyte meiosis tod04211   Longevity regulating pathway tod04213   Longevity regulating pathway - multiple species tod04261   Adrenergic signaling in cardiomyocytes tod04270   Vascular smooth muscle contraction tod04371   Apelin signaling pathway tod04540   Gap junction tod04611   Platelet activation tod04713   Circadian entrainment tod04714   Thermogenesis tod04723   Retrograde endocannabinoid signaling tod04724   Glutamatergic synapse tod04725   Cholinergic synapse tod04727   GABAergic synapse tod04750   Inflammatory mediator regulation of TRP channels tod04911   Insulin secretion tod04912   GnRH signaling pathway tod04913   Ovarian steroidogenesis tod04914   Progesterone-mediated oocyte maturation tod04915   Estrogen signaling pathway tod04916   Melanogenesis tod04918   Thyroid hormone synthesis tod04921   Oxytocin signaling pathway tod04923   Regulation of lipolysis in adipocytes tod04925   Aldosterone synthesis and secretion tod04926   Relaxin signaling pathway tod04927   Cortisol synthesis and secretion tod04928   Parathyroid hormone synthesis, secretion and action tod04934   Cushing syndrome tod04935   Growth hormone synthesis, secretion and action tod04961   Endocrine and other factor-regulated calcium reabsorption tod04962   Vasopressin-regulated water reabsorption tod04970   Salivary secretion tod04971   Gastric acid secretion tod04972   Pancreatic secretion tod04976   Bile secretion tod05032   Morphine addiction tod05163   Human cytomegalovirus infection tod05166   Human T-cell leukemia virus 1 infection tod05200   Pathways in cancer tod05207   Chemical carcinogenesis - receptor activation tod05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:tod00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     119241983 (ADCY9)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     119241983 (ADCY9)    04371 Apelin signaling pathway     119241983 (ADCY9)    04020 Calcium signaling pathway     119241983 (ADCY9)    04072 Phospholipase D signaling pathway     119241983 (ADCY9)    04024 cAMP signaling pathway     119241983 (ADCY9)    04022 cGMP-PKG signaling pathway     119241983 (ADCY9)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     119241983 (ADCY9)    04081 Hormone signaling     119241983 (ADCY9)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     119241983 (ADCY9)   09144 Cellular community - eukaryotes    04540 Gap junction     119241983 (ADCY9)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     119241983 (ADCY9)    04062 Chemokine signaling pathway     119241983 (ADCY9)   09152 Endocrine system    04911 Insulin secretion     119241983 (ADCY9)    04923 Regulation of lipolysis in adipocytes     119241983 (ADCY9)    04912 GnRH signaling pathway     119241983 (ADCY9)    04913 Ovarian steroidogenesis     119241983 (ADCY9)    04915 Estrogen signaling pathway     119241983 (ADCY9)    04914 Progesterone-mediated oocyte maturation     119241983 (ADCY9)    04921 Oxytocin signaling pathway     119241983 (ADCY9)    04926 Relaxin signaling pathway     119241983 (ADCY9)    04935 Growth hormone synthesis, secretion and action     119241983 (ADCY9)    04918 Thyroid hormone synthesis     119241983 (ADCY9)    04928 Parathyroid hormone synthesis, secretion and action     119241983 (ADCY9)    04916 Melanogenesis     119241983 (ADCY9)    04925 Aldosterone synthesis and secretion     119241983 (ADCY9)    04927 Cortisol synthesis and secretion     119241983 (ADCY9)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     119241983 (ADCY9)    04270 Vascular smooth muscle contraction     119241983 (ADCY9)   09154 Digestive system    04970 Salivary secretion     119241983 (ADCY9)    04971 Gastric acid secretion     119241983 (ADCY9)    04972 Pancreatic secretion     119241983 (ADCY9)    04976 Bile secretion     119241983 (ADCY9)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     119241983 (ADCY9)    04961 Endocrine and other factor-regulated calcium reabsorption     119241983 (ADCY9)   09156 Nervous system    04724 Glutamatergic synapse     119241983 (ADCY9)    04727 GABAergic synapse     119241983 (ADCY9)    04725 Cholinergic synapse     119241983 (ADCY9)    04723 Retrograde endocannabinoid signaling     119241983 (ADCY9)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     119241983 (ADCY9)   09149 Aging    04211 Longevity regulating pathway     119241983 (ADCY9)    04213 Longevity regulating pathway - multiple species     119241983 (ADCY9)   09159 Environmental adaptation    04713 Circadian entrainment     119241983 (ADCY9)    04714 Thermogenesis     119241983 (ADCY9)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     119241983 (ADCY9)    05207 Chemical carcinogenesis - receptor activation     119241983 (ADCY9)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     119241983 (ADCY9)    05163 Human cytomegalovirus infection     119241983 (ADCY9)   09165 Substance dependence    05032 Morphine addiction     119241983 (ADCY9)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     119241983 (ADCY9)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     119241983 (ADCY9)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     119241983 (ADCY9) Enzymes [BR:tod01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      119241983 (ADCY9) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N Adcy_cons_dom Motif Other DBs NCBI-GeneID:  119241983 NCBI-ProteinID:  XP_037363597 LinkDB All DBs Position Unknown AA seq 1352 aa AA seqDB search MASPPHQQLLQHHGTEVSCDSSGDSNSVRVKIHPKQLSSGSQPKRCKYSISSSCSSSGDS GGAPRRVGGGRLRRQRRLPQLFERASSRWWDPRFDSVNLEEACLERCFPQTQRRFQCALF YVGFACLLWSVYFVVHMRARLTVTAAPALCLLVLCVGFFLFTFTKLYARHYVWTSLALTL LVCALTLAAQFQALTPDWGRLDSSNHTPPAQPADTCLSQVGSFSMCIEVLLLLYTVMHLP LYLSVFLGVAYSVLFETFGYHFRNEDCFPSPGAGAWHWELVSRALLHVCIHAIGIHLFIM SQVRSRSTFLKVGQSIMHGKDLEVEKALKERMIHSVMPRIIADDLMRQGDEESESSVRRH ATASPKNRKKKSSIQKAPIAFRPFKMQQIEEVSILFADIVGFTKMSANKSAHALVGLLND LFGRFDRLCEETKCEKISTLGDCYYCVAGCPEPRADHAYCCIEMGLGMIRAIEQFCQEKK EMVNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISEATAKYLDD RYEMEDGKVFERLGQSVVADQLKGLKTYLIAGQRAKEPRCSCSEALLSGLEVIDGSRVSS GPRGQGTASPGSVSDLAQTVKTFDNLKTCPSCGITFAPKSEAGAEGGTVQNGCQEEQKSS TKASGGPTSKTQNGLLSPPQEEKLTNSQTSLCEILQEKGKWAGVSLDQSALLPLRFKNIR EKTDAHFVDVIKEDSLMKDYFFKPPINQFSLNFLDRELERAYRSSYQQEVAKSSPAKTFA SATFSSLLDVFLSTTVFLILSTTCFLKYGASSTPPPPAALGVFGAALLLEVLSLVVSIRM VFFPEAVMACTKHLLEWVSGWVPRHLLGAVLVSLPALAVYSHVTSEFQTDSHFTVFAGSA VLVAVVHYCNFCQLSSWMRSSLATVVGAGPLLLLYVSLCPDSSIVMSHLDAAQNFSSERT RCNNSLPRNGRLQASLLGQEVILVFFLLLLLVWFLNREFEVSYRLHYHGDVEADLHRTKI QSMRDQADWLLRNIIPYHVAEQLKVSQTYSKNHDCGAVIFASVVNFSEFYEENYEGGKEC YRVLNELIGDFDELLGKPAYGGIEKIKTIGATYMAAAGLNATQAQDGGHPQGHLQLLFEF AREMMRVVDDFNNNMLWFNFKLRVGFNHGPLTAGVIGTTKLLYDIWGDTVNIASRMDTTG VECRIQVSEESYRVLSKMGYDFDYRGTVNVKGKGQMKTYLYPRCTDSGLVPQHQLSISPD IRVQVDGSIGRSPTDEIASLVPSVQSSDRASLGSDSGAPAKDPQPPAKRPWRDPGRAEER CRFGRAVGKADHEDTGLEDANELTRLDVSKGV NT seq 4059 nt NT seq  +upstreamnt  +downstreamnt atggcttccccgccccaccagcagctgctgcagcaccacggcaccgaggtgagctgcgac tccagcggcgacagcaacagcgtgagggtgaaaatccaccccaagcagctgtcctccggc agccagcccaagcgctgcaagtacagcatctcctccagctgcagcagctccggggactcc ggcggggcgccccgcagggtgggcggcggccgcctgcgccggcagaggcggctgccccag ctgttcgagcgcgcctccagccgctggtgggacccgaggttcgactcggtgaacctggag gaggcttgcctggagcgctgcttcccgcagacccagcgccgcttccagtgcgcgctcttc tacgtgggcttcgcctgcctgctgtggagcgtctacttcgtggtgcacatgagggccagg ctgacggtcacggcggcccccgcgctgtgcctcctcgtgctgtgcgtgggcttttttctg tttaccttcaccaagctgtacgcgcgccactacgtgtggacctcgctggcgctcaccctc ctggtgtgcgccctgaccctggccgcccagttccaggccttgacgcctgactggggccgc ctggacagctccaaccacacgccccccgcccagcccgcagacacttgcctgtctcaggtg gggagcttctccatgtgcatcgaggtgctgcttctgctctacaccgtcatgcacctgcct ttgtacttgagtgtgtttttgggggtggcctattccgttcttttcgagacctttggctat cacttccgaaacgaagactgcttcccctcgcctggggcgggggcctggcactgggagctg gtgagccgggccctgctccacgtctgcatccacgccatcggcatccacctgttcatcatg tcccaggtgaggtcccggagcaccttcctcaaggtgggccagtcaatcatgcacgggaag gacctggaagtggaaaaagccctcaaggagaggatgatccactccgtgatgcccaggatc atagccgacgacctgatgcgacagggcgatgaggagagcgagagctccgtcagaaggcac gccaccgccagccccaagaaccggaagaagaagtcctccatccagaaggcccccatcgcc ttccgccccttcaagatgcagcagatcgaggaagtcagcattttgttcgcggacatcgtg ggcttcaccaagatgagtgccaacaagtcagcgcatgccctggtgggcctcctcaacgac ctgttcgggcgcttcgaccgcctgtgcgaggagaccaagtgcgagaagatcagcacgctg ggggactgctactactgcgtggccggctgccccgagccccgcgccgaccacgcctattgc tgcatcgagatgggcctgggcatgatccgcgccatcgagcagttctgccaggagaagaag gagatggtgaacatgcgcgtgggggtgcacacgggcaccgtcttgtgcggcatcttgggc atgaggcggtttaagttcgacgtgtggtccaacgacgtgaacctggccaacctcatggag cagttgggagtggccggcaaggtccacatttccgaggccaccgccaaatacctagatgat cggtacgaaatggaggacggcaaagtctttgagcgtctggggcagagcgtcgtggccgac cagttgaaaggtttgaagacatacctgatagcgggtcagagagcgaaggagcctcgttgc agctgctcagaggccttgctttctggcctcgaggtcattgacggctcacgggtgtcctca ggccctaggggacaggggacagcgtcgccagggagtgtcagtgacttggcacagactgtc aaaacctttgataaccttaagacctgcccttcgtgtggaatcacgtttgcgcccaagtca gaagcaggtgccgaaggagggacagtccagaatggctgtcaagaggagcagaaaagcagc accaaggcttccggagggcctacttccaaaactcagaacggcctgctgagcccaccccag gaggagaagcttaccaacagccagacctcgctgtgtgagatcctacaggagaaggggaag tgggcgggcgtgagcctggaccagtctgctctcctgcccctgagattcaagaacatccgg gaaaagacagatgcccattttgtggatgttatcaaggaagacagcctgatgaaagattat ttttttaagccacccattaaccagttcagcttgaacttcctggaccgggagctggagcgc gcctataggagcagctatcaacaagaggtggcgaagagctctcccgcgaagaccttcgcc agcgccaccttcagctccctcctggacgtgtttctgtcaaccaccgtgtttctgattctc tccactacctgcttcctgaaatatggggcctccagcacaccgccccctcctgctgccctt ggggtcttcggggcggccctgctgctggaggtgctgtccctggtggtttccatcaggatg gtgttcttccctgaggccgtcatggcctgcaccaagcacctgctggagtgggtctccggc tgggtcccacgccacctcctcggggctgtcctggtctcgctccccgctctggctgtctac tcacacgtcacctccgaattccagacagactcacacttcactgtcttcgcgggctccgcc gtcctggtggccgtggtgcactactgcaacttctgccagctcagctcctggatgcggtcc tccctggccacagtcgtgggcgccgggcccctcctcctgctctacgtctccctgtgcccg gacagttccatcgtgatgtcacacctcgatgcagcacagaacttcagttccgagaggacc cggtgcaacaactccctgccgcggaatggccggcttcaggccagcctgcttggccaggag gtgatcctcgtcttcttcctcctgctcctgctggtctggttcctgaaccgggagttcgag gtcagctaccgcctgcactaccacggcgacgtggaggctgaccttcaccgcaccaagatc cagagcatgcgggaccaggccgactggctgctgcggaacatcatcccctaccacgtggcc gagcagctcaaggtgtcccagacctactccaagaaccacgactgcggggccgtcatcttc gccagcgtcgtcaacttcagcgagttctacgaggagaactacgagggcggcaaggagtgc taccgcgtcctcaacgagctcatcggggacttcgacgagctgctgggcaagccggcctac ggcggcatcgagaagatcaagaccatcggggccacgtacatggccgcggcggggctgaac gccacgcaggcacaggacggcggccacccgcagggccacctgcagctgctgttcgagttc gccagggagatgatgcgcgtggtggacgacttcaacaacaacatgctctggttcaacttc aagctgcgcgtgggcttcaaccacgggcccctcacggccggcgtcatcggcaccaccaag ctgctgtacgacatctggggggacacggtcaacatcgccagcaggatggacaccaccggc gtggagtgccgcatccaggtgagcgaggagagctaccgcgtcctgagcaagatgggctac gacttcgactaccggggcaccgtgaatgtcaagggcaagggccagatgaagacctacctg taccccaggtgcacggacagcggactcgtgccccagcaccagctgtccatctccccggac atccgcgtccaggtggacggcagcatcgggcggtcccccacggacgagatcgccagcctg gtgccttctgtccagagctccgacagggcctcgctgggctctgacagcggcgcgccagcc aaggacccccagccgcccgccaagcggccgtggagggaccccggcagggccgaagagagg tgccggtttggcagagccgtcgggaaggccgaccacgaggacacagggctggaggatgcc aacgagctcacccggctcgacgtctccaagggcgtgtga

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