Talpa occidentalis (Iberian mole): 119242027 Help Entry 119242027         CDS       T07495                                  Symbol TSC2 Name (RefSeq) tuberin isoform X1   KO K07207   tuberous sclerosis 2 Organism tod  Talpa occidentalis (Iberian mole) Pathway tod04072   Phospholipase D signaling pathway tod04115   p53 signaling pathway tod04140   Autophagy - animal tod04150   mTOR signaling pathway tod04151   PI3K-Akt signaling pathway tod04152   AMPK signaling pathway tod04211   Longevity regulating pathway tod04218   Cellular senescence tod04714   Thermogenesis tod04910   Insulin signaling pathway tod04919   Thyroid hormone signaling pathway tod05163   Human cytomegalovirus infection tod05165   Human papillomavirus infection tod05168   Herpes simplex virus 1 infection tod05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:tod00001]  09130 Environmental Information Processing   09132 Signal transduction    04072 Phospholipase D signaling pathway     119242027 (TSC2)    04151 PI3K-Akt signaling pathway     119242027 (TSC2)    04152 AMPK signaling pathway     119242027 (TSC2)    04150 mTOR signaling pathway     119242027 (TSC2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     119242027 (TSC2)   09143 Cell growth and death    04115 p53 signaling pathway     119242027 (TSC2)    04218 Cellular senescence     119242027 (TSC2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     119242027 (TSC2)    04919 Thyroid hormone signaling pathway     119242027 (TSC2)   09149 Aging    04211 Longevity regulating pathway     119242027 (TSC2)   09159 Environmental adaptation    04714 Thermogenesis     119242027 (TSC2)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     119242027 (TSC2)   09172 Infectious disease: viral    05168 Herpes simplex virus 1 infection     119242027 (TSC2)    05163 Human cytomegalovirus infection     119242027 (TSC2)    05165 Human papillomavirus infection     119242027 (TSC2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01009 Protein phosphatases and associated proteins [BR:tod01009]     119242027 (TSC2) Protein phosphatases and associated proteins [BR:tod01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      119242027 (TSC2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Tuberin DUF3384 Rap_GAP Cnd1 Motif Other DBs NCBI-GeneID:  119242027 NCBI-ProteinID:  XP_037363678 LinkDB All DBs Position Unknown AA seq 1789 aa AA seqDB search MAKPAGKDSGLREKFKTLLGLGTPRPHPRSAEGKHTEFVITGEILRELSIECGLNNRIRT IGQICEVAKTKKFEEHAVEALWKAVADLLQPERPPEARHAVLALLKAIVQGQGDRLGILR ALFFRVIRDYPSNEDLHERLEVFKALTDNGRHITYLEEELAEFVLQWMDVGLSSEFLLVL VNLVKFNSCYLDEHISAMVNMICLLCVQTVSSVDIEVSLQVLDAVVCYNRLPAESLPLFL VTLCRTVNVKELCEPCWKLMRNLLGTHLGHSAICNMCRVMEDRAYMEDAPLLRGAVFFVG MALWGAHRLYSLKNSPTSVLPSFYEAMTCPNEVVSYEIVLSITRLVKKYRRELQAVTWDI LLRIMERLLQQLQCLDSPELRAIVHDLLTTVEELCDQNEFHGSQERYFELVERCADQRPE SSLLNLITYRAQSIHPAKDGWIRSLQALMERFFRSECRSAVRIKALDVLSFVLLINRQFY EEELINSVVISQLSHIPEDRDPQVRKLATQLLVDLAEGCHTHHFNSLLDIIEKVIARSLS PPPELEERDVAAYSASLEDVKTAVLGLLVILQTKLYALPAGHATRVYEMLVGHLQLHYVH SYTLPVASSIRLRAFDFLLLLRADSLHRLGLPSKDGLVRFSPYCLCDSACVEPERGPEKK TSGPLSPPTGPPSPATPGPAVRLASLPYSLLFRVLLWCLKQETDWKVLKLVLSKLPEALR YKVLIFTSPCSVDQLSSALCAMLSVPKTLERLRGTPEGFSRTDLHLAVVPVLTALISYHG YLDKARQREMVYCLEQGLIFRCASQCVVALAICSVEMPDIMVKALPVLVVKLTHISATAS MAIPLLEFLSTLARLPHLYRNFAAEQYASVFAIALPYTNPSKFNQYIVCLAHHVIAMWFI RCRLPFRKDFVPFITKGLRSNVLMSFDDTPEKDSFRARSTSLNERPKSLRVARPPKQGLN NSPPVKELKESSAAEAFRCRSVSVSEHAARRIHTSLTSASLGSADESSVAQADDSLKNLH LELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRS LLGLDSGELQGSPDLSSDPGARVRHTKEAPAKLESQAGQQVGRGARDRVRSMSGGHGLRV GALDAPASHFPCGPTSPGSQTVPASRPEVPEGSPHPARRKTNLAAYVPLLTQGWAEILVR RPTGNTSWLMSLENPLSPFSSDIDNMPLQELSNALMAAERFKERRDTALYKSLSMPAAGS AKPPPPPRSNTDSAVVLEEGNAGGVHLAAEPPDLEDFEATPGVDRRCERATDYSRSSSTS SQEEKSFRGEEPAAGGIPIERAVSSEGARPTADLAFQPSQPLSKSSSSPELQSLQDVLGD PGDKADLGRLSPEAKARSQSGTLDGESASWSASGADSQGLGPPQPEGPSPASCPRSPSGL RPRGYTISDSAPSRRGKRVERDALKSRAGAANAEKVPGINPSFVFLQLYHSPFFGDESNK PILLPNETFERSVQLLDQIPSYDTHKIAVLYVGEGQSSSELAILSNEHGSYRYTEFLTGL GRLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFHIATLMPTKDGDRQRCDKK RHLGNDLVSIVYNDSGEDFKLGTIKGQFNFVHVIITPLDYECNLVSLQCRKDMEGLVDTS VAKIVSDRNLPFVARQMALHANMASQVHHSRSNPTDVYPSKWIARLRHIKRLRQRVREEA HYAHPSLPLVHLPGHAKAPAQAPAEPTPAHETGQRRRLISSVDDFTEFV NT seq 5370 nt NT seq  +upstreamnt  +downstreamnt atggccaagcccgccggcaaagactcgggcctgagggagaagttcaagactctgctgggc ctgggcaccccgcggccgcacccccggtctgcggagggcaagcacacggagttcgtcatc accggcgagatcctgagggaactcagcatcgagtgtggtctcaacaatcgcatccgaacg atagggcagatctgtgaagttgcaaaaactaagaaatttgaagagcacgcggtggaggcg ctctggaaggccgtcgcggacctgctgcagccggagcggccgccggaggcccggcacgcg gtgctggccctgctcaaggccatcgtgcaggggcagggcgaccgcctgggcatcctccgg gccctcttcttcagggtcatcagggactacccctccaacgaggacctccacgagcggctg gaagtgttcaaggcgctcacagacaacgggaggcacatcacctacttggaggaagagctg gccgagtttgtcctgcagtggatggatgtcggtctgtcctcggagttcctcttggtgctc gtgaacctggtcaagttcaacagctgttacttggacgagcacatctcggcaatggtgaac atgatctgcctgctgtgtgtccagaccgtgtcttccgtggacatagaggtatcgctgcag gtgctggacgccgtggtctgctacaaccgcctgcccgccgagagcctcccgctcttcctc gtcacgctctgccgcaccgtgaacgtcaaggagctctgcgagccctgctggaagctgatg cgtaacctcctgggcacccacctgggccacagtgccatctgcaacatgtgccgcgtcatg gaggacagagcgtacatggaggacgccccgctgctaaggggagccgtgttctttgtcggc atggcgctctggggggcccaccgactctattcccttaagaactccccgacatcagtgttg ccgtctttctacgaggccatgacctgccccaacgaggtggtgtcctacgagatcgtcctt tccatcaccaggctcgttaagaagtacaggcgggagctgcaggctgtgacgtgggacatc ctgctgcgcatcatggagcgcctgctgcagcagctgcagtgcctggacagcccggagctc agggccattgtccacgatctgctcaccacggtggaggagttgtgtgaccagaacgagttc cacggctcacaggagagatactttgagctcgttgagagatgtgcggaccagaggccggag tcgtccctcctgaacctgatcacctatagagctcagtccatccaccccgccaaggacggc tggatccgcagcctacaggcgctgatggagaggttcttcaggagcgagtgccgcagcgct gtgcggatcaaggcgttggatgtgctgtctttcgtgctgctcatcaaccggcagttctat gaggaggagctcatcaactccgtggtcatctcgcagctctcccacatccctgaggacagg gacccccaggtgcggaagctggctactcagctgctggtggacctggctgagggctgccac acgcaccacttcaacagcctgctggacatcatcgagaaggtgatcgcccgctcgctctcg ccaccccccgagctggaggagcgggacgtggctgcctactcggcctccctggaggatgtg aagacggcggtcctggggctcctggtcatcctccagaccaagctctacgccctgcctgcc ggccacgccacccgcgtctacgagatgctggtcggccacctgcagctgcactacgtgcac agctacaccctgcccgttgccagcagcatccggctgcgggccttcgacttcctgctgctg ctgcgcgcggactcactgcaccgcctgggcttgcccagcaaggacggactcgtgcgcttc agcccctactgcctctgcgactccgcgtgcgtggagcctgagcggggccctgagaagaag accagcggccccctgtcgcctcccaccgggcctcccagccccgcgacgccgggcccggct gtgcgactggcctccctgccctactccctgctgttccgtgtgctgctgtggtgcttgaag caggagaccgactggaaggtgctgaagctggtgctgagcaagctgcctgaggcgctgcgc tacaaggtcctcatcttcacctcaccctgcagcgtggaccagctgtcctctgccctctgc gccatgctttcagttcccaagacactcgagcggctgcgaggcaccccggaaggcttctcc agaactgacctgcacttggccgtggtccccgtactgacggccttgatctcctaccacggc tacttggacaaggccaggcagcgggagatggtgtactgcctggagcaaggcctcatcttc cgctgcgccagccagtgcgtggtggcgctagccatctgcagcgtggagatgcccgacatc atggtcaaggcgctgcccgtgctggtggtgaagctcacgcacatctccgccacggccagc atggccatccccctgctggagttcttgtccactctggccaggctgccgcacctctacagg aacttcgcggccgagcagtacgccagcgtgtttgccatcgccctgccctacaccaacccc tccaagttcaaccagtacatcgtgtgcctggcccaccacgtcatcgctatgtggttcatc aggtgccgcctgcccttccgcaaggacttcgtccccttcatcaccaagggcctgcgctcc aacgttctcatgtccttcgacgacacccccgagaaggacagcttcagagcccggagcacc agtctcaacgagaggcccaagagtttgagggtagccaggccccccaaacaaggcctgaac aactccccacccgtgaaagaactcaaggagagctctgcagccgaggccttccggtgccgc agcgtcagtgtgtctgaacacgcggcccgcaggatacacacgtccctcaccagcgccagc ctggggtctgcggacgagagctccgtggcccaggccgacgacagcctgaagaacctccac ctggagctcacggagacgtgtctggacatgatggcccgatacgtgttctccaacttcacg gcggtgcccaagaggtccccggtgggagagttccttctggccggcggcaggaccaagact tggctggtcgggaataaactggtcaccgtgacaaccagtgtgggcaccggaacccgctcc ctgctgggcctggactcgggcgagctgcagggcagcccggacctgagctccgaccccggc gcacgtgtgcgccacacgaaggaggcgccagccaagctggagtcccaggctgggcagcag gtgggccgcggggcccgggaccgggtgcgctccatgtccgggggccacggcctgcgagtt ggtgccctggacgccccagcttcccacttcccctgcggccccacttccccgggatcacag accgtgccagccagccggcccgaagtgcccgagggctccccgcatccggcgcggaggaag acaaacctggcggcctacgtgcccctgctgacccagggctgggcagagatcctggtccgc aggcccacagggaacaccagctggctgatgagtttggagaacccgctgagccccttctcc tcggacatcgacaacatgcccctgcaggagttgtccaacgccctcatggccgccgagcgc ttcaaggagcggcgcgacacggccctgtacaagtcgctgtccatgcccgccgctggctct gccaagccgcccccgcccccgcgctccaacacagactctgccgtggtcctggaggaggga aatgctggcggggtgcacctggccgctgagcccccggacctggaggactttgaggccacc ccaggcgtggacaggcgctgcgagcgtgccacggattacagcaggtcctcgtcgacctcc agccaggaggagaagtcgttccgcggggaggagccggcagccggggggatccccatcgag cgggccgtgtcctctgagggagcccggcccactgcagacctcgccttccagccctcgcag cccctgagcaagtccagctcctcgccggaactgcagagcctgcaggacgtcctcggggac cccggggacaaggctgacctcggccggctgagccccgaggccaaagcccggtcacagtcc gggaccctggacggggaaagcgcctcctggtcagcctcgggggcagacagccagggcctg ggcccaccccagcccgagggcccctcgcctgccagctgcccccgctcccccagcggcctg cggccccgaggctacaccatctccgactcggccccgtcccgcaggggcaagagggtggag cgggatgccctaaagagcagagccggggccgccaacgctgagaaggtgcctggcatcaac cccagcttcgtgttcctgcagctctaccactcgcccttcttcggggatgagtccaacaag ccgatccttctgcccaacgagaccttcgagcggtccgtgcagctcctcgaccagatcccg tcctacgacacgcacaagatcgccgtcctgtacgtgggcgaaggccagagcagcagcgag ctcgccatcctgtccaacgagcacggctcctaccggtacacggagttcctgacggggctg ggccggctcatcgagctcaaggactgccagcctgacaaggtgtacctgggcggcctggac gtgtgcggcgaggacggccagttcacctactgctggcacgatgacatcatgcaagcggtc ttccacatcgccacgctgatgcccaccaaggacggggaccggcagcgctgcgacaagaag cgccacctgggcaacgacctcgtgtccatcgtctacaacgactctggcgaggacttcaag ctgggcaccatcaagggccagttcaacttcgtgcacgtgatcatcacccccctggactac gagtgcaacctggtgtcgctgcagtgcaggaaagacatggagggcctcgtggacaccagc gtggccaagatcgtgtctgaccggaacctgcccttcgtggcccgccagatggccttgcac gccaacatggcctcccaggtgcaccacagccgctccaaccccaccgacgtctatccctcc aagtggatcgcccgcctgcgccacatcaagcggctgcgccagcgggtgcgcgaggaggcc cactacgcacaccccagcctgcccttggtgcacctgccgggccacgccaaggcaccggcg caggccccagccgagcccacgcccgcccacgagaccggccagcgcaggcgcctcatctcc tctgtggacgacttcacggagttcgtgtga

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