KEGG   Talpa occidentalis (Iberian mole): 119243687
Entry
119243687         CDS       T07495                                 
Symbol
PPP3CA
Name
(RefSeq) protein phosphatase 3 catalytic subunit alpha
  KO
K04348  serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
Organism
tod  Talpa occidentalis (Iberian mole)
Pathway
tod04010  MAPK signaling pathway
tod04020  Calcium signaling pathway
tod04022  cGMP-PKG signaling pathway
tod04114  Oocyte meiosis
tod04218  Cellular senescence
tod04310  Wnt signaling pathway
tod04360  Axon guidance
tod04370  VEGF signaling pathway
tod04380  Osteoclast differentiation
tod04625  C-type lectin receptor signaling pathway
tod04650  Natural killer cell mediated cytotoxicity
tod04658  Th1 and Th2 cell differentiation
tod04659  Th17 cell differentiation
tod04660  T cell receptor signaling pathway
tod04662  B cell receptor signaling pathway
tod04720  Long-term potentiation
tod04724  Glutamatergic synapse
tod04728  Dopaminergic synapse
tod04921  Oxytocin signaling pathway
tod04922  Glucagon signaling pathway
tod04924  Renin secretion
tod05010  Alzheimer disease
tod05014  Amyotrophic lateral sclerosis
tod05020  Prion disease
tod05022  Pathways of neurodegeneration - multiple diseases
tod05031  Amphetamine addiction
tod05152  Tuberculosis
tod05163  Human cytomegalovirus infection
tod05166  Human T-cell leukemia virus 1 infection
tod05167  Kaposi sarcoma-associated herpesvirus infection
tod05170  Human immunodeficiency virus 1 infection
tod05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
tod05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:tod00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    119243687 (PPP3CA)
   04310 Wnt signaling pathway
    119243687 (PPP3CA)
   04370 VEGF signaling pathway
    119243687 (PPP3CA)
   04020 Calcium signaling pathway
    119243687 (PPP3CA)
   04022 cGMP-PKG signaling pathway
    119243687 (PPP3CA)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    119243687 (PPP3CA)
   04218 Cellular senescence
    119243687 (PPP3CA)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    119243687 (PPP3CA)
   04650 Natural killer cell mediated cytotoxicity
    119243687 (PPP3CA)
   04660 T cell receptor signaling pathway
    119243687 (PPP3CA)
   04658 Th1 and Th2 cell differentiation
    119243687 (PPP3CA)
   04659 Th17 cell differentiation
    119243687 (PPP3CA)
   04662 B cell receptor signaling pathway
    119243687 (PPP3CA)
  09152 Endocrine system
   04922 Glucagon signaling pathway
    119243687 (PPP3CA)
   04921 Oxytocin signaling pathway
    119243687 (PPP3CA)
   04924 Renin secretion
    119243687 (PPP3CA)
  09156 Nervous system
   04724 Glutamatergic synapse
    119243687 (PPP3CA)
   04728 Dopaminergic synapse
    119243687 (PPP3CA)
   04720 Long-term potentiation
    119243687 (PPP3CA)
  09158 Development and regeneration
   04360 Axon guidance
    119243687 (PPP3CA)
   04380 Osteoclast differentiation
    119243687 (PPP3CA)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    119243687 (PPP3CA)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    119243687 (PPP3CA)
   05170 Human immunodeficiency virus 1 infection
    119243687 (PPP3CA)
   05163 Human cytomegalovirus infection
    119243687 (PPP3CA)
   05167 Kaposi sarcoma-associated herpesvirus infection
    119243687 (PPP3CA)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    119243687 (PPP3CA)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    119243687 (PPP3CA)
   05014 Amyotrophic lateral sclerosis
    119243687 (PPP3CA)
   05020 Prion disease
    119243687 (PPP3CA)
   05022 Pathways of neurodegeneration - multiple diseases
    119243687 (PPP3CA)
  09165 Substance dependence
   05031 Amphetamine addiction
    119243687 (PPP3CA)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    119243687 (PPP3CA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:tod01009]
    119243687 (PPP3CA)
Enzymes [BR:tod01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     119243687 (PPP3CA)
Protein phosphatases and associated proteins [BR:tod01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Catalytic subunits
     119243687 (PPP3CA)
SSDB
Motif
Pfam: Metallophos
Other DBs
NCBI-GeneID: 119243687
NCBI-ProteinID: XP_037365530
LinkDB
Position
Unknown
AA seq 508 aa
MSEPKASDPKLSTTDRVVKAVPFPPSHRLTAKEVFDGDGKPRVDVLKAHLMKEGRLEESV
ALRIVTEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYV
DRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMD
AFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFG
NEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFP
SLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEK
VTEMLVNVLNICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESV
LTLKGLTPTGMLPSGVLSGGKQTLQSAIKGFSPQHKITSFEEAKGLDRINERMPPRRDAP
PSDASLNSINKALAAEANGTDSNGSNIQ
NT seq 1527 nt   +upstreamnt  +downstreamnt
atgtccgagcccaaggcctccgaccccaagttgtcgacgaccgacagggtggtgaaagct
gtcccgttccctcccagccaccggctcacggcgaaggaagtgttcgatggcgacgggaag
ccacgcgtggacgtgctgaaggcgcacctcatgaaggagggccggctggaggagagcgtg
gcgctgaggattgtcaccgagggggcctccatcctgcggcaggagaagaacttgctagac
atcgacgctccggtcacagtctgcggagacatccatgggcaattcttcgacctgatgaag
ctctttgaagtgggggggtcccctgccaacacgcgctacctcttcctgggggactacgtc
gacagagggtacttcagcatcgaatgtgtgctgtatctgtgggccttgaaaatcctttac
cccaaaacactgttcttacttcgcgggaatcacgagtgcagacatctaacggagtatttc
acatttaaacaagaatgtaagatcaagtactcggagcgcgtgtacgacgcctgcatggac
gccttcgactgtctgcccctggccgccctgatgaaccagcagttcctgtgcgtgcacggc
ggcctgtcccccgagatcaacaccctggacgacatccggaaattagaccggttcaaggag
ccgcccgcctacgggcccatgtgcgacatcctgtggtccgaccccctggaggacttcggc
aacgagaagactcaggagcacttcacgcacaacacggtccggggctgttcctacttctac
agttacccggccgtgtgtgagttcctacagcacaataacctgttgtctatactccgagcc
cacgaagcgcaggacgcggggtaccgcatgtacaggaagagccagaccacgggcttcccg
tcgctcatcaccattttctcagcgccgaactacttagacgtgtacaataacaaagccgcg
gtgctgaagtacgagaacaacgtcatgaacatcaggcagttcaactgctcccctcacccg
tactggctccccaacttcatggacgtcttcacctggtcgctgccgtttgtcggggagaaa
gtgaccgagatgctggtcaacgtcctcaacatctgctcggacgacgagctgggctcggag
gaggatgggtttgacggcgcgacggcggcagccaggaaggaggtgatccggaacaagatc
cgggccatcggcaagatggccagggtgttctccgtgctcagagaggagagcgagagtgtg
ctgacgctgaaaggcctgacgcccacgggcatgctccccagcggggtgctctccggaggg
aagcagacgctgcagagcgctatcaagggcttctcgccgcagcacaagatcaccagcttc
gaggaggccaagggcctggaccgcatcaacgagcgcatgccgccccgccgggacgcgccg
ccctccgacgccagcctcaactccatcaacaaggcgctggccgccgaggccaacggcacc
gacagcaacggcagcaacatccagtga

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