Talpa occidentalis (Iberian mole): 119245001
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Entry
119245001 CDS
T07495
Symbol
ATP2A2
Name
(RefSeq) sarcoplasmic/endoplasmic reticulum calcium ATPase 2 isoform X1
KO
K05853
P-type Ca2+ transporter type 2A [EC:
7.2.2.10
]
Organism
tod
Talpa occidentalis (Iberian mole)
Pathway
tod04020
Calcium signaling pathway
tod04022
cGMP-PKG signaling pathway
tod04024
cAMP signaling pathway
tod04148
Efferocytosis
tod04260
Cardiac muscle contraction
tod04261
Adrenergic signaling in cardiomyocytes
tod04380
Osteoclast differentiation
tod04919
Thyroid hormone signaling pathway
tod04972
Pancreatic secretion
tod05010
Alzheimer disease
tod05017
Spinocerebellar ataxia
tod05022
Pathways of neurodegeneration - multiple diseases
tod05410
Hypertrophic cardiomyopathy
tod05412
Arrhythmogenic right ventricular cardiomyopathy
tod05414
Dilated cardiomyopathy
tod05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
tod00001
]
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
119245001 (ATP2A2)
04024 cAMP signaling pathway
119245001 (ATP2A2)
04022 cGMP-PKG signaling pathway
119245001 (ATP2A2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
119245001 (ATP2A2)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
119245001 (ATP2A2)
09153 Circulatory system
04260 Cardiac muscle contraction
119245001 (ATP2A2)
04261 Adrenergic signaling in cardiomyocytes
119245001 (ATP2A2)
09154 Digestive system
04972 Pancreatic secretion
119245001 (ATP2A2)
09158 Development and regeneration
04380 Osteoclast differentiation
119245001 (ATP2A2)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
119245001 (ATP2A2)
05017 Spinocerebellar ataxia
119245001 (ATP2A2)
05022 Pathways of neurodegeneration - multiple diseases
119245001 (ATP2A2)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
119245001 (ATP2A2)
05412 Arrhythmogenic right ventricular cardiomyopathy
119245001 (ATP2A2)
05414 Dilated cardiomyopathy
119245001 (ATP2A2)
05415 Diabetic cardiomyopathy
119245001 (ATP2A2)
Enzymes [BR:
tod01000
]
7. Translocases
7.2 Catalysing the translocation of inorganic cations
7.2.2 Linked to the hydrolysis of a nucleoside triphosphate
7.2.2.10 P-type Ca2+ transporter
119245001 (ATP2A2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Cation_ATPase
Cation_ATPase_C
E1-E2_ATPase
Cation_ATPase_N
Hydrolase
Hydrolase_3
HAD
Motif
Other DBs
NCBI-GeneID:
119245001
NCBI-ProteinID:
XP_037367088
LinkDB
All DBs
Position
Unknown
AA seq
1042 aa
AA seq
DB search
MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGANELPAEEGKTLLELVIEQFEDL
LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK
EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL
TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV
ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCRMFILDKVDGDTCSLNEFTITGSTYAPIGEVHKDDKPVKCHQYDGLVELATICALC
NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK
KEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTPGI
KQKIMSVIREWGSGSDTLRCLALATHDSPLKREEMNLEDSANFIKYETNLTFVGCVGMLD
PPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDDL
NPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMG
SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL
GFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISRWLFFRYLAIG
CYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMAL
SVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITP
LNLTQWLMVLKISLPVILMDETLKFVARKYLEPGKECVQPATKSCSFSACTDGISWPFVL
LIMPLVVWVYSTDTNFSDMFWS
NT seq
3129 nt
NT seq
+upstream
nt +downstream
nt
atggagaacgcgcacaccaagacggtggaggaggtgctgggccacttcggcgtcaacgag
agcaccgggctgagcctggagcaggtcaagaagctcaaggagcgctggggcgccaacgag
ttaccggctgaagaaggaaaaaccttactggaacttgtgattgagcagtttgaagactta
ctagttagaattttattattggcagcgtgtatatcttttgttttggcttggtttgaagaa
ggtgaagagacaattactgcctttgtagaaccctttgtaattttacttatattagtagcc
aatgcaattgtgggtgtatggcaggaaagaaatgctgaaaatgccattgaagctcttaag
gagtatgagcctgaaatgggcaaagtgtatcgacaggacagaaagagtgtacagcgaatt
aaggctaaagacatagttcctggggatattgtagaaattgctgttggtgacaaagttcct
gctgatataagattaacttccatcaaatccactactctaagagttgaccagtccattctc
acaggtgaatctgtctctgtcattaagcacactgaccctgtccctgacccacgtgccgtc
aaccaagataagaagaacatgctcttttccggcaccaacattgctgctggaaaagctatg
ggagtggtggtggcaacgggagttaacactgaaattggcaagatccgggatgaaatggtg
gcgacagaacaggagagaacacccctccagcagaaactggatgagtttggggaacagctt
tccaaagtcatctcccttatttgcattgccgtctggatcataaacatcgggcatttcaat
gaccctgtccacggaggctcctggatcaggggcgccatttactactttaagattgcagtg
gccctggctgtagctgccattcctgaaggcctgcctgctgtcatcaccacctgcttggct
ctcggaactcgcagaatggcaaagaaaaatgccattgttcgaagcctgccgtccgtggaa
acccttggttgcacttctgttatctgctcagacaagacgggtacgctgacaacgaaccag
atgtcagtctgcaggatgttcattctggacaaagttgatggtgacacttgttcccttaat
gagttcaccataactggatcaacatacgcaccgattggagaagtgcataaagatgataaa
ccagtgaaatgccatcagtatgatggtcttgtagaattggcaacaatttgtgctctttgt
aatgactctgctttggattacaatgaggctaaaggtgtgtatgaaaaagtcggagaagct
acagagactgctctcacttgcctggtagagaagatgaatgtatttgataccgaattgaag
ggtctttctaaaatagaacgagcaaatgcctgcaactcggtgattaaacaattgatgaaa
aaagaatttactctggagttctcacgtgatagaaaatcaatgtcggtttactgtacacca
aacaagcccagccgcacatccatgagcaagatgttcgtgaagggcgctcctgaaggtgtt
attgacaggtgtacccacattcgagttggaagtactaaagtccccatgacccctggaatc
aaacagaagatcatgtctgtcattcgggaatggggtagtggcagcgacacgctgcggtgc
ctggccctggccactcacgacagcccgctgaaaagagaagaaatgaaccttgaggactct
gccaacttcattaaatacgagaccaacctgaccttcgtgggctgtgtgggcatgctggac
cctccaaggattgaagtggcctcctctgtgaagctgtgccgtcaagcaggcatccgggtc
atcatgattacgggggacaacaagggcactgcggtggccatctgtcgccgcattggcatc
ttcgggcaggatgaggatgtgacgtcaaaggcttttacaggtcgggagttcgacgacctc
aatccttctgcgcaaagagatgcctgcttgaatgcccgctgcttcgctcgggttgaaccc
tcccacaagtctaaaattgtagaatttcttcagtcttttgatgagattacagctatgaca
ggggacggtgtgaatgatgctcccgccctgaagaaggccgagattggcattgccatgggc
tctggcactgcggtggctaaaactgcctctgagatggtcctggcggacgacaacttctcc
accatcgtggccgctgtggaggaggggcgggccatctacaacaacatgaagcagttcatc
cgctacctcatctcctccaacgtgggggaagttgtctgcattttcctgacagcagccctt
ggatttcctgaggctttaattcctgtgcagctgctctgggtcaacctggtgacagacggc
ttgcctgccaccgcgctgggcttcaacccgcccgatctcgacatcatgaataagccgccc
cggaacccaaaggagccgctgattagcaggtggctcttcttccgttacctggccatcggc
tgttacgttggcgctgctaccgtgggtgctgctgcgtggtggttcattgctgccgacggt
ggtccccgagtgtccttctaccagctgagtcatttcctgcagtgtaaggaggacaatcca
gactttgaaggagtggattgtgcaatctttgaatccccgtatccgatgacaatggcgctc
tctgttctagtaaccatagagatgtgcaacgccctcaacagcttgtctgaaaaccagtcc
ctgctaaggatgcctccttgggagaacatctggctggtgggctccatctgcctgtccatg
tctctccacttcctcatcctctatgtggaacccctgccgcttatcttccagatcacaccg
ctgaatttgacccagtggctgatggtgctcaaaatttccttgcctgtgatcctaatggac
gagacactcaagtttgtggcccgcaagtacctggagcctggtaaagagtgtgtgcagcct
gccaccaaatcctgctcgttctcggcatgcaccgatgggatttcctggccgttcgtgctg
ctcataatgcccctggtggtctgggtgtatagcacagacactaactttagtgatatgttc
tggtcttga
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