Talpa occidentalis (Iberian mole): 119245137
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Entry
119245137 CDS
T07495
Symbol
IGF1R
Name
(RefSeq) insulin-like growth factor 1 receptor isoform X1
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
tod
Talpa occidentalis (Iberian mole)
Pathway
tod01521
EGFR tyrosine kinase inhibitor resistance
tod01522
Endocrine resistance
tod04010
MAPK signaling pathway
tod04014
Ras signaling pathway
tod04015
Rap1 signaling pathway
tod04066
HIF-1 signaling pathway
tod04068
FoxO signaling pathway
tod04081
Hormone signaling
tod04114
Oocyte meiosis
tod04140
Autophagy - animal
tod04144
Endocytosis
tod04150
mTOR signaling pathway
tod04151
PI3K-Akt signaling pathway
tod04152
AMPK signaling pathway
tod04211
Longevity regulating pathway
tod04213
Longevity regulating pathway - multiple species
tod04510
Focal adhesion
tod04520
Adherens junction
tod04550
Signaling pathways regulating pluripotency of stem cells
tod04730
Long-term depression
tod04913
Ovarian steroidogenesis
tod04914
Progesterone-mediated oocyte maturation
tod05200
Pathways in cancer
tod05202
Transcriptional misregulation in cancer
tod05205
Proteoglycans in cancer
tod05214
Glioma
tod05215
Prostate cancer
tod05218
Melanoma
tod05224
Breast cancer
tod05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
tod00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
119245137 (IGF1R)
04014 Ras signaling pathway
119245137 (IGF1R)
04015 Rap1 signaling pathway
119245137 (IGF1R)
04066 HIF-1 signaling pathway
119245137 (IGF1R)
04068 FoxO signaling pathway
119245137 (IGF1R)
04151 PI3K-Akt signaling pathway
119245137 (IGF1R)
04152 AMPK signaling pathway
119245137 (IGF1R)
04150 mTOR signaling pathway
119245137 (IGF1R)
09133 Signaling molecules and interaction
04081 Hormone signaling
119245137 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
119245137 (IGF1R)
04140 Autophagy - animal
119245137 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
119245137 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
119245137 (IGF1R)
04520 Adherens junction
119245137 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
119245137 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
119245137 (IGF1R)
04914 Progesterone-mediated oocyte maturation
119245137 (IGF1R)
09156 Nervous system
04730 Long-term depression
119245137 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
119245137 (IGF1R)
04213 Longevity regulating pathway - multiple species
119245137 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
119245137 (IGF1R)
05202 Transcriptional misregulation in cancer
119245137 (IGF1R)
05205 Proteoglycans in cancer
119245137 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
119245137 (IGF1R)
05214 Glioma
119245137 (IGF1R)
05218 Melanoma
119245137 (IGF1R)
05215 Prostate cancer
119245137 (IGF1R)
05224 Breast cancer
119245137 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
119245137 (IGF1R)
01522 Endocrine resistance
119245137 (IGF1R)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
tod01001
]
119245137 (IGF1R)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
tod04090
]
119245137 (IGF1R)
Enzymes [BR:
tod01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
119245137 (IGF1R)
Protein kinases [BR:
tod01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
119245137 (IGF1R)
CD molecules [BR:
tod04090
]
Proteins
119245137 (IGF1R)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Pkinase
Furin-like
fn3
Ig_DSCAM-DSCAML_C
Kinase-like
Insulin_TMD
Motif
Other DBs
NCBI-GeneID:
119245137
NCBI-ProteinID:
XP_054550733
LinkDB
All DBs
Position
Unknown
AA seq
1368 aa
AA seq
DB search
MKSGSGGGSPTSLWGLLFLSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLH
ILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIF
EMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPQKECGD
LCPGTMEEKPMCEKTTINNEYNYRCWTTNRCQKMCPSACGKRACTENNECCHPECLGSCS
APDNDTACVACRHYYYAGVCVPSCPPSTYRFEGWRCVDRDFCANIPSAEGSDSEGFVIHD
GECMQECPSGFIRNGTQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTILKGNL
LINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRQILGEEQLEGNYSF
YVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTR
NNGERASCESDVLHFTSTNTWKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDG
QDACGSNSWNMVDVDLPPNKDIDPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSE
ILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDSYLYQH
NYCSKADKIPIRKYADGTIDVEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYR
KVFENFLHNSIFVPRPERKRRDVMQVANTTMSSRSRNTTAADTYNVTDPEELETEYPFFE
SRVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVT
WEPKPENSIFLKWPEPENPNGLILMYEIKYGSQIEDQRECVSRQEYRKYGGARLNRLNPG
NYTARIQATSLSGNGSWTDPVFFYVPAKPTYENFIHLIIALPVAALLIVGGLVIMLYVFH
RKRNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAK
GVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIM
ELMTRGDLKSYLRSLRPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAAR
NCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFG
VVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSF
LEIISSIKDEMEPGFREVSFYYSEENKPPEPEELDLEPENMESVPLDPSASSSSLPLPDR
HSGHKAENGPGPGVLVLRASFDERQPYAHMNGGRKNERALPLPQSSTC
NT seq
4107 nt
NT seq
+upstream
nt +downstream
nt
atgaagtctggctccggaggagggtccccgacctcgctgtgggggctcctgtttctctcc
gccgcgctctcgctctggccgacgagtggagaaatctgcggtccaggcatcgacatccgg
aacgactaccagcagctgaagcgcctggagaactgcacggtgatcgagggctacctgcac
atcctgctcatctccaaggcggaggactaccgcagctaccgcttccccaagctcaccgtc
atcaccgagtacttgctgctcttccgcgtggctggcctcgagagcctgggcgacctcttc
cccaacctcacggtcatccgcggctggaagctcttctacaactacgccctggtcatcttc
gagatgaccaatctcaaggatattgggctttacaacctgaggaacataactcggggggcc
atcaggattgagaaaaatgctgacctctgttacctctccacggtggactggtccctgatc
ctggacgcagtttccaacaactacatcgtggggaacaagccccagaaggaatgtggggac
ctgtgcccggggacgatggaggagaagccgatgtgtgagaagaccaccatcaacaacgag
tacaactaccgctgctggaccacaaaccgctgccagaaaatgtgcccgagcgcgtgcggg
aagcgggcatgcaccgagaacaatgagtgctgccaccccgagtgcctgggcagctgcagc
gcacccgacaatgacacggcctgtgtggcctgccgccactactactacgccggcgtctgc
gtccccagctgcccgcccagcacctaccgcttcgagggctggcgctgcgtggaccgcgac
ttctgtgccaacatccccagcgccgagggcagcgactcggagggcttcgtgatccacgac
ggcgagtgcatgcaggagtgcccctcggggttcatccgcaacggcacgcagagcatgtac
tgcatcccttgcgaaggtccttgccccaaagtctgtgaagaagaaaagaaaacaaagacc
atcgattcggtgacttccgcgcagatgctgcaagggtgcaccatcttgaagggcaacttg
ctcattaatatccgacgaggcaataacattgcctcggagctggagaacttcatgggactc
atcgaggtggtgacaggctatgtgaagatacggcactcccacgccttggtctctttgtcc
ttcctcaaaaacctccggcagatcttaggagaggagcagctggaggggaattactccttc
tacgtcctggacaaccagaatctgcaacagctgtgggactgggaccaccgcaacctgacc
atcaaagccgggaagatgtattttgctttcaatcccaagctgtgcgtatccgaaatttac
cgcatggaggaagtgacggggacgaaagggcgtcagagtaaaggggacatcaacaccagg
aacaacggagagagagcctcctgtgagagcgacgtcctgcacttcacctccaccaacaca
tggaagaaccgcatcatcatcacctggcaccggtaccggcccccggactacagggacctc
atcagcttcaccgtctactacaaggaagcgccctttaaaaacgttacagaatatgatggg
caagatgcctgcggctccaacagctggaacatggtggacgtggacctccctcccaacaag
gacatcgatcccggcatcctgctgcacgggctgaagccctggacgcagtacgctgtttac
gtcaaggccgtgactctgaccatggtggagaatgaccacatccgtggggccaagagtgaa
atcctctacattcgcaccaatgcttcagtgccttccatccccctggatgttctttcggca
tcaaactcctcttctcagctaatcgtgaagtggaacccaccctccctgcccaacggcaac
ctgagttactacattgtgaggtggcagcggcagccgcaggacagctacctctatcagcac
aactactgctccaaagcagacaaaatccccatcaggaaatacgctgacggcaccatagat
gtggaggaagtgacagagaaccccaagactgaagtgtgtggtggagagaaagggccttgc
tgtgcgtgccccaagactgaagccgagaagcaggcagagaaggaagaggcagaataccgc
aaggtcttcgagaacttcctgcacaactccatctttgtgcccagacctgaaaggaagcgg
agagatgtcatgcaagtcgccaacaccaccatgtccagccgaagccggaacaccacggcg
gcggacacctacaacgtcacagacccggaggagcttgagactgaataccctttctttgag
agcagagtggataacaaggagagaactgtaatttctaacctgcgaccttttactctgtac
cgcattgacatccacagctgtaaccacgaggctgagaagctgggctgcagtgcctccaac
tttgtctttgcaagaaccatgcctgcagagggagcagatgacattccaggaccagtgacc
tgggagccgaagcctgaaaactccatctttttaaagtggccagaacctgagaatcccaat
gggttgattctaatgtatgaaataaaatatggatctcaaatcgaggatcagcgggagtgt
gtgtcccggcaggagtacaggaagtatggaggggccaggctgaaccgcctcaacccgggg
aactacacggcccggatccaggctacctccctctctgggaatgggtcatggacagatcct
gtgttcttctacgtccctgccaaaccaacctatgaaaatttcatccacctgatcatcgcc
ctgcctgtggctgccctgctgatcgtgggagggctggtgataatgttgtacgtcttccac
agaaaaagaaataacagccggctggggaatggagtgctgtatgcctctgtgaacccagag
tacttcagcgcggctgacgtgtacgtgcccgatgagtgggaggtggctcgtgagaagatc
acgatgagccgagagctgggccagggctcctttgggatggtctatgaaggagtggccaag
ggtgtggttaaagacgagccggaaaccagggtggccatcaaaacagtgaacgaagccgcg
agcatgcgcgagaggatcgagtttctcaacgaggcttcggtgatgaaggagttcaactgc
caccacgtggtgcggctgctgggtgtggtgtcccagggccagccaacgctggtcatcatg
gaactgatgacgcggggggatctcaaaagctatctccggtctctgaggccagaaatggag
aataatccagtgctcgcacccccaagcctgagcaagatgatccagatggccggagagatc
gcagatggcatggcgtacctcaacgccaacaagttcgtccacagggacctcgctgcccgg
aactgcatggtggccgaagatttcacagtcaaaatcggagacttcggtatgacgagagac
atctatgagacagactattaccggaaaggagggaaaggattactgcccgtgcgctggatg
tctcctgagtccctcaaggatggagtcttcaccactcattctgatgtctggtcctttggg
gtcgtcctctgggagatcgccacactggccgagcagccgtaccagggcttgtccaacgag
caggtccttcgtttcgtcatggagggcggccttctggacaagccggacaactgccccgac
atgctgtttgaactgatgcgcatgtgctggcagtacaaccccaagatgaggccttccttc
ctggagatcattagcagcatcaaagatgagatggagccgggcttccgggaggtctccttc
tactacagcgaggagaacaagccgcccgagcccgaggagctggacctggagccggagaac
atggagagcgtccccctggacccctccgcctcctcttcctcgctgccgctgcctgacaga
cactcaggacacaaggccgagaacggcccgggccctggcgtgctggtcctgcgagccagc
ttcgacgagaggcagccttacgcccacatgaacgggggccgcaagaacgagagggccctg
cctctgccccagtcttcgacctgctga
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integrated database retrieval system
