Talpa occidentalis (Iberian mole): 119245963
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Entry
119245963 CDS
T07495
Symbol
MET
Name
(RefSeq) hepatocyte growth factor receptor
KO
K05099
proto-oncogene tyrosine-protein kinase Met [EC:
2.7.10.1
]
Organism
tod
Talpa occidentalis (Iberian mole)
Pathway
tod01521
EGFR tyrosine kinase inhibitor resistance
tod04010
MAPK signaling pathway
tod04014
Ras signaling pathway
tod04015
Rap1 signaling pathway
tod04020
Calcium signaling pathway
tod04151
PI3K-Akt signaling pathway
tod04360
Axon guidance
tod04510
Focal adhesion
tod04520
Adherens junction
tod05100
Bacterial invasion of epithelial cells
tod05144
Malaria
tod05200
Pathways in cancer
tod05202
Transcriptional misregulation in cancer
tod05205
Proteoglycans in cancer
tod05206
MicroRNAs in cancer
tod05208
Chemical carcinogenesis - reactive oxygen species
tod05211
Renal cell carcinoma
tod05218
Melanoma
tod05223
Non-small cell lung cancer
tod05225
Hepatocellular carcinoma
tod05226
Gastric cancer
tod05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
tod00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
119245963 (MET)
04014 Ras signaling pathway
119245963 (MET)
04015 Rap1 signaling pathway
119245963 (MET)
04020 Calcium signaling pathway
119245963 (MET)
04151 PI3K-Akt signaling pathway
119245963 (MET)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
119245963 (MET)
04520 Adherens junction
119245963 (MET)
09150 Organismal Systems
09158 Development and regeneration
04360 Axon guidance
119245963 (MET)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
119245963 (MET)
05202 Transcriptional misregulation in cancer
119245963 (MET)
05206 MicroRNAs in cancer
119245963 (MET)
05205 Proteoglycans in cancer
119245963 (MET)
05208 Chemical carcinogenesis - reactive oxygen species
119245963 (MET)
05230 Central carbon metabolism in cancer
119245963 (MET)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
119245963 (MET)
05226 Gastric cancer
119245963 (MET)
05218 Melanoma
119245963 (MET)
05211 Renal cell carcinoma
119245963 (MET)
05223 Non-small cell lung cancer
119245963 (MET)
09171 Infectious disease: bacterial
05100 Bacterial invasion of epithelial cells
119245963 (MET)
09174 Infectious disease: parasitic
05144 Malaria
119245963 (MET)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
119245963 (MET)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
tod01001
]
119245963 (MET)
Enzymes [BR:
tod01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
119245963 (MET)
Protein kinases [BR:
tod01001
]
Receptor tyrosine kinases (RTK)
MET family
119245963 (MET)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
TIG
Pkinase
Sema
PSI
Pkinase_fungal
Kinase-like
Linker_histone
PepSY_TM
Motif
Other DBs
NCBI-GeneID:
119245963
NCBI-ProteinID:
XP_037367965
LinkDB
All DBs
Position
Unknown
AA seq
1380 aa
AA seq
DB search
MKTPAVLAPVILVLLFTLVQKSNGECKEALVKSEMNVNMKYQLPNFTAQTPIQNVVLHKH
HIYVGAINYIYVLNDNNLQKVAEYKTGPVLEHPDCIPCQNCSHKTNSSGGIWKDNINMAL
LIDTYYDDQLISCGSVHRGTCQRHVLPPGNTADIQSEVHCMYSPQADEDPSQCPDCVVSA
LGTKVLLSEKDRFINFFVGNTINSSYLPDHSLHSISVRRLKETQDGFKFLTDQSYIDVLP
EFRDSYPIKYIHAFESNHFIYFLTVQRETLDAQTFHTRIIRFCSVDSGLHSYMEMPLECI
LTEKRRKRATREEMFNILQAAYVSKPGAHLAKQIGANLNDDILYGVFAQSKPDSAEPMNR
SAVCAFPIKYINEFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEARSDEYRTE
FTTALQRVDLFMGQFNQILLTSISTFIKGDLTIANLGTSEGRFIQVVVSRSRSTPHVNFH
LDSHPVSPEVIVEHPLNQNGYTLVVTGKKITRIPLNGLGCEHFQSCSQCLSAPPFVQCGW
CHNKCVQLEECPSGTWTQETCLPIIYKVFPTSAPLEGGTTLTICGWDFGLRKNNKFDLKK
TRILLGNESCTLTLSESTANTLKCTVGPAMNEHFNMSISISNSRGTAQYSTFSYVDPKIT
SISPNYGPKTGGTLLTITGKFLNSGNSRHISIGGKTCTLKSVSDNVLECYTPAQTTSTEF
PVKLKIDLANRETNSFSYREDPFVYEIHPTKSFISGGSTITGVGKNLNSVSVLRMVISVP
ETERNFTVACQHRSNSEIICCTTPSLQQLNLQLPLTTKAFFMLDGMHSKYFDLIYVHNPV
FKPFEKPVKISIGNENVLEIKGNDIDPEAVKGEVLKVGNKSCERIQSYSETVLCTVPNDL
LKLNSELNIEWKQAVSSTVLGKVIVQPDQNVTGLIVGFVSISIILLLLFGLFLWWKKRKQ
IKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESVDYRATFPEDQFPNSTQNGS
CRQVQYPLTDLSPILNSGDSDISSPLLQNTVHIDLSALNPELVQAVQHVVIGPSNLIVHF
NEVIGRGHFGCVYHGTLLDSDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVL
SLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKF
VHRDLAARNCMLDESFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKF
TTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCW
HPKAELRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKCVAPYPSLLSQDNIDGERGT
NT seq
4143 nt
NT seq
+upstream
nt +downstream
nt
atgaaaacccctgctgtgcttgcacctgtcatccttgtgcttctgtttaccttggtacag
aagagcaatggggagtgcaaagaagcactggtaaagtccgagatgaatgtgaacatgaag
tatcagcttcccaacttcactgcgcaaacacccatccagaatgttgttttacacaagcac
cacatttacgtcggtgctattaactacatatatgttttaaatgacaacaatcttcagaaa
gttgctgagtacaagactgggcctgtgctagaacacccagattgtattccttgtcagaac
tgcagccacaaaaccaattcatcaggtggcatttggaaagataatatcaacatggctctg
cttattgacacatactatgatgaccagctcattagctgcggcagtgttcacagagggacc
tgccagcgacacgtgcttccacctggcaacactgctgacatacagtcggaggttcactgc
atgtactctccacaggcagatgaagatccgagccagtgtcctgactgtgtggtgagcgcc
ctgggaaccaaagtcctcctgtctgaaaaggacaggttcatcaacttcttcgtgggcaat
actataaattcttcctaccttccagatcattcattgcattcaatatcagtgagaagacta
aaggaaacacaagatggttttaagtttttaacagatcagtcgtatatcgatgttctacct
gagttccgagattcttaccccattaagtacatccacgcctttgaaagcaaccattttatt
tactttttgacagtccagcgggaaactctagacgctcagacttttcacacaagaataatc
agattctgttctgtagactctgggctgcattcctacatggaaatgccactggagtgtatt
ctcacagaaaagagaagaaagagagccacaagggaagaaatgtttaatattctccaagct
gcgtacgtcagtaagcctggtgcccatcttgctaaacaaataggagccaacctgaatgat
gacattctctacggggtgtttgcacaaagcaagccagattctgctgaaccaatgaatcgc
tcggctgtctgtgctttccccatcaaatacattaatgagttcttcaacaagattgtcaac
aaaaacaatgtaaggtgtctccagcatttttatggaccgaaccatgaacactgctttaat
aggacacttttgagaaattcatcaggctgtgaagcgcgcagtgatgaataccgaacggag
tttaccacagctttgcaacgtgttgacttattcatgggccaattcaaccaaatcctccta
acatctatttccaccttcattaaaggagacctcaccatcgctaatcttgggacatcagag
ggtcgcttcattcaggttgtagtttctcgatcaagatcaaccccccatgtgaattttcac
ctggattcccaccctgtgtctccagaagtgattgtggaacatccgctaaaccaaaatggc
tacacactggttgtcactgggaaaaagatcaccaggatcccactgaatggcttgggctgt
gaacatttccagtcctgcagtcagtgtctctccgccccaccctttgttcagtgtggctgg
tgccacaataaatgtgtacagttggaggaatgccccagcggaacatggactcaggagacc
tgtctgcctataatctataaggttttcccaactagtgcacctcttgaaggaggaacaaca
ttgaccatatgtggctgggactttggactcaggaagaataataaatttgatttaaagaaa
accaggattctccttggaaatgagagctgcaccttgaccctaagtgagagcactgcaaat
acgcttaaatgcactgttggtcctgcaatgaatgaacatttcaatatgtccataagtatt
tcaaacagtagagggacagcacaatatagtacattttcctatgtggatcctaaaataaca
agtatttctccaaattatggtcctaagactggtggcactttacttactataactggaaag
ttcctaaacagtggaaattctagacacatttcaattggtggaaagacatgcactttgaaa
agtgtgtcagataacgttctcgagtgttatacgccagcccaaaccacttcaactgagttt
cctgttaaattgaaaattgacttagccaaccgagagaccaacagcttcagttaccgggaa
gacccctttgtctatgaaattcatccaaccaaatcttttattagtggtgggagcacaata
acaggtgttggaaaaaacctgaattcagttagtgtcctgaggatggtgataagtgtgcct
gaaacagaaaggaactttacagtggcatgtcaacatcgctctaattcagaaataatctgc
tgtacaactccttcactgcaacagctgaatctgcaactccccctgacaaccaaagccttt
ttcatgttagatgggatgcattccaaatactttgatctcatttatgtacataatcctgta
tttaagccttttgaaaagccagtgaagatctcaataggcaatgaaaatgtactggaaatt
aagggaaatgatattgaccctgaagcagttaaaggtgaagtgttaaaagttggaaataag
agctgtgagagaatacagtcatactctgaaaccgttttatgtacagtccccaatgacctc
ctgaaattgaacagtgagctaaatatagagtggaaacaagcggtttcttcaactgtcctt
ggaaaagtaatagttcaaccagatcagaatgtcacaggactgattgttggttttgtttca
atatcaataatactgttattattatttgggcttttcctgtggtggaaaaagagaaagcaa
attaaagatctaggcagtgaattagttcgttatgatgcaagagtacacactcctcacttg
gataggcttgtaagtgcccgaagtgtaagcccaactacagaaatggtatcaaatgaatct
gtggactacagagctacctttccagaagaccagtttcctaactcaactcagaatggatct
tgcagacaagtgcagtatcctctgacagacctatcccccatcctaaatagtggggactct
gatatatctagtccattactgcaaaatactgtccacattgacctcagtgctttaaatcca
gagctggttcaggcagtccagcacgtagtaattgggccaagcaacctgattgtacatttc
aatgaagtcataggaagaggacattttgggtgtgtatatcatgggactttgctggacagt
gatgacaagaagattcactgtgctgtgaaatccttgaataggatcactgacataggagaa
gtttctcagtttctgacggagggaatcatcatgaaagattttagtcaccccaatgttctc
tcactcctgggaatctgccttcggagtgaggggtctccattagtggtcctaccatacatg
aaacatggagatcttcgaaatttcattagaaatgagactcataatccaactgtaaaagac
cttattggttttggtcttcaagtagccaaagggatgaaatatcttgcaagcaaaaagttt
gtccacagagacttggctgcaagaaactgcatgctggatgaaagtttcactgtcaaggtt
gctgattttggtcttgccagagacatgtatgataaagaatactatagtgttcacaacaaa
actggtgcaaaactgccagtgaagtggatggctctagaaagtctacaaactcagaagttc
accaccaagtcagatgtgtggtcctttggcgtgcttctctgggaactaatgaccagagga
gcaccaccttatcctgacgtcaacacctttgatataacagtttacttgttgcaaggcaga
aggctcttacaacccgaatactgcccagatcccttatacgaagtgatgctaaaatgctgg
caccctaaagctgaactgcgcccatccttctctgaactggtctccaggatatcagcaata
ttctctactttcatcggggagcactatgtccatgtgaatgctacttatgtgaatgtcaaa
tgtgtggctccatatccttctctcttatcacaagataacattgatggcgagaggggcaca
tga
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