Talpa occidentalis (Iberian mole): 119247132
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Entry
119247132 CDS
T07495
Symbol
MAPK12
Name
(RefSeq) mitogen-activated protein kinase 12
KO
K04441
p38 MAP kinase [EC:
2.7.11.24
]
Organism
tod
Talpa occidentalis (Iberian mole)
Pathway
tod01522
Endocrine resistance
tod04010
MAPK signaling pathway
tod04015
Rap1 signaling pathway
tod04068
FoxO signaling pathway
tod04071
Sphingolipid signaling pathway
tod04114
Oocyte meiosis
tod04148
Efferocytosis
tod04218
Cellular senescence
tod04261
Adrenergic signaling in cardiomyocytes
tod04370
VEGF signaling pathway
tod04380
Osteoclast differentiation
tod04550
Signaling pathways regulating pluripotency of stem cells
tod04611
Platelet activation
tod04613
Neutrophil extracellular trap formation
tod04620
Toll-like receptor signaling pathway
tod04621
NOD-like receptor signaling pathway
tod04622
RIG-I-like receptor signaling pathway
tod04625
C-type lectin receptor signaling pathway
tod04657
IL-17 signaling pathway
tod04658
Th1 and Th2 cell differentiation
tod04659
Th17 cell differentiation
tod04660
T cell receptor signaling pathway
tod04664
Fc epsilon RI signaling pathway
tod04668
TNF signaling pathway
tod04670
Leukocyte transendothelial migration
tod04714
Thermogenesis
tod04722
Neurotrophin signaling pathway
tod04723
Retrograde endocannabinoid signaling
tod04728
Dopaminergic synapse
tod04750
Inflammatory mediator regulation of TRP channels
tod04912
GnRH signaling pathway
tod04914
Progesterone-mediated oocyte maturation
tod04917
Prolactin signaling pathway
tod04926
Relaxin signaling pathway
tod04932
Non-alcoholic fatty liver disease
tod04933
AGE-RAGE signaling pathway in diabetic complications
tod04935
Growth hormone synthesis, secretion and action
tod04936
Alcoholic liver disease
tod05014
Amyotrophic lateral sclerosis
tod05020
Prion disease
tod05022
Pathways of neurodegeneration - multiple diseases
tod05132
Salmonella infection
tod05133
Pertussis
tod05135
Yersinia infection
tod05140
Leishmaniasis
tod05142
Chagas disease
tod05145
Toxoplasmosis
tod05152
Tuberculosis
tod05161
Hepatitis B
tod05163
Human cytomegalovirus infection
tod05167
Kaposi sarcoma-associated herpesvirus infection
tod05169
Epstein-Barr virus infection
tod05170
Human immunodeficiency virus 1 infection
tod05171
Coronavirus disease - COVID-19
tod05205
Proteoglycans in cancer
tod05208
Chemical carcinogenesis - reactive oxygen species
tod05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
tod05415
Diabetic cardiomyopathy
tod05417
Lipid and atherosclerosis
tod05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
tod00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
119247132 (MAPK12)
04015 Rap1 signaling pathway
119247132 (MAPK12)
04370 VEGF signaling pathway
119247132 (MAPK12)
04668 TNF signaling pathway
119247132 (MAPK12)
04068 FoxO signaling pathway
119247132 (MAPK12)
04071 Sphingolipid signaling pathway
119247132 (MAPK12)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
119247132 (MAPK12)
09143 Cell growth and death
04114 Oocyte meiosis
119247132 (MAPK12)
04218 Cellular senescence
119247132 (MAPK12)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
119247132 (MAPK12)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
119247132 (MAPK12)
04613 Neutrophil extracellular trap formation
119247132 (MAPK12)
04620 Toll-like receptor signaling pathway
119247132 (MAPK12)
04621 NOD-like receptor signaling pathway
119247132 (MAPK12)
04622 RIG-I-like receptor signaling pathway
119247132 (MAPK12)
04625 C-type lectin receptor signaling pathway
119247132 (MAPK12)
04660 T cell receptor signaling pathway
119247132 (MAPK12)
04658 Th1 and Th2 cell differentiation
119247132 (MAPK12)
04659 Th17 cell differentiation
119247132 (MAPK12)
04657 IL-17 signaling pathway
119247132 (MAPK12)
04664 Fc epsilon RI signaling pathway
119247132 (MAPK12)
04670 Leukocyte transendothelial migration
119247132 (MAPK12)
09152 Endocrine system
04912 GnRH signaling pathway
119247132 (MAPK12)
04914 Progesterone-mediated oocyte maturation
119247132 (MAPK12)
04917 Prolactin signaling pathway
119247132 (MAPK12)
04926 Relaxin signaling pathway
119247132 (MAPK12)
04935 Growth hormone synthesis, secretion and action
119247132 (MAPK12)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
119247132 (MAPK12)
09156 Nervous system
04728 Dopaminergic synapse
119247132 (MAPK12)
04723 Retrograde endocannabinoid signaling
119247132 (MAPK12)
04722 Neurotrophin signaling pathway
119247132 (MAPK12)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
119247132 (MAPK12)
09158 Development and regeneration
04380 Osteoclast differentiation
119247132 (MAPK12)
09159 Environmental adaptation
04714 Thermogenesis
119247132 (MAPK12)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
119247132 (MAPK12)
05208 Chemical carcinogenesis - reactive oxygen species
119247132 (MAPK12)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
119247132 (MAPK12)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
119247132 (MAPK12)
05161 Hepatitis B
119247132 (MAPK12)
05171 Coronavirus disease - COVID-19
119247132 (MAPK12)
05163 Human cytomegalovirus infection
119247132 (MAPK12)
05167 Kaposi sarcoma-associated herpesvirus infection
119247132 (MAPK12)
05169 Epstein-Barr virus infection
119247132 (MAPK12)
09171 Infectious disease: bacterial
05132 Salmonella infection
119247132 (MAPK12)
05135 Yersinia infection
119247132 (MAPK12)
05133 Pertussis
119247132 (MAPK12)
05152 Tuberculosis
119247132 (MAPK12)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
119247132 (MAPK12)
05140 Leishmaniasis
119247132 (MAPK12)
05142 Chagas disease
119247132 (MAPK12)
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
119247132 (MAPK12)
05020 Prion disease
119247132 (MAPK12)
05022 Pathways of neurodegeneration - multiple diseases
119247132 (MAPK12)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
119247132 (MAPK12)
05418 Fluid shear stress and atherosclerosis
119247132 (MAPK12)
05415 Diabetic cardiomyopathy
119247132 (MAPK12)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
119247132 (MAPK12)
04932 Non-alcoholic fatty liver disease
119247132 (MAPK12)
04933 AGE-RAGE signaling pathway in diabetic complications
119247132 (MAPK12)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
119247132 (MAPK12)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
tod01001
]
119247132 (MAPK12)
Enzymes [BR:
tod01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.24 mitogen-activated protein kinase
119247132 (MAPK12)
Protein kinases [BR:
tod01001
]
Serine/threonine kinases: CMGC group
MAPK family [OT]
119247132 (MAPK12)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
ABC1
APH
Kdo
Haspin_kinase
Pribosyltran_N
Kinase-like
DUF4287
Motif
Other DBs
NCBI-GeneID:
119247132
NCBI-ProteinID:
XP_037369247
LinkDB
All DBs
Position
Unknown
AA seq
367 aa
AA seq
DB search
MSSPPPARRGFYRQEVTSTAWEVRAEYRDLQPVGSGAYGAVCSAVDSRSGAKVAIKKLYR
PFQSALFAKRAYRELRLLKHMRHENVIGLLDVFTPDESLDDFTDFYLVMPFMGTDLGKLM
KHEQLSEDRVQFLVFQMLKGLKYIHAAGVIHRDLKPGNLAVNEDCELKILDFGLARQADS
EMTGYVVTRWYRAPEVILNWMHYTQTVDIWSVGCIMAEMLTGKTLFKGNDHLDQLKEIMK
VTGTPPEEFVQRLQSEEAKTYMESLPELEKKDFASILTNASPLAVNLLEKMLVLDAQQRV
TAAEALAHPYFESLRDAEDDPKAQKYDESSDDMDRTLDEWKRITYKEVLSFKPPRQLGAK
VSKETAL
NT seq
1104 nt
NT seq
+upstream
nt +downstream
nt
atgagctcgccgccgcccgcgcgccggggcttctaccgccaggaggtgaccagcacggcc
tgggaggtgcgcgccgagtaccgcgacctgcagcccgtgggctcgggcgcctacggcgcc
gtgtgctcggccgtggacagccgctccggcgccaaggtggccatcaagaagctgtaccgg
cccttccagtccgcgctgttcgccaagcgcgcctaccgcgagctgcgcctcctcaagcac
atgcggcacgagaacgtgatcgggctgctggacgtcttcactccagacgagagcctggat
gacttcacggacttctacctggtgatgcccttcatgggcaccgacctgggcaagctcatg
aagcacgagcagctgagtgaggaccgcgtgcagttccttgtcttccagatgctgaagggg
ctgaagtacatccacgctgccggcgtcatccacagggacctgaagccgggcaacctggcg
gtgaacgaggactgtgagctgaagatcctggacttcggcctggccaggcaggcagacagc
gagatgaccgggtacgtggtcacccggtggtaccgggcgccagaggtcatcttgaattgg
atgcactatacacagacggtggacatctggtcggtgggctgcatcatggcggagatgctc
acgggcaagacgctgttcaagggcaacgaccacctggaccagctgaaggagatcatgaag
gtgaccggcacgccccccgaggagtttgtgcagcggctgcagagtgaggaggctaagacc
tacatggagagcctccccgagctggagaagaaggattttgcctccatcctgaccaacgcg
agtcctctggccgtgaacctcctggagaaaatgctggtgctggatgcgcagcagcgggtg
acggcggccgaggcactggcccacccctactttgagtcgctgcgggacgcggaggacgac
cccaaggcccagaagtacgacgagtcctctgacgacatggaccgcacgctggatgagtgg
aagcgtatcacgtataaagaggtgctcagcttcaagcctccccggcagctgggggccaaa
gtgtccaaggagacggccctgtga
DBGET
integrated database retrieval system