KEGG   Talpa occidentalis (Iberian mole): 119247241
Entry
119247241         CDS       T07495                                 
Symbol
ATF4
Name
(RefSeq) cyclic AMP-dependent transcription factor ATF-4
  KO
K04374  cyclic AMP-dependent transcription factor ATF-4
Organism
tod  Talpa occidentalis (Iberian mole)
Pathway
tod04010  MAPK signaling pathway
tod04022  cGMP-PKG signaling pathway
tod04137  Mitophagy - animal
tod04141  Protein processing in endoplasmic reticulum
tod04151  PI3K-Akt signaling pathway
tod04156  Integrated stress response (ISR) signaling pathway
tod04210  Apoptosis
tod04211  Longevity regulating pathway
tod04261  Adrenergic signaling in cardiomyocytes
tod04668  TNF signaling pathway
tod04720  Long-term potentiation
tod04722  Neurotrophin signaling pathway
tod04725  Cholinergic synapse
tod04728  Dopaminergic synapse
tod04911  Insulin secretion
tod04912  GnRH signaling pathway
tod04915  Estrogen signaling pathway
tod04918  Thyroid hormone synthesis
tod04922  Glucagon signaling pathway
tod04925  Aldosterone synthesis and secretion
tod04926  Relaxin signaling pathway
tod04927  Cortisol synthesis and secretion
tod04928  Parathyroid hormone synthesis, secretion and action
tod04932  Non-alcoholic fatty liver disease
tod04934  Cushing syndrome
tod04935  Growth hormone synthesis, secretion and action
tod05010  Alzheimer disease
tod05012  Parkinson disease
tod05014  Amyotrophic lateral sclerosis
tod05020  Prion disease
tod05022  Pathways of neurodegeneration - multiple diseases
tod05030  Cocaine addiction
tod05031  Amphetamine addiction
tod05034  Alcoholism
tod05161  Hepatitis B
tod05163  Human cytomegalovirus infection
tod05166  Human T-cell leukemia virus 1 infection
tod05203  Viral carcinogenesis
tod05207  Chemical carcinogenesis - receptor activation
tod05215  Prostate cancer
tod05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:tod00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    119247241 (ATF4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    119247241 (ATF4)
   04668 TNF signaling pathway
    119247241 (ATF4)
   04022 cGMP-PKG signaling pathway
    119247241 (ATF4)
   04151 PI3K-Akt signaling pathway
    119247241 (ATF4)
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    119247241 (ATF4)
  09143 Cell growth and death
   04210 Apoptosis
    119247241 (ATF4)
   04156 Integrated stress response (ISR) signaling pathway
    119247241 (ATF4)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    119247241 (ATF4)
   04922 Glucagon signaling pathway
    119247241 (ATF4)
   04912 GnRH signaling pathway
    119247241 (ATF4)
   04915 Estrogen signaling pathway
    119247241 (ATF4)
   04926 Relaxin signaling pathway
    119247241 (ATF4)
   04935 Growth hormone synthesis, secretion and action
    119247241 (ATF4)
   04918 Thyroid hormone synthesis
    119247241 (ATF4)
   04928 Parathyroid hormone synthesis, secretion and action
    119247241 (ATF4)
   04925 Aldosterone synthesis and secretion
    119247241 (ATF4)
   04927 Cortisol synthesis and secretion
    119247241 (ATF4)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    119247241 (ATF4)
  09156 Nervous system
   04725 Cholinergic synapse
    119247241 (ATF4)
   04728 Dopaminergic synapse
    119247241 (ATF4)
   04720 Long-term potentiation
    119247241 (ATF4)
   04722 Neurotrophin signaling pathway
    119247241 (ATF4)
  09149 Aging
   04211 Longevity regulating pathway
    119247241 (ATF4)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    119247241 (ATF4)
   05203 Viral carcinogenesis
    119247241 (ATF4)
  09162 Cancer: specific types
   05215 Prostate cancer
    119247241 (ATF4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    119247241 (ATF4)
   05161 Hepatitis B
    119247241 (ATF4)
   05163 Human cytomegalovirus infection
    119247241 (ATF4)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    119247241 (ATF4)
   05012 Parkinson disease
    119247241 (ATF4)
   05014 Amyotrophic lateral sclerosis
    119247241 (ATF4)
   05020 Prion disease
    119247241 (ATF4)
   05022 Pathways of neurodegeneration - multiple diseases
    119247241 (ATF4)
  09165 Substance dependence
   05030 Cocaine addiction
    119247241 (ATF4)
   05031 Amphetamine addiction
    119247241 (ATF4)
   05034 Alcoholism
    119247241 (ATF4)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    119247241 (ATF4)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    119247241 (ATF4)
   04934 Cushing syndrome
    119247241 (ATF4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:tod03000]
    119247241 (ATF4)
Transcription factors [BR:tod03000]
 Eukaryotic type
  Basic leucine zipper (bZIP)
   AP-1(-like) components, CRE-BP/ATF
    119247241 (ATF4)
SSDB
Motif
Pfam: bZIP_1 bZIP_2 CEP89 DUF3450 BNI5_helical DUF4407 Asd-4 OVT1 KIF21A AAA_13 DUF4192 NOCA1_mid Nop53
Other DBs
NCBI-GeneID: 119247241
NCBI-ProteinID: XP_037369419
LinkDB
Position
Unknown
AA seq 351 aa
MAEMSFLSSEVLVGDLMSPFDQSALGAEESLGLLDDYLEVAKHFKPHGFSGDKAKAGSSE
WLAVDGLVNASDIGKEDAFSGTDWMVEKIDLNEFDFDALLSLGDLETMPEELLASLDDTC
DLFDPLVQESNKEPPQIVNPIGHLPESLPKTDQVAPLTFLQPLPLSPGALSSTPDHSFSL
ELGSEVDISEGDRKPDSTAYVTMVPPCIKEEDSPSDNDSGICMSPEYLGSPQHSPPTSRS
SPNRSVIAPGVVCGPARPKPYDPPGEKIVAAKVKGEKLDKKLKKMEQNKTAATRYRQKKR
AEQEALTGECKELEKKNEALKERAESLAKEIQYLKDLIEEVRKARGKKKVP
NT seq 1056 nt   +upstreamnt  +downstreamnt
atggccgagatgagcttcctgagcagcgaggtgttggtgggggacttgatgtcccccttc
gaccagtcggctttgggggctgaagaaagcctgggtctcctggacgactacctggaggtg
gccaagcacttcaaacctcatgggttctccggcgacaaggctaaggcgggctcctccgag
tggctggctgtggatgggttggtcaacgcctcagacatcggcaaggaggatgccttctcc
gggacagattggatggtggagaaaatagatctgaatgagttcgactttgatgccctgttg
agtttaggtgacctggaaacgatgccagaggagcttttggcctcgctggatgacacgtgt
gatctctttgaccccctagtccaagagagtaataaggagcccccccagatagtgaacccc
attggccatcttccagaaagtttaccaaaaacagaccaggttgcccccttgacctttctg
caacctctccccctttccccaggggccctgtcttccactccagaccattcctttagttta
gagctaggcagtgaagtggacatctctgaaggagacaggaagccagactccacggcctat
gttaccatggtccctccgtgcatcaaggaggaggattccccctcagataacgatagtggt
atctgcatgagtcccgagtatctaggctctccccagcatagtccccccacctccaggagc
tctccaaacaggagtgtgatagccccaggtgtcgtttgtggccctgcccgccccaagccc
tatgaccctcctggagagaagattgtagcagcaaaagtaaaaggggagaaattggataag
aagctgaagaaaatggagcagaacaagaccgcagccactaggtaccgccagaagaagagg
gcagagcaggaggccctcactggcgagtgtaaagagctggagaagaagaacgaggctctg
aaggagcgggccgaatccctggccaaggagatccagtacctgaaagatctgatagaagag
gtccgcaaggcaaggggaaagaaaaaggttccctag

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