KEGG   Talpa occidentalis (Iberian mole): 119247590
Entry
119247590         CDS       T07495                                 
Symbol
PFKM
Name
(RefSeq) ATP-dependent 6-phosphofructokinase, muscle type isoform X1
  KO
K00850  6-phosphofructokinase 1 [EC:2.7.1.11]
Organism
tod  Talpa occidentalis (Iberian mole)
Pathway
tod00010  Glycolysis / Gluconeogenesis
tod00030  Pentose phosphate pathway
tod00051  Fructose and mannose metabolism
tod00052  Galactose metabolism
tod01100  Metabolic pathways
tod01200  Carbon metabolism
tod01230  Biosynthesis of amino acids
tod03018  RNA degradation
tod04066  HIF-1 signaling pathway
tod04152  AMPK signaling pathway
tod04919  Thyroid hormone signaling pathway
tod04922  Glucagon signaling pathway
tod05230  Central carbon metabolism in cancer
Module
tod_M00001  Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
Brite
KEGG Orthology (KO) [BR:tod00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    119247590 (PFKM)
   00030 Pentose phosphate pathway
    119247590 (PFKM)
   00051 Fructose and mannose metabolism
    119247590 (PFKM)
   00052 Galactose metabolism
    119247590 (PFKM)
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   03018 RNA degradation
    119247590 (PFKM)
 09130 Environmental Information Processing
  09132 Signal transduction
   04066 HIF-1 signaling pathway
    119247590 (PFKM)
   04152 AMPK signaling pathway
    119247590 (PFKM)
 09150 Organismal Systems
  09152 Endocrine system
   04922 Glucagon signaling pathway
    119247590 (PFKM)
   04919 Thyroid hormone signaling pathway
    119247590 (PFKM)
 09160 Human Diseases
  09161 Cancer: overview
   05230 Central carbon metabolism in cancer
    119247590 (PFKM)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:tod01009]
    119247590 (PFKM)
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:tod03019]
    119247590 (PFKM)
Enzymes [BR:tod01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.11  6-phosphofructokinase
     119247590 (PFKM)
Protein phosphatases and associated proteins [BR:tod01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     119247590 (PFKM)
Messenger RNA biogenesis [BR:tod03019]
 Prokaryotic type
  Bacterial mRNA degradation factors
   RNA degradosome components
    Other RNA degradosome components
     119247590 (PFKM)
SSDB
Motif
Pfam: PFK
Other DBs
NCBI-GeneID: 119247590
NCBI-ProteinID: XP_037370042
LinkDB
Position
Unknown
AA seq 849 aa
MHREEFHLKFFMCVIQSRQLVSTPQRTAGEASTSSIQKPPPDTDVLKSIYTVDDADTMEG
IPIVKHDWIMTHEEHHAAKTLGIGKAIAVLTSGGDAQGMNAAVRAVVRVGIFTGARVFFV
HEGYQGLVDGGDHIREATWESVSMMLQLGGTVIGSARCKDFREREGRLRAAQNLVKRGIT
NLCVIGGDGSLTGADTFRSEWSGLLSDLQKSGKITAEEAKKSSYLNIVGLVGSIDNDFCG
TDMTIGTDSALHRIIEIVDAITTTAQSHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIP
ECPPDDDWEEHLCRRLSETRTRGSRLNIIIVAEGAIDKNGKPITSEDIKNLVVKRLGYDT
RVTVLGHVQRGGTPSAFDRILGSRMGVEAVMALLEGTPDTPACVVSLSGNQAVRLPLMEC
VQVTKDVTKAMDEKKFDEAMKLRGRSFMNNWEVYKLLAHVRPPVSKTGLHTVAVMNVGAP
AAGMNAAVRSTVRIGLIQGNRVLVVHDGFEGLAKGQIEEAGWSYVGGWTGQGGSKLGTKR
TLPKKSFEQISANITKFNIQGLIIIGGFEAYTGGLELMEGRKQFDELCIPFVVIPATVSN
NVPGSDFSIGADTALNTICTTCDRIKQSAAGTKRRVFIIETMGGYCGYLATMAGLAAGAD
AAYIFEEPFTIRDLQANVEHLVQKMKTTVKRGLVLRNEKCNENYTTDFIFNLYSEEGKGI
FDSRKNVLGHMQQGGSPTPFDRNFATKMGAKAMNWMSGKIKESYRNGRIFANTPDSGCVL
GMRKRALVFQPVTELKDQTDFEHRIPKEQWWLKLRPILKILAKYEIDLDTSEHAHLEHIS
RKRSGEAPV
NT seq 2550 nt   +upstreamnt  +downstreamnt
atgcatagagaagaatttcatctgaaatttttcatgtgtgtgattcaatctcggcagtta
gtcagcactcctcagagaacagctggggaagcttcaacttccagcatacagaagccacca
ccagacacagatgtcttgaagagtatatacactgtggatgatgcagataccatggaaggc
atacctattgtgaaacatgattggatcatgacccatgaagagcaccatgcagccaagacc
ctggggattggcaaagccattgctgtgctaacctctggtggagatgcccaaggtatgaat
gctgctgttagggctgtggttcgtgttggaatctttactggagcccgtgtcttctttgtc
catgagggttatcaaggcctggtggatggcggagaccacatcagggaagccacctgggag
agtgtttcgatgatgctccagctgggaggcacagtgattggaagtgcccggtgcaaggac
tttcgggagcgagagggaagacttcgtgctgcccaaaacttggtgaagcgtgggattacc
aatctgtgtgttattgggggtgatggcagtctcactggggctgacaccttccgctctgag
tggagtggcttgttgagtgacctccagaaatctggtaagatcacagctgaggaggccaag
aaatccagctacctgaacatcgtgggcctggtgggctccattgacaatgacttttgcggc
actgatatgaccattggtactgactctgccctgcaccggatcatagagattgtagatgct
atcaccaccactgctcagagccaccagaggacatttgtgctagaagtgatgggccggcac
tgtggctacctggcccttgttacctctctttcctgtggggctgactgggtttttattcct
gaatgtccaccagatgatgactgggaggaacatctttgtcgccggctcagtgagacaagg
acacgtggctctcgtctcaacatcatcattgtggctgagggtgccattgacaagaatggg
aaaccaatcacctcagaagacatcaagaatctggtggtgaaacgtctgggatatgatacc
cgggtcaccgtcttagggcatgtgcagcggggtggaaccccatcagcctttgaccgaatc
ctgggcagcaggatgggtgtagaagcagtgatggcacttttggaggggaccccagacacc
ccagcctgtgtagtgagcctctctggtaaccaggctgtgcgcctgcccctcatggaatgt
gtacaggtgaccaaagatgtgaccaaggccatggatgagaagaaatttgatgaagccatg
aagttgagaggccggagtttcatgaacaactgggaagtgtacaagcttctggctcatgtc
aggcccccagtatctaagactggtttgcacacagtggctgtgatgaatgtgggggccccg
gccgcaggaatgaatgctgctgttcgctccactgtgaggattggcctcatccagggcaac
cgagtgctggtcgtgcatgatggcttcgagggtctggccaagggtcagattgaggaggct
ggttggagctacgtcgggggctggactggccaaggtggttctaaacttgggactaaaagg
acactgcccaagaagagctttgaacagatcagtgctaacattacaaagtttaacattcag
ggccttatcatcatcggaggctttgaggcttacacggggggcctggagctgatggagggc
aggaagcagttcgacgagctctgtatcccctttgtggtcattcctgctacggtctccaac
aacgtccctggctcagacttcagcatcggggcggacacagcactgaacacgatttgcacg
acctgtgaccgcatcaagcagtcagcggcaggcaccaagcgccgggtgtttatcatcgag
accatgggcggctactgcggctacctggccaccatggcagggctggcagcgggggctgat
gctgcctacatttttgaggagccctttaccatccgagacctgcaggcaaatgttgaacat
ctggtgcaaaagatgaaaacaactgtgaaaaggggtttggtgttaaggaatgagaagtgc
aatgagaactataccaccgacttcattttcaacctgtactctgaggagggaaagggcatc
ttcgacagcaggaagaacgtgcttggccacatgcagcagggtgggagcccaaccccattt
gacagaaattttgccactaagatgggtgccaaagctatgaactggatgtccgggaaaatc
aaagagagctaccgtaacggacggatctttgccaataccccagactctggctgtgtcctg
gggatgcgtaagagggccctggtttttcaacctgtgactgagttgaaggaccagacagat
tttgagcatcgcatccccaaggaacagtggtggctgaagctgaggcccatcctcaaaatt
ctagccaagtatgagattgacttggacacctcagagcatgcccacctggagcacatcagt
cggaagcggtctggagaagctcctgtctaa

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