Talpa occidentalis (Iberian mole): 119248080
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Entry
119248080 CDS
T07495
Symbol
SHMT2
Name
(RefSeq) LOW QUALITY PROTEIN: serine hydroxymethyltransferase, mitochondrial
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
tod
Talpa occidentalis (Iberian mole)
Pathway
tod00260
Glycine, serine and threonine metabolism
tod00630
Glyoxylate and dicarboxylate metabolism
tod00670
One carbon pool by folate
tod01100
Metabolic pathways
tod01200
Carbon metabolism
tod01230
Biosynthesis of amino acids
tod01240
Biosynthesis of cofactors
tod01523
Antifolate resistance
tod04981
Folate transport and metabolism
Module
tod_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
tod00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
119248080 (SHMT2)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
119248080 (SHMT2)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
119248080 (SHMT2)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
119248080 (SHMT2)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
119248080 (SHMT2)
Enzymes [BR:
tod01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
119248080 (SHMT2)
BRITE hierarchy
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Ortholog
Paralog
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Motif
Pfam:
SHMT
Motif
Other DBs
NCBI-GeneID:
119248080
NCBI-ProteinID:
XP_037370939
LinkDB
All DBs
Position
Unknown
AA seq
504 aa
AA seq
DB search
MLPFSLLWATRPLRRCGQLGRPALRGQHREAARTQTGEATRGWTGQESLSESDPQVWELL
QREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQ
RRALEAFDLDPAQWGVNVQPYSGSPANLAAYTALLQPHDRIMGLDLPDGGHLTHGYMSDV
KRISATSIFFESMPYKLNPQTGLIDYEQLALTARLFRPRLLIAGTSAYARLIDYARMREV
CDEVRAHLLADMAHISGLVAAKVIPSPFEHADVVTTTTHKTLRGARSGLIFYRKGVRTVD
PKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNAKA
MADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSALT
PXGLRLGAPALTSRQFREDDFRRVVGFIDEGVGIGLEVKSKTAKLQDFKSFLLSDPETRH
QLADLRQRVERFARAFPMPGFEEH
NT seq
1515 nt
NT seq
+upstream
nt +downstream
nt
atgctgcccttctccctgctgtgggcgactcggccgctgcggagatgtggtcagctgggg
aggccggccctgcggggccagcaccgtgaggcggcccggacccagactggagaagccacc
aggggctggacaggccaggagagcctgtcagaaagtgaccctcaggtgtgggagctgctg
cagagggagaaggacaggcagtgccgtggcctggaactcatcgcctcagagaacttctgc
agccgagctgcgctggaggccctggggtcctgtctgaacaacaagtactcggagggatat
cctggcaagagatattatgggggagcagaggtggtggatgaaattgagctgctgtgtcag
cgccgggccttggaggcctttgacctggatcctgcgcagtggggagtcaatgtccagccc
tactcgggctccccggccaacctggccgcctacacagcccttctgcagcctcacgaccga
atcatgggcctggacctgcctgatgggggccatctcactcacggctacatgtctgacgtc
aagcggatctcagccacatccatcttcttcgagtctatgccctacaagctgaacccccag
accggcctcatcgactacgagcagctggcgctgaccgctcgacttttccggccgaggctc
ctcatcgccggcaccagcgcctacgcccgcctcattgactacgcgcgaatgagagaggtg
tgtgatgaggtccgcgcacacctgctggcggacatggcccacataagcggcctggtggcg
gccaaggtgatcccctcccctttcgagcatgcggacgtcgtcaccaccaccacgcacaag
accctgcggggggccaggtcagggctcatcttctaccggaagggggtacggactgtggac
cctaagactggccgcgagatcccgtacacgttcgaggaccgaatcaactttgccgtgttc
ccttccctgcaagggggcccccacaaccacgccatcgccgccgtggctgtggccctgaag
caggcctgcacccccatgttccgggagtattctctgcaggttctgaagaacgccaaggcc
atggcggacgccctgctggagcggggctactcgctggtgtcgggtggcaccgacaaccac
ctcgtgctggtggaccttcggcccaagggcctggacggggctcgggccgagcgggtgctg
gagctcgtgtccatcacggccaacaagaacacctgccccggagaccggagcgcgctcacg
cccnggggcctgcggctcggggcccccgccttgacctcccggcagttccgtgaggatgac
ttccgccgagtcgtgggcttcatcgatgaaggtgtcggcattggcttggaggtgaagagc
aagacggccaagctccaggacttcaaatccttcctgctcagcgacccagaaaccagacat
cagctggctgacctcaggcagcgggtggagcgctttgccagggccttccccatgcctggc
ttcgaggagcactga
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