Talpa occidentalis (Iberian mole): 119248120
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Entry
119248120 CDS
T07495
Symbol
TBK1
Name
(RefSeq) serine/threonine-protein kinase TBK1 isoform X1
KO
K05410
TANK-binding kinase 1 [EC:
2.7.11.10
]
Organism
tod
Talpa occidentalis (Iberian mole)
Pathway
tod04014
Ras signaling pathway
tod04137
Mitophagy - animal
tod04140
Autophagy - animal
tod04620
Toll-like receptor signaling pathway
tod04621
NOD-like receptor signaling pathway
tod04622
RIG-I-like receptor signaling pathway
tod04623
Cytosolic DNA-sensing pathway
tod04657
IL-17 signaling pathway
tod04936
Alcoholic liver disease
tod05014
Amyotrophic lateral sclerosis
tod05022
Pathways of neurodegeneration - multiple diseases
tod05135
Yersinia infection
tod05160
Hepatitis C
tod05161
Hepatitis B
tod05162
Measles
tod05163
Human cytomegalovirus infection
tod05164
Influenza A
tod05165
Human papillomavirus infection
tod05167
Kaposi sarcoma-associated herpesvirus infection
tod05168
Herpes simplex virus 1 infection
tod05169
Epstein-Barr virus infection
tod05170
Human immunodeficiency virus 1 infection
tod05171
Coronavirus disease - COVID-19
tod05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
tod00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
119248120 (TBK1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
119248120 (TBK1)
04137 Mitophagy - animal
119248120 (TBK1)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
119248120 (TBK1)
04621 NOD-like receptor signaling pathway
119248120 (TBK1)
04622 RIG-I-like receptor signaling pathway
119248120 (TBK1)
04623 Cytosolic DNA-sensing pathway
119248120 (TBK1)
04657 IL-17 signaling pathway
119248120 (TBK1)
09160 Human Diseases
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
119248120 (TBK1)
05161 Hepatitis B
119248120 (TBK1)
05160 Hepatitis C
119248120 (TBK1)
05171 Coronavirus disease - COVID-19
119248120 (TBK1)
05164 Influenza A
119248120 (TBK1)
05162 Measles
119248120 (TBK1)
05168 Herpes simplex virus 1 infection
119248120 (TBK1)
05163 Human cytomegalovirus infection
119248120 (TBK1)
05167 Kaposi sarcoma-associated herpesvirus infection
119248120 (TBK1)
05169 Epstein-Barr virus infection
119248120 (TBK1)
05165 Human papillomavirus infection
119248120 (TBK1)
09171 Infectious disease: bacterial
05135 Yersinia infection
119248120 (TBK1)
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
119248120 (TBK1)
05022 Pathways of neurodegeneration - multiple diseases
119248120 (TBK1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
119248120 (TBK1)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
119248120 (TBK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
tod01001
]
119248120 (TBK1)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
tod04131
]
119248120 (TBK1)
Enzymes [BR:
tod01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.10 IkappaB kinase
119248120 (TBK1)
Protein kinases [BR:
tod01001
]
Serine/threonine kinases: Other
IKK family [OT]
119248120 (TBK1)
Membrane trafficking [BR:
tod04131
]
Autophagy
Xenophagy
Other xenophagy associated proteins
119248120 (TBK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
TBK1_CCD1
Pkinase
TBK1_ULD
PK_Tyr_Ser-Thr
Pkinase_fungal
ABC1
Kinase-like
DUF713
CEP63
Motif
Other DBs
NCBI-GeneID:
119248120
NCBI-ProteinID:
XP_037371011
LinkDB
All DBs
Position
Unknown
AA seq
729 aa
AA seq
DB search
MQSTSNHLWLLSDILGQGATANVFRGRHKKTGDLFAIKVFNNISFLRPVDVQMREFEVLK
KLNHKNIVKLFAIEEETTTRHKVLVMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVV
GGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDEQFVSLYGTEEYL
HPDMYERAVLRKDHQKKYGATVDLWSIGVTFYHAATGSLPFRPFEGPRRNKEVMYKIITG
KPSGAISGVQKAENGPIDWSGDMPVSCSLSRGLQVLLTPVLANILEADQEKCWGFDQFFA
ETSDILHRMIIHVFSLQQMTAHKIYIHTYNTDTVFHELVYKQTKIISSNQELIYEGRRLV
LEPGTLAQHFPKTTEENPIFVVSRESLNTVGLKYEKISLPKVHPRYDLDGDASMAKAITG
VVCYACRVASTLLLYQELMRKGIRWLIELVKDDYNETVHKKTEVVITLDFCIRNIEKTVK
VYEKLMKVNLEAAELGEISDIHTKLLRLSSSQGTIETSLQDIESRLSPGGLLADAWAHQE
GTHPKDRHVEKLQVLLNCITEIYYQFKKDKAERRLAYNEEQIHKFDKQKLYYHATKAMTH
FTDECVKKYEAFFDKSEEWMRKMLHLRKQLLSLTNQCFDIEEEVSKYQDYTNELQETLPQ
KMFAASSGIKHAMTPVYPCSNTLVEMTLGMKKLKEEMEGVVKELAENNHILERFGSLTMD
GGLRNVDCL
NT seq
2190 nt
NT seq
+upstream
nt +downstream
nt
atgcagagcacttctaatcacttgtggcttttatctgatattttaggccaaggagctact
gcaaatgtctttcgtggacgacataagaaaactggtgacttatttgctatcaaagtattt
aataacataagcttcctacgtccagtggatgttcaaatgagagaatttgaagtgttaaaa
aaactcaatcataaaaatattgtcaaattatttgctattgaagaggagacaacaacaaga
cataaagtacttgttatggaattttgtccatgcgggagtttatacactgtcttagaagag
ccatctaatgcctacggactaccggagtctgaatttttaattgttttgcgagatgtggtg
ggtggaatgaatcatctccgagagaacggcattgtgcaccgagacatcaagccgggaaat
atcatgcgtgtcatcggggaggacggacagtctgtgtacaaactcacagattttggtgca
gctcgagagttagaagatgatgagcagtttgtttcactgtatggcacggaagaatacttg
caccctgacatgtacgagagagcagtgctgaggaaagaccaccagaagaaatatggcgcc
acggtggacctctggagcatcggggtgacgttctaccacgcggccacagggtcgctgcca
tttaggccgtttgaagggccacgcaggaataaggaagtgatgtacaaaataattactgga
aagccttctggtgcaatatctggggtgcagaaagcagagaatggaccaattgactggagt
ggagacatgcctgtttcttgtagcctttctcggggacttcaagtactccttacccccgtt
ctggcaaacatccttgaggcagatcaggaaaagtgttggggttttgaccagttttttgca
gaaacaagtgacatacttcaccgaatgataattcatgttttttcactacaacaaatgaca
gctcataagatttatattcatacctataatactgatactgtatttcatgaactggtctat
aaacaaaccaaaattatttcttccaatcaagaacttatatatgaaggaagacgcttagtt
ctagaaccaggaactctggcccagcattttcctaaaactactgaggaaaatcccatcttt
gtagtaagccgagaatctctgaataccgtaggactgaaatatgaaaaaatttccctccct
aaagtacacccacgttacgacttggatggggacgctagcatggctaaggcaataacagga
gttgtgtgttacgcctgcagagtggccagcaccttgctgctttaccaggagttaatgcga
aaggggatacgatggttaatagaattagttaaagatgattataatgaaactgttcacaaa
aagacagaagttgtgatcacactggatttctgcatcagaaacattgaaaaaactgtgaaa
gtgtatgaaaagttgatgaaggtcaacctagaagcagcagagttaggtgaaatttcagac
atacacaccaaattgttgagactttccagttctcagggaacaatagaaaccagtcttcag
gatatcgaaagcagattatctccaggtggattgctggcagatgcgtgggcccaccaagaa
ggcactcatccaaaagacagacatgtagaaaagctacaagtcttgttaaattgcatcaca
gagatttactatcagttcaaaaaagacaaagcagaacgtcgactagcttataatgaagaa
caaatccataaattcgataagcaaaaactgtattaccatgcaacaaaggctatgacccac
ttcacagatgaatgtgttaaaaaatatgaggcattttttgataagtcagaagaatggatg
agaaagatgcttcatcttaggaaacagttattgtccctgacgaatcagtgttttgatatt
gaagaagaagtgtccaagtatcaagactacaccaatgagttacaagaaactttacctcag
aaaatgtttgcagcctccagtggaatcaaacatgccatgaccccagtttacccctgttct
aacacattagtggaaatgactcttggtatgaagaaattaaaagaagaaatggaaggggtg
gttaaagaacttgctgaaaacaatcatattttggaaagatttggctctttaaccatggat
ggtggccttcgaaatgttgactgtctttag
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