Talpa occidentalis (Iberian mole): 119249160 Help Entry 119249160         CDS       T07495                                  Symbol ADCY7 Name (RefSeq) adenylate cyclase type 7   KO K08047   adenylate cyclase 7 [EC:4.6.1.1] Organism tod  Talpa occidentalis (Iberian mole) Pathway tod00230   Purine metabolism tod01100   Metabolic pathways tod01522   Endocrine resistance tod04015   Rap1 signaling pathway tod04020   Calcium signaling pathway tod04022   cGMP-PKG signaling pathway tod04024   cAMP signaling pathway tod04062   Chemokine signaling pathway tod04072   Phospholipase D signaling pathway tod04081   Hormone signaling tod04082   Neuroactive ligand signaling tod04114   Oocyte meiosis tod04211   Longevity regulating pathway tod04213   Longevity regulating pathway - multiple species tod04261   Adrenergic signaling in cardiomyocytes tod04270   Vascular smooth muscle contraction tod04371   Apelin signaling pathway tod04540   Gap junction tod04611   Platelet activation tod04713   Circadian entrainment tod04714   Thermogenesis tod04723   Retrograde endocannabinoid signaling tod04724   Glutamatergic synapse tod04725   Cholinergic synapse tod04727   GABAergic synapse tod04750   Inflammatory mediator regulation of TRP channels tod04911   Insulin secretion tod04912   GnRH signaling pathway tod04913   Ovarian steroidogenesis tod04914   Progesterone-mediated oocyte maturation tod04915   Estrogen signaling pathway tod04916   Melanogenesis tod04918   Thyroid hormone synthesis tod04921   Oxytocin signaling pathway tod04923   Regulation of lipolysis in adipocytes tod04925   Aldosterone synthesis and secretion tod04926   Relaxin signaling pathway tod04927   Cortisol synthesis and secretion tod04928   Parathyroid hormone synthesis, secretion and action tod04934   Cushing syndrome tod04935   Growth hormone synthesis, secretion and action tod04970   Salivary secretion tod04971   Gastric acid secretion tod04972   Pancreatic secretion tod04976   Bile secretion tod05032   Morphine addiction tod05163   Human cytomegalovirus infection tod05166   Human T-cell leukemia virus 1 infection tod05200   Pathways in cancer tod05207   Chemical carcinogenesis - receptor activation tod05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:tod00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     119249160 (ADCY7)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     119249160 (ADCY7)    04371 Apelin signaling pathway     119249160 (ADCY7)    04020 Calcium signaling pathway     119249160 (ADCY7)    04072 Phospholipase D signaling pathway     119249160 (ADCY7)    04024 cAMP signaling pathway     119249160 (ADCY7)    04022 cGMP-PKG signaling pathway     119249160 (ADCY7)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     119249160 (ADCY7)    04081 Hormone signaling     119249160 (ADCY7)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     119249160 (ADCY7)   09144 Cellular community - eukaryotes    04540 Gap junction     119249160 (ADCY7)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     119249160 (ADCY7)    04062 Chemokine signaling pathway     119249160 (ADCY7)   09152 Endocrine system    04911 Insulin secretion     119249160 (ADCY7)    04923 Regulation of lipolysis in adipocytes     119249160 (ADCY7)    04912 GnRH signaling pathway     119249160 (ADCY7)    04913 Ovarian steroidogenesis     119249160 (ADCY7)    04915 Estrogen signaling pathway     119249160 (ADCY7)    04914 Progesterone-mediated oocyte maturation     119249160 (ADCY7)    04921 Oxytocin signaling pathway     119249160 (ADCY7)    04926 Relaxin signaling pathway     119249160 (ADCY7)    04935 Growth hormone synthesis, secretion and action     119249160 (ADCY7)    04918 Thyroid hormone synthesis     119249160 (ADCY7)    04928 Parathyroid hormone synthesis, secretion and action     119249160 (ADCY7)    04916 Melanogenesis     119249160 (ADCY7)    04925 Aldosterone synthesis and secretion     119249160 (ADCY7)    04927 Cortisol synthesis and secretion     119249160 (ADCY7)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     119249160 (ADCY7)    04270 Vascular smooth muscle contraction     119249160 (ADCY7)   09154 Digestive system    04970 Salivary secretion     119249160 (ADCY7)    04971 Gastric acid secretion     119249160 (ADCY7)    04972 Pancreatic secretion     119249160 (ADCY7)    04976 Bile secretion     119249160 (ADCY7)   09156 Nervous system    04724 Glutamatergic synapse     119249160 (ADCY7)    04727 GABAergic synapse     119249160 (ADCY7)    04725 Cholinergic synapse     119249160 (ADCY7)    04723 Retrograde endocannabinoid signaling     119249160 (ADCY7)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     119249160 (ADCY7)   09149 Aging    04211 Longevity regulating pathway     119249160 (ADCY7)    04213 Longevity regulating pathway - multiple species     119249160 (ADCY7)   09159 Environmental adaptation    04713 Circadian entrainment     119249160 (ADCY7)    04714 Thermogenesis     119249160 (ADCY7)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     119249160 (ADCY7)    05207 Chemical carcinogenesis - receptor activation     119249160 (ADCY7)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     119249160 (ADCY7)    05163 Human cytomegalovirus infection     119249160 (ADCY7)   09165 Substance dependence    05032 Morphine addiction     119249160 (ADCY7)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     119249160 (ADCY7)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     119249160 (ADCY7)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     119249160 (ADCY7) Enzymes [BR:tod01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      119249160 (ADCY7) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom AC_N Motif Other DBs NCBI-GeneID:  119249160 NCBI-ProteinID:  XP_037372181 LinkDB All DBs Position Unknown AA seq 1076 aa AA seqDB search MCQHQRMPAKGRYFLNEGEEVPGHDVLYEKYRLTSQHGPLLLTLLLVAITACIGLVTIAF TDGGFPRHHPILVTAFLILAVFAVLYVLVYFEYLVQRWLRVFALLTWACLMTLGYVLVYD SRINEDCVQSLQVPFFLFIIFVVYTLLPFSMWGAVAVGVVSSVSYLLVAVVALNAFTMTQ MLACTVIFLCGNLTGAFHKHQMHDASRDLFIYTVKCIQIRRKLRIEKRQQENLLLSVLPA HISMGMKLTIIERLKEGGDRRYMPDNNFHSLYVKRHQNVSILYADIVGFTRLASDCSPKE LVVVLNELFGKFDQIAKANECMRIKILGDCYYCVSGLPVSLPTHARNCVKMGLDICEAIK QVREATGVDISMRVGIHSGNVLCGVIGLRKWQYDVWSHDVSLANRMEAAGVPGRVHITEA TLNHLDKAYEVEDGHGQQRDPYLKEMNISTYLVIDPRSQQPPPPSQHLHKPKGDTALKMR ASVRMTRYLESWGAARPFAHLNHRESMSSNETPVPRRRRPKAIPLRRHRNPDRSASPKGR LEDDSYDDEMLSAIEGLSSTRPCCSKSDDFYSIGSFFREKDFEREYRLAPIPRVRNYFAC ASLIFVCILLVHVLLMPRTKDLGITFGLVACVLALVLGLCFANEFLRCCPAQGVLRAISE SVETQPLLRLFLAILTVSSLLTIAVINLKLTAYSNGTEPSLSNPSDRNQCQCLEADQCEH LLFYTCSCMLAFIACSVFLRMSLELKVVLLTAALGAYLVLFNQNKNISLCFQQNCSSNST DWCSTCPSSSLNMMIDFYLALFYATLIMLSRQIDYYCRLDCLWKKKFKKEHEEFETMENV NRLLLENVLPAHVAAHFIGDKLNEDWYHQSYDCVCVMFASVPDFKVFYTECDVNKEGLEC LRLLNEIIADFDELLLKPKFSGVEKIKTIGSTYMAAAGLSIPSGHENQDLARQHAHIGIM VEFSIALMSKLDGINRHSFNSFRLRVGINHGPVIAGVIGARKPQYDIWGNTVNVASRMES TGELGKIQVTEETCTILQGLGYSCECRGLINVKGKGELRTYFVCTDTTKFQGSGLN NT seq 3231 nt NT seq  +upstreamnt  +downstreamnt atgtgccaacaccaaaggatgccggccaaggggcgctacttcctcaatgaaggtgaggag gtcccaggccatgatgtactgtatgagaagtaccgcctcaccagccagcatgggccgctg ttgctcacactccttttggtggccatcactgcctgcattggcctcgtcaccatcgccttc accgatgggggattccccagacaccaccctatcctggtgacggcgttcttgatacttgct gtgtttgcggtgctctacgtactggtgtattttgagtaccttgtgcagcggtggctcagg gtcttcgcactactcacctgggcctgccttatgacactaggctatgtgctggtgtacgac tcaaggataaacgaagactgtgtacaatcattgcaggtgccctttttcctgttcatcatc ttcgtggtgtacacactgctgcctttcagcatgtggggagccgttgctgtgggggtggtc tccagcgtctcctacctcctggtggccgttgtggcattgaatgccttcaccatgacgcag atgctggcctgcactgtcatcttcctgtgcgggaacctcacgggcgcctttcacaagcac cagatgcatgatgcctcccgggacctcttcatctacactgtgaagtgcatccagatcaga cgtaagctgcgcatcgagaagcgccagcaggagaacctgctactgtcagtgctgccggcc cacatctccatgggcatgaagctgaccatcattgagcggctcaaggagggtggggaccgc cgctacatgccggacaacaacttccacagcctctacgtcaaacggcaccagaatgtcagc atcctatacgctgatattgtgggcttcacgagactggccagtgactgctcccccaaagag ctggtggtggtgctgaatgagctcttcggcaagtttgaccagatcgccaaggccaatgag tgcatgaggatcaagatcctgggtgactgctactactgcgtgtcaggcctgccggtgtcc ttgcccacccacgcccggaactgtgtgaagatggggctggacatatgtgaggctattaag caggtgcgggaggcgacgggtgtggacatcagcatgcgtgtgggcatacactcggggaac gtgctgtgcggcgtcatcgggctgcgcaagtggcagtacgacgtctggtcccacgatgtg tccctggccaataggatggaggcggctggagtccctggccgggtacatatcacagaggcg acactgaaccacctggacaaggcatatgaggtggaggacgggcacgggcagcagcgagac ccctacctgaaagagatgaacatcagcacctacctggtcatcgacccccggagccagcag ccacccccgcctagccaacacctccataagcccaagggggacacagctctgaagatgagg gcctctgtgcgcatgacccgctacctcgagtcctggggggcagcgaggccctttgcacac ctcaaccatcgcgagagtatgagcagcaacgagacccctgtccctagaaggcggaggcct aaggccattcccctgcggcgccaccggaaccctgacagaagtgcatcccccaaagggcgg ttggaagatgactcctatgatgacgaaatgctgtcagcaattgaggggctcagctccaca cgaccctgctgctccaaatctgatgacttctacagcatcgggtccttcttccgggagaag gactttgagcgagagtaccgcctggcgcccatcccccgggtccgcaactactttgcctgc gccagcctcatctttgtctgcatcctacttgtccacgtcctgctgatgcccaggacaaaa gatctgggtataacctttgggctggtggcctgcgtgctggcacttgtgctaggcctgtgc tttgccaatgagtttttgaggtgctgcccagcccagggggtgctccgggccatctctgag agtgtggagacacagcccctgctgcgcctgttcctggccatcctgactgtcagcagcctg ctcaccattgccgtcatcaacctgaagctgacagcttatagcaatgggacagaaccgagc ctttcaaacccctcggacagaaaccaatgtcagtgcctggaggctgaccagtgtgagcat ctcctgttctacacctgcagctgcatgctggcctttatcgcctgctctgtcttcctgcgg atgagcctggagctgaaggttgtgctgttgactgcagccttgggggcctacctggtactc ttcaaccaaaacaaaaacatcagcctgtgctttcagcagaactgcagcagcaacagcact gattggtgttcaacctgtccaagtagtagtctgaatatgatgatcgatttctacctggct ctgttctacgccaccctcatcatgctctccagacaaattgactattactgccgcttggat tgtctgtggaagaagaagttcaagaaggagcatgaggagtttgagaccatggagaacgta aaccggcttcttctggagaatgtcctgccagcccacgtggctgcccacttcattggtgac aagttaaatgaggactggtaccatcagtcctatgactgcgtctgcgtcatgtttgcgtca gtgccagacttcaaagtattctacacggagtgcgacgtcaacaaggaagggctggagtgc ctgcgcctgctcaatgagatcatcgcggacttcgacgagctgctattaaagcccaagttc agtggcgtggagaagatcaagaccatcggcagcacgtatatggcggctgccgggctcagc atcccctcgggtcatgagaaccaggacctggctcggcagcatgcccatatcggtatcatg gtggagttcagcatcgccctgatgagcaaactggatggcatcaacagacactccttcaac tccttccgcctccgagttggcatcaaccatgggcctgtgattgctggagtgatcggggca cgaaagcctcagtatgacatctgggggaacacggtcaacgtggccagccggatggaaagc actggagaactggggaaaatccaggttactgaagagacatgcaccatcctccagggacta ggttactcttgtgaatgccgaggactgattaatgtcaaaggcaaaggtgaactgcggact tactttgtctgtacagataccaccaagtttcaaggatcagggctgaactga

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