Talpa occidentalis (Iberian mole): 119249909
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Entry
119249909 CDS
T07495
Symbol
RPS6KB2
Name
(RefSeq) ribosomal protein S6 kinase beta-2 isoform X1
KO
K04688
ribosomal protein S6 kinase beta [EC:
2.7.11.1
]
Organism
tod
Talpa occidentalis (Iberian mole)
Pathway
tod01521
EGFR tyrosine kinase inhibitor resistance
tod01522
Endocrine resistance
tod04012
ErbB signaling pathway
tod04066
HIF-1 signaling pathway
tod04140
Autophagy - animal
tod04150
mTOR signaling pathway
tod04151
PI3K-Akt signaling pathway
tod04152
AMPK signaling pathway
tod04211
Longevity regulating pathway
tod04213
Longevity regulating pathway - multiple species
tod04350
TGF-beta signaling pathway
tod04371
Apelin signaling pathway
tod04666
Fc gamma R-mediated phagocytosis
tod04714
Thermogenesis
tod04910
Insulin signaling pathway
tod04931
Insulin resistance
tod05163
Human cytomegalovirus infection
tod05165
Human papillomavirus infection
tod05170
Human immunodeficiency virus 1 infection
tod05200
Pathways in cancer
tod05205
Proteoglycans in cancer
tod05207
Chemical carcinogenesis - receptor activation
tod05210
Colorectal cancer
tod05212
Pancreatic cancer
tod05221
Acute myeloid leukemia
tod05224
Breast cancer
tod05225
Hepatocellular carcinoma
tod05226
Gastric cancer
tod05231
Choline metabolism in cancer
tod05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
tod00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
119249909 (RPS6KB2)
04350 TGF-beta signaling pathway
119249909 (RPS6KB2)
04371 Apelin signaling pathway
119249909 (RPS6KB2)
04066 HIF-1 signaling pathway
119249909 (RPS6KB2)
04151 PI3K-Akt signaling pathway
119249909 (RPS6KB2)
04152 AMPK signaling pathway
119249909 (RPS6KB2)
04150 mTOR signaling pathway
119249909 (RPS6KB2)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
119249909 (RPS6KB2)
09150 Organismal Systems
09151 Immune system
04666 Fc gamma R-mediated phagocytosis
119249909 (RPS6KB2)
09152 Endocrine system
04910 Insulin signaling pathway
119249909 (RPS6KB2)
09149 Aging
04211 Longevity regulating pathway
119249909 (RPS6KB2)
04213 Longevity regulating pathway - multiple species
119249909 (RPS6KB2)
09159 Environmental adaptation
04714 Thermogenesis
119249909 (RPS6KB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
119249909 (RPS6KB2)
05205 Proteoglycans in cancer
119249909 (RPS6KB2)
05207 Chemical carcinogenesis - receptor activation
119249909 (RPS6KB2)
05231 Choline metabolism in cancer
119249909 (RPS6KB2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
119249909 (RPS6KB2)
09162 Cancer: specific types
05210 Colorectal cancer
119249909 (RPS6KB2)
05212 Pancreatic cancer
119249909 (RPS6KB2)
05225 Hepatocellular carcinoma
119249909 (RPS6KB2)
05226 Gastric cancer
119249909 (RPS6KB2)
05221 Acute myeloid leukemia
119249909 (RPS6KB2)
05224 Breast cancer
119249909 (RPS6KB2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
119249909 (RPS6KB2)
05163 Human cytomegalovirus infection
119249909 (RPS6KB2)
05165 Human papillomavirus infection
119249909 (RPS6KB2)
09167 Endocrine and metabolic disease
04931 Insulin resistance
119249909 (RPS6KB2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
119249909 (RPS6KB2)
01522 Endocrine resistance
119249909 (RPS6KB2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
tod01001
]
119249909 (RPS6KB2)
Enzymes [BR:
tod01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
119249909 (RPS6KB2)
Protein kinases [BR:
tod01001
]
Serine/threonine kinases: AGC group
RSK family [OT]
119249909 (RPS6KB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Pkinase_C
Kinase-like
Pkinase_fungal
ABC1
Seadorna_VP7
Motif
Other DBs
NCBI-GeneID:
119249909
NCBI-ProteinID:
XP_037373363
LinkDB
All DBs
Position
Unknown
AA seq
457 aa
AA seq
DB search
MAAVFDLDLETEEGSEGEGEPDFSPSDVCPLAEWRAAGLEAGGHYEEVELTENSVNLGPE
RIGPHCFELLRVLGKGGYGKVFQVRKVQGTNSGKIYAMKVLRKAKIVRNAKDTAHTQAER
NILESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITL
ALGHLHSQGIIYRDLKPENIMLNSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEI
LVRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIKGKLALPPYLTPDARDLI
KKFLKRNPSQRMGGGPGDAADVQRHPFFRHVNWDDLLARRVDPPFRPCLQSEEDVSQFDA
RFTRQTPVDSPDDTALSESANQAFLGFTYVAPSVLDSIKEGFSFQPKLRSPRRLNSSPRT
PIRVAAPLNRGSEGCRLRLPVGVLRPTVPRSGLPLEN
NT seq
1374 nt
NT seq
+upstream
nt +downstream
nt
atggcggcggtgtttgacctggacctggagacggaggaaggcagcgagggagagggcgag
ccagatttcagcccctcggacgtgtgtccccttgccgagtggagggcggctggcctggag
gctgggggacactatgaggaggtggagctgacggaaaacagtgtgaacctgggcccggag
cgcattgggcctcactgctttgagctgctgcgtgtgctgggcaaaggcggctatggcaag
gtgttccaggttcgaaaggtgcagggcaccaactcaggcaagatatatgccatgaaagtg
ctgaggaaggccaaaattgtgcgcaatgccaaggacacagcacacactcaggctgagcgg
aacattcttgagtcagtgaagcatcccttcattgtggaactggcctatgccttccagact
ggtggcaaactctacctcatccttgagtgcctcagtggcggcgagctcttcacacacctg
gagcgagagggcatcttcctggaagacaccgcctgtttctacctggcagagatcacactg
gccctgggccacctccactctcaaggcatcatctaccgggacctcaagcctgagaacatc
atgcttaatagccagggccatatcaagttgactgacttcggactctgcaaggagtccatt
cacgagggcgccgtcacccacaccttctgtggcaccattgagtacatggcccctgagatt
ctggtgcgcagtggccacaacagggcagtggactggtggagcctgggagccctgatgtat
gacatgctcactggatcgcctcccttcactgcagagaaccggaagaaaaccatggacaag
atcatcaaagggaagctggcactgcccccctacctcaccccagatgcccgtgacctcatc
aaaaagtttctgaaacgaaaccccagccaacggatggggggtggcccaggggatgccgcc
gatgtgcagaggcacccctttttccggcacgttaattgggacgacctcctggcccgtcgt
gtggaccccccgttcaggccctgtctgcagtcagaggaagacgtgagccagtttgatgcc
cgcttcacccggcagacgccagtggacagtcccgacgacacggccctgagtgagagcgcc
aaccaggccttcctgggcttcacgtatgtggcgccctccgtcctggacagcatcaaggag
ggcttctctttccagcccaagctgcgctccccgaggcgtctcaacagcagcccgcggacc
cccatcagagtggctgcgcccctgaatcgtggctcggagggctgcaggctccggctgcca
gtgggggtcctgcggcccactgtcccccggtcaggcctgcccttggagaattaa
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