Talpa occidentalis (Iberian mole): 119251590
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Entry
119251590 CDS
T07495
Symbol
NOS3
Name
(RefSeq) nitric oxide synthase, endothelial isoform X1
KO
K13242
nitric-oxide synthase, endothelial [EC:
1.14.13.39
]
Organism
tod
Talpa occidentalis (Iberian mole)
Pathway
tod00220
Arginine biosynthesis
tod00330
Arginine and proline metabolism
tod01100
Metabolic pathways
tod04020
Calcium signaling pathway
tod04022
cGMP-PKG signaling pathway
tod04066
HIF-1 signaling pathway
tod04071
Sphingolipid signaling pathway
tod04151
PI3K-Akt signaling pathway
tod04370
VEGF signaling pathway
tod04371
Apelin signaling pathway
tod04611
Platelet activation
tod04915
Estrogen signaling pathway
tod04921
Oxytocin signaling pathway
tod04926
Relaxin signaling pathway
tod04931
Insulin resistance
tod04933
AGE-RAGE signaling pathway in diabetic complications
tod05415
Diabetic cardiomyopathy
tod05417
Lipid and atherosclerosis
tod05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
tod00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
119251590 (NOS3)
00330 Arginine and proline metabolism
119251590 (NOS3)
09130 Environmental Information Processing
09132 Signal transduction
04370 VEGF signaling pathway
119251590 (NOS3)
04371 Apelin signaling pathway
119251590 (NOS3)
04066 HIF-1 signaling pathway
119251590 (NOS3)
04020 Calcium signaling pathway
119251590 (NOS3)
04071 Sphingolipid signaling pathway
119251590 (NOS3)
04022 cGMP-PKG signaling pathway
119251590 (NOS3)
04151 PI3K-Akt signaling pathway
119251590 (NOS3)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
119251590 (NOS3)
09152 Endocrine system
04915 Estrogen signaling pathway
119251590 (NOS3)
04921 Oxytocin signaling pathway
119251590 (NOS3)
04926 Relaxin signaling pathway
119251590 (NOS3)
09160 Human Diseases
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
119251590 (NOS3)
05418 Fluid shear stress and atherosclerosis
119251590 (NOS3)
05415 Diabetic cardiomyopathy
119251590 (NOS3)
09167 Endocrine and metabolic disease
04931 Insulin resistance
119251590 (NOS3)
04933 AGE-RAGE signaling pathway in diabetic complications
119251590 (NOS3)
Enzymes [BR:
tod01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
119251590 (NOS3)
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Paralog
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Motif
Pfam:
NO_synthase
Flavodoxin_1
Motif
Other DBs
NCBI-GeneID:
119251590
NCBI-ProteinID:
XP_054548727
LinkDB
All DBs
Position
Unknown
AA seq
749 aa
AA seq
DB search
MGNLKSVGQEPGPPCGLGLGLGLGLCSKQGPASPTSEPSRAPAPAPPPMPDYSPPLTRPP
EGPRFPRVKNWEVGSITYDTLSAQSQQDGPCTPKRCLGSLVFPRKPQSRPSRDPPPTEQL
LSQARDFITQYYSSIKRSGSQAHEQRLQEVEAEVAATGTYQLRESELVFGAKQAWRNAPR
CVGRIQWGKLQVFDARDCSSAQEMFTYICNHVKYATNRGNLRSAITVFPQRAPGRGDFRI
WNSQLVRYAGYRQQDGSVQGDPANVEITELCVQHGWTPGNGRFDVLPLLLQAPDEPPELF
ALPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMSTEIG
TRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSYQLAKVTIVDHHAA
TASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYVLSPAFRYQPDPWKGS
AAKGAGITRKKTFKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQLGRLFR
KAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPPENGEGFAAALMEMSGPYSSPRPE
QHRSYKIRFNSISCSDQLVSSWRRKRKESSNTDSAGALGTLRFCVFGLGSRAYPHFCAFA
RAVDTRLEELGGERLLQLGQGDELCGQEEAFRGWAQAAFQVSPCSCPAWPDPGTPPFCLI
PPGPQTCNTEAGASPLSRSCCGLCSLRFF
NT seq
2250 nt
NT seq
+upstream
nt +downstream
nt
atgggcaacttgaagagcgtgggccaggagcctgggcccccctgcggcctggggctgggg
ctgggcctggggctgtgcagcaagcagggcccagcctccccgacctcggagcccagccgg
gcgcctgccccagcgccaccccccatgccagattacagccccccgctcacccgccccccg
gaggggcccaggttcccccgcgtgaagaactgggaggtgggcagcatcacctacgacacc
ctgagcgctcagtcccagcaggatgggccctgcaccccaaaacgctgcctgggatccctg
gtatttcctcggaaaccgcagagccggccctcccgggaccctccaccaacggagcagctg
ctgagccaagccagggacttcatcacccagtattacagctccatcaagaggagcggctcc
caggcccacgagcagcggctgcaggaggtggaggccgaggtggcggccacaggcacctac
cagctccgggagagcgagctggtgttcggggccaagcaggcctggcgcaatgccccgcgc
tgcgtgggccgcatccagtgggggaagctgcaggtgttcgatgcccgggactgcagctct
gcacaggagatgttcacctacatctgcaaccacgtcaagtacgccaccaaccggggcaac
ctccgctcggccatcacagtgttcccccagcgcgctcccggccggggagacttccgaatc
tggaacagccaactggtccgctacgcggggtacaggcagcaggacggctctgtgcaggga
gaccccgccaacgtggagatcactgagctctgcgtgcagcacggctggaccccaggaaac
ggccgcttcgacgtgctgcctctgctgctccaggcccccgatgagcccccggaactgttc
gctctgccccccgagctggtcctcgaggtgcccctggagcaccccacgctagagtggttt
gctgccctgggcctgcgctggtacgcgctccccgccgtgtccaacatgctgctggaaatc
gggggcctggagttccccgcggcccccttcagcggctggtacatgagcaccgagatcggc
acgcggaacctgtgcgacccgcaccgctacaacatcctggaggacgtggccgtctgcatg
gacctggacacccggaccacctcgtccctgtggaaagacaaggcagcggtggaaatcaac
ttggctgtgctgcacagttaccagctggccaaagtgacaattgtggatcaccacgctgcc
acggcctccttcatgaagcacctggagaacgagcagaaggccagggggggctgccctgcc
gactgggcctggatagtgccccccatctcaggcagcctcacccctgtcttccaccaggag
atggtcaactacgtcctctcccctgccttccgctaccagccagacccctggaaggggagc
gcagccaagggcgctggcatcaccaggaagaagacctttaaagaagtggccaatgctgtg
aagatctccgcctcgctcatgggcaccgtgatggcgaagcgcgtgaaggcaaccatcctg
tacggctcggagacgggccgcgcccagagctacgcccagcagctggggaggctcttccgg
aaggccttcgacccccgggtcctgtgcatggatgagtacgacgtggtgtccctcgagcac
gagacgctggtgctggtggtgaccagcacgtttggaaatggagatcccccagagaatgga
gagggcttcgctgctgccctgatggagatgtcgggaccctacagctcccccaggcccgag
cagcacaggagctacaagatccgcttcaacagcatctcctgctcggaccagctggtgtcc
tcgtggcggcggaagagaaaggagtccagtaacacggacagcgctggtgccctgggcacc
ctcaggttctgtgtgttcgggctgggctcccgggcatacccccacttctgcgcctttgca
cgtgcggtggacacccggctggaagagctgggcggggagcggctcctgcagctgggccag
ggggacgagctgtgtggccaggaggaggccttccggggctgggcccaggccgccttccag
gtgagcccctgctcctgccctgcctggcctgacccaggcacccctccattctgcctcatc
cctcctggacctcagacctgcaatactgaggcaggggcctccccgctgtcccgctcttgt
tgcggtctctgctccctccgtttcttctga
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