Talpa occidentalis (Iberian mole): 119252569
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Entry
119252569 CDS
T07495
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
tod
Talpa occidentalis (Iberian mole)
Pathway
tod00270
Cysteine and methionine metabolism
tod00480
Glutathione metabolism
tod01100
Metabolic pathways
tod01240
Biosynthesis of cofactors
tod04216
Ferroptosis
Module
tod_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
tod00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
119252569 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
119252569 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
119252569 (GCLC)
Enzymes [BR:
tod01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
119252569 (GCLC)
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Paralog
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Motif
Pfam:
GCS
GCS2
Motif
Other DBs
NCBI-GeneID:
119252569
NCBI-ProteinID:
XP_037375771
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All DBs
Position
Unknown
AA seq
637 aa
AA seq
DB search
MGLLSQGSPLSWEETQRHADHVRRHGILQFLHIYHAVKDRHKDVLKWGDEVEYMLVSFDH
ENKKVRLVLSGEEVLETLQEKGERTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EDNMRKRRKEATSLLEENQALCTITSFPRLGCPGFTLPEFKPNPVEGGASKSLFFPDEAI
NKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIETFPEHDEAAKASKPDHIYMDA
MGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGVI
SASVDDRTREERGLEPLKNNNYRISKSRYDSIDSYLSKCGENYNDIDLTIDKEIYEQLLQ
EGIDHLLAQHVAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSDI
GWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAVL
RGMFYFRKDICKGGNAVVDGCGPPRNSTELAAEEYTLMSIDTIINGKEGVFPGLIPILNS
YLENMEVDVDTRCSILNYLKLIKKRASGELMTVARWMREFIASHPDYKQDSVITDEMNYS
LIFKCNQIANELCECPELLGPAFRKGKYSESKTDSSN
NT seq
1914 nt
NT seq
+upstream
nt +downstream
nt
atggggctgctgtcccagggctcgccgctcagctgggaggagacccagcgccacgccgac
cacgtgcggcggcacgggatcctccagttcctgcacatctaccacgccgtcaaggaccgg
cacaaggacgtgctcaagtggggcgacgaggtcgaatacatgctggtatcttttgatcat
gaaaataaaaaagtccggttggtcctgtctggagaggaagttcttgaaactctacaagaa
aagggggaacggacaaacccaaaccaccctaccctttggaggccagagtatgggagttac
atgattgaagggacacccggccaaccctatggaggaaccatgtctgagttcaacacagtt
gaagacaatatgagaaaacgtcggaaggaggcgacttctttattagaagaaaatcaggca
ctttgcaccataacttcatttcccagattaggctgtccagggttcacgctgcccgagttc
aagcccaaccccgttgaaggaggagcttccaagtctctcttctttcctgatgaggcaata
aacaagcacccccgcttcagtaccttaacaagaaatatccgacatagaagaggagagaag
gttgtcatcaatgtaccaatatttaaagacaagaatacaccatctccatttatagaaaca
tttcccgagcatgacgaggcagcaaaggcttctaagcctgatcacatttatatggatgcc
atgggtttcgggatgggcaattgctgtctccaggtaacattccaagcctgcagcatatct
gaggccagatacctgtatgatcagttggctactatctgcccaattgttatggctttgagt
gctgcatctcctttttaccgaggctatgtgtcagacattgattgtcgctggggagtgatt
tctgcatctgttgatgatagaactcgagaggagagaggactggagccgctgaagaacaat
aactataggattagtaaatcccgatatgattcaatagacagttatttatctaagtgtggt
gagaattataatgacattgacctaacgattgataaagaaatctatgaacagctgttgcag
gaaggcattgatcatctcctggcccagcatgttgctcatctctttattagagacccgctg
actctgtttgaagagaaaatacaccttgatgatgccaacgagtctgatcattttgagaat
attcagtctacaaattggcagacaatgagattcaagccccctcctccaaactcagatatt
gggtggagagtagaatttcgacccatggaggttcagctaacagattttgagaactctgcg
tatgtggtgtttgtggtgctgcttaccagagtgatcctttcgtacaagttggattttctc
attccactgtcaaaggttgatgaaaacatgaaggtagctcagaaacgagatgctgtcttg
cggggaatgttttatttcaggaaggatatttgcaaaggtggcaacgctgtggtggatggc
tgtggcccaccccggaacagcacggagctggcagcagaagagtacacactgatgagcata
gacaccatcatcaatgggaaggaaggggtgtttcctggactgatcccaatcctgaactcc
tacctggaaaacatggaagtggatgtcgacaccagatgtagtattctgaactacctgaag
ctcattaagaagagagcatcaggagagctaatgacagttgccaggtggatgcgggagttt
atcgcaagccatcctgactacaagcaagacagtgtgataaccgatgaaatgaactatagc
cttattttcaagtgtaaccaaattgcaaatgaattatgtgaatgcccagagttacttgga
ccagcatttaggaaaggaaaatacagtgaaagtaaaactgactcttccaactag
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