Talpa occidentalis (Iberian mole): 119253142 Help Entry 119253142         CDS       T07495                                  Symbol GCK Name (RefSeq) hexokinase-4   KO K12407   glucokinase [EC:2.7.1.2] Organism tod  Talpa occidentalis (Iberian mole) Pathway tod00010   Glycolysis / Gluconeogenesis tod00052   Galactose metabolism tod00500   Starch and sucrose metabolism tod00520   Amino sugar and nucleotide sugar metabolism tod00524   Neomycin, kanamycin and gentamicin biosynthesis tod01100   Metabolic pathways tod01200   Carbon metabolism tod01250   Biosynthesis of nucleotide sugars tod04910   Insulin signaling pathway tod04911   Insulin secretion tod04917   Prolactin signaling pathway tod04922   Glucagon signaling pathway tod04930   Type II diabetes mellitus tod04950   Maturity onset diabetes of the young tod05230   Central carbon metabolism in cancer Module tod_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate tod_M00549   UDP-Glc biosynthesis, Glc => UDP-Glc Brite KEGG Orthology (KO) [BR:tod00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     119253142 (GCK)    00052 Galactose metabolism     119253142 (GCK)    00500 Starch and sucrose metabolism     119253142 (GCK)   09107 Glycan biosynthesis and metabolism    00520 Amino sugar and nucleotide sugar metabolism     119253142 (GCK)   09110 Biosynthesis of other secondary metabolites    00524 Neomycin, kanamycin and gentamicin biosynthesis     119253142 (GCK)  09150 Organismal Systems   09152 Endocrine system    04911 Insulin secretion     119253142 (GCK)    04910 Insulin signaling pathway     119253142 (GCK)    04922 Glucagon signaling pathway     119253142 (GCK)    04917 Prolactin signaling pathway     119253142 (GCK)  09160 Human Diseases   09161 Cancer: overview    05230 Central carbon metabolism in cancer     119253142 (GCK)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     119253142 (GCK)    04950 Maturity onset diabetes of the young     119253142 (GCK) Enzymes [BR:tod01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.2  glucokinase      119253142 (GCK) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Hexokinase_2 Hexokinase_1 Motif Other DBs NCBI-GeneID:  119253142 NCBI-ProteinID:  XP_037376686 LinkDB All DBs Position Unknown AA seq 458 aa AA seqDB search MESAKKEKAEHILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPE GSEVGDFLSLDLGGTNFRVMLVKVGEGEAGQWSVKTKHQMYSIPEDAMTGTAEMLFDYIS ECISDFLDKHQLKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNIVGLLRD AIKRRGDFEMDVVAMVNDTVATMISCYYEDHRCEVGMIVGTGCNACYMEEMQNVELVEGD EGRMCVNTEWGAFGDSGELDEFLLEYDRVVDENSLNPGQQLFEKLIGGKYMGELVRLVLL KLVDENLLFHGEASEQLRTRGAFETRFVSQVESDSGDRKQIYNILSTLGLRPSATDCDIV RRACESVSTRAAHMCAAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASV RRLTPSCEITFIESEEGSGRGAALVSAVACKKACMLGQ NT seq 1377 nt NT seq  +upstreamnt  +downstreamnt atggagagcgccaagaaggaaaaggcggagcacatcctggcagagtttcagctgcaagaa gaagacttgaaaaaggtgatgagacggatgcagaaggaaatggaccgaggcctgagactg gagacccacgaggaggccagtgtgaagatgctgcccacctacgtgcgttccaccccagaa ggctcagaagtcggggactttctctccctggacctgggcggcaccaacttcagggtgatg ctggtgaaggtgggggagggcgaggcgggacagtggagtgtgaaaaccaagcaccagatg tactccatccccgaggacgccatgacgggcacagccgagatgctttttgactacatctcc gagtgcatctctgacttcctggacaagcatcagttgaagcacaagaagctgcccttgggc ttcacattctcctttccagtgagacatgaagacattgacaagggcatccttctcaactgg actaagggcttcaaggcttcgggagcagaagggaacaacattgtggggctcctgcgagat gccatcaaaaggagaggggactttgagatggacgtggtggcaatggtgaatgacactgtg gccacaatgatctcctgctactacgaagaccatcggtgtgaagttggcatgattgtgggc acgggctgtaatgcctgctacatggaggagatgcagaacgtagagctggtggaaggagac gagggccgaatgtgcgtcaacactgagtggggagcctttggagactcaggcgagctggac gagttcctgttggaatatgaccgggtggtggacgagaactccctgaacccaggccagcag ctgtttgagaagctcatcgggggcaagtatatgggcgagctggtgcggctggtgctgctg aagctcgtggatgagaacctgctcttccacggggaggcctcggagcagctgcgaacacga ggtgccttcgagacacgctttgtatcgcaggtggagagtgactcaggagaccggaagcag atctacaacatcctgagcacactgggactgaggccctccgccactgactgtgacatagtg cgccgggcctgtgagagcgtgtccactcgcgccgcgcacatgtgcgccgcaggactggca ggagtcattaaccgcatgcgagagagtcgcagcgaggacgtgatgcgcatcaccgtaggg gtggacggctccgtgtacaagctgcatcccagcttcaaggagcggttccatgccagcgtg cgcaggctgactcccagctgcgaaatcaccttcatcgagtcggaggagggcagtggccgg ggtgcagccctggtctccgcggtggcttgtaagaaggcctgcatgctggggcagtga

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