Talpa occidentalis (Iberian mole): 119257226
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Entry
119257226 CDS
T07495
Symbol
GART
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
tod
Talpa occidentalis (Iberian mole)
Pathway
tod00230
Purine metabolism
tod00670
One carbon pool by folate
tod01100
Metabolic pathways
tod01523
Antifolate resistance
Brite
KEGG Orthology (KO) [BR:
tod00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
119257226 (GART)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
119257226 (GART)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
119257226 (GART)
Enzymes [BR:
tod01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
119257226 (GART)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
119257226 (GART)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
119257226 (GART)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
GARS_N
AIRS_C
GARS_C
AIRS
ATP-grasp
Hexapep
CPSase_L_D2
ATP-grasp_2
Dala_Dala_lig_C
ATP-grasp_4
ATP-grasp_3
Motif
Other DBs
NCBI-GeneID:
119257226
NCBI-ProteinID:
XP_037380907
LinkDB
All DBs
Position
Unknown
AA seq
1054 aa
AA seq
DB search
MTARVLVIGNGGREHTLAWKLAQSYHVKQVLVAPGNAGTAFCEKISNTAVSTSDHTALAQ
FCKDNNIDMVVVGPEAPLAAGIVGNLTSAGVRCFGPTAEAAQLESSKRFAKEFMDRHGIP
TARWKAFTRAEEACRFIMSADFPALVVKASGLAAGKGVIVAKSKEEACKAVQDIMQDKAF
GAAGETVVIEELLEGEEVSCLCFTDGRTVAPMPPAQDHKRLLDGDQGPNTGGMGAYCPAP
QISKDLLLEIKNTILQKTVDGMQQEGVPYTGILYAGIMLTKCGPKVLEFNCRFGDPECQV
ILPLLKSDLYEVIRSTLDGQLYTSPPLWLENRTAVTVVMASKGYPGDYTKGVEITGFSEA
QTLGLEVFQAGTALKDGKVVTSGGRVLTVTAIQENLISALEEAKKGLAAIKFEGAIYRKD
IGYRAIAFLQQPRCLTYKDSGVNIAAGNMLVNRIKPLAKATSRPGCDVSLGDFAGLFDMK
AAGFKNPLLACGTDGVGTKLKIAQQCNRHDTIGQDLVAMCVNDILAQGAEPLIFLDYFAC
GKLDLNIAEAVVKGIAQACQDCQCALLGGETAEMPDMYPPGEYDLAGFAVGAMEREQKLP
QLDRITEGDNVIGIASSGLHSNGFSLVRKIVEKSSLQYSSPAPCGCGDQTLGDLLLTPTR
LYSRSLLPILRLGHVKAFAHITGGGLLENIPRVLPQKFGVDLDAQTWRIPRIFSWLQKEG
HLSEEEMARTFNCGVGAALIVSKDQTKQILRDIEQHKEEAWVIGKVVACPKGSPRVKIKH
LIETIKENGSVLENGTQLGNGTRLGNGTHLGNGTLLENGTSLRNSIQVENGSQLGNGTLK
NHLSLQSEKARVAVLISGTGSNLQALIKSTQEPSSSAHIVVVISNKAAVAGLDKAERAGI
PTRVINHKLYKSREEFDSAIDQVLKEFSTDIVCLAGFMRILSGPFVQKWNGKMLNIHPSL
LPSFKGSNAHEQALDAGVTITGCTVHFVAEDVDAGQIILQEAVQVKRTDTVATLSERVKL
AEHKIFPRALELVASGTVQLGENGKICWVQKGQL
NT seq
3165 nt
NT seq
+upstream
nt +downstream
nt
atgacagcccgagtgcttgtaattggcaatggaggaagagaacatacactggcctggaaa
cttgcacagtcttaccatgtcaagcaagtgttggttgctccaggaaatgcaggcacagcc
ttctgtgaaaagatttcaaatactgctgtttctaccagtgatcacactgcccttgctcaa
ttctgcaaagataacaacattgatatggtggttgttggaccagaagcacctctggctgcg
ggaattgttgggaacctgacatctgcaggggtgcgatgctttggccccacagctgaagca
gctcagttagagtccagcaaaagatttgctaaagagtttatggatcgacatgggatccca
actgcaagatggaaagctttcaccagagctgaagaggcctgccgcttcattatgagtgca
gacttccctgctttggttgtgaaagccagtggtcttgcagctgggaaaggggtgattgtt
gcaaagagcaaagaggaggcctgcaaagcagtgcaggacatcatgcaagataaagctttt
ggagcagctggagaaacagttgtcattgaagaacttcttgaaggagaagaagtatcttgt
ctgtgtttcactgacgggaggaccgtggctccaatgcccccagcccaggaccataagcga
ctgctggacggagaccagggccccaacacaggggggatgggggcctactgtccggcacct
cagatttctaaggatttgttattagagattaaaaataccatacttcagaagacagtggat
ggcatgcagcaggagggtgtgccatacacaggtattctctatgcgggtattatgctgacc
aagtgtggcccgaaggttctagaatttaattgccgttttggtgatccagaatgccaagtg
atcctccctcttcttaaaagtgatctttatgaagtgattcggtccaccttagatggtcag
ctctacacatctccacctctttggcttgaaaaccgcactgcagtaactgttgtcatggca
agtaaaggttaccctggagactacaccaagggtgtggagataacagggttttcagaggct
cagactttaggattggaggtgttccaagcaggcactgccctaaaagatggcaaagtggtt
actagtggagggagagtccttacggtgacagccattcaggaaaatctcatctcagccctt
gaagaagccaagaaaggattagctgctataaagtttgagggagccatttataggaaggac
attggctatcgcgccatagctttcctccagcagcccaggtgcctgacttacaaggactct
ggggtaaacattgcagctggaaatatgttagtcaacaggattaagcctttggcaaaagcc
acctccagaccaggctgtgatgttagtcttggagattttgctggtctttttgacatgaaa
gcagccggtttcaagaatcctcttctggcttgtggaacggatggtgttgggactaaacta
aagattgcccagcagtgcaacagacatgataccattggccaagatttggttgcaatgtgt
gtaaatgatattctggcacaaggagcagagcccctcatcttcctcgattactttgcctgt
ggaaaacttgaccttaatattgccgaagctgttgttaagggaatcgctcaagcttgtcaa
gattgtcaatgtgctctgcttggtggagaaacagcagaaatgcctgatatgtatcctcct
ggagaatatgacttagccggttttgctgtgggtgccatggagcgggagcagaaactccct
cagctggacagaatcactgaaggggacaacgtcattggaatagcttcatctggtcttcac
agcaatggatttagccttgtgaggaaaatcgtagagaaatcttccctgcagtactcctct
ccagcaccttgtggttgtggtgaccagaccttaggggatttacttctgacaccaaccaga
ctctacagccgctcactgttacctatcctgcgcttgggacacgtcaaggcatttgcccat
atcactggtggaggactcctagaaaacattcccagggtcctccctcagaaatttggggta
gatttagatgcccagacctggaggatccccaggatcttttcatggttacagaaggaagga
cacctctctgaagaagagatggccaggacatttaactgtggggttggcgctgccctgata
gtatcaaaggatcagacaaagcaaattctaagggatattgagcagcacaaggaagaagcc
tgggtgattggcaaggtggttgcatgtcctaaaggttctcctcgtgtgaaaatcaagcat
ctgattgaaactataaaagaaaatggatcagtgctggagaatggcacccagctggggaac
ggcacccggctggggaatggtacacatttggggaatggcactctgctagagaatggcacc
tcactacggaacagcatccaggtagagaatggttcccagctggggaacggcaccctgaaa
aatcatttgtctctccagtcagaaaaagcaagagtggctgtcttaatatctggaacagga
tcaaaccttcaagcgctcataaagagtactcaggagccaagtagctctgcacacattgtt
gttgttatctccaacaaagctgcagtggccgggttagataaagcagaaagagctggaatt
cccaccagagtaattaatcataaattgtataaaagtcgtgaagaatttgacagtgcaatt
gaccaagtccttaaagagttctccacagacatagtctgtcttgcaggattcatgagaatc
ttatctggcccctttgtccaaaaatggaatgggaaaatgctcaacatccacccatccttg
ctcccttcttttaagggttcaaatgcccatgaacaggccctggatgccggagtcacaatc
actgggtgcactgtgcactttgtagctgaagacgtagatgctggacagattattttacaa
gaagctgttcaagtgaagaggactgatactgttgcaacactgtctgaaagagtaaaatta
gcagaacataagatctttcccagagctctcgaattggtggccagtggaacggtacagctt
ggagaaaatggcaagatctgttgggtccaaaagggccagctttga
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