Talpa occidentalis (Iberian mole): 119257489
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Entry
119257489 CDS
T07495
Symbol
GSK3B
Name
(RefSeq) glycogen synthase kinase-3 beta isoform X1
KO
K03083
glycogen synthase kinase 3 beta [EC:
2.7.11.26
]
Organism
tod
Talpa occidentalis (Iberian mole)
Pathway
tod01521
EGFR tyrosine kinase inhibitor resistance
tod04012
ErbB signaling pathway
tod04062
Chemokine signaling pathway
tod04110
Cell cycle
tod04150
mTOR signaling pathway
tod04151
PI3K-Akt signaling pathway
tod04310
Wnt signaling pathway
tod04340
Hedgehog signaling pathway
tod04360
Axon guidance
tod04390
Hippo signaling pathway
tod04510
Focal adhesion
tod04550
Signaling pathways regulating pluripotency of stem cells
tod04657
IL-17 signaling pathway
tod04660
T cell receptor signaling pathway
tod04662
B cell receptor signaling pathway
tod04722
Neurotrophin signaling pathway
tod04728
Dopaminergic synapse
tod04910
Insulin signaling pathway
tod04916
Melanogenesis
tod04917
Prolactin signaling pathway
tod04919
Thyroid hormone signaling pathway
tod04931
Insulin resistance
tod04932
Non-alcoholic fatty liver disease
tod04934
Cushing syndrome
tod04935
Growth hormone synthesis, secretion and action
tod04936
Alcoholic liver disease
tod05010
Alzheimer disease
tod05020
Prion disease
tod05022
Pathways of neurodegeneration - multiple diseases
tod05135
Yersinia infection
tod05160
Hepatitis C
tod05162
Measles
tod05163
Human cytomegalovirus infection
tod05165
Human papillomavirus infection
tod05167
Kaposi sarcoma-associated herpesvirus infection
tod05200
Pathways in cancer
tod05210
Colorectal cancer
tod05213
Endometrial cancer
tod05215
Prostate cancer
tod05217
Basal cell carcinoma
tod05224
Breast cancer
tod05225
Hepatocellular carcinoma
tod05226
Gastric cancer
tod05415
Diabetic cardiomyopathy
tod05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
tod00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
119257489 (GSK3B)
04310 Wnt signaling pathway
119257489 (GSK3B)
04340 Hedgehog signaling pathway
119257489 (GSK3B)
04390 Hippo signaling pathway
119257489 (GSK3B)
04151 PI3K-Akt signaling pathway
119257489 (GSK3B)
04150 mTOR signaling pathway
119257489 (GSK3B)
09140 Cellular Processes
09143 Cell growth and death
04110 Cell cycle
119257489 (GSK3B)
09144 Cellular community - eukaryotes
04510 Focal adhesion
119257489 (GSK3B)
04550 Signaling pathways regulating pluripotency of stem cells
119257489 (GSK3B)
09150 Organismal Systems
09151 Immune system
04660 T cell receptor signaling pathway
119257489 (GSK3B)
04657 IL-17 signaling pathway
119257489 (GSK3B)
04662 B cell receptor signaling pathway
119257489 (GSK3B)
04062 Chemokine signaling pathway
119257489 (GSK3B)
09152 Endocrine system
04910 Insulin signaling pathway
119257489 (GSK3B)
04917 Prolactin signaling pathway
119257489 (GSK3B)
04935 Growth hormone synthesis, secretion and action
119257489 (GSK3B)
04919 Thyroid hormone signaling pathway
119257489 (GSK3B)
04916 Melanogenesis
119257489 (GSK3B)
09156 Nervous system
04728 Dopaminergic synapse
119257489 (GSK3B)
04722 Neurotrophin signaling pathway
119257489 (GSK3B)
09158 Development and regeneration
04360 Axon guidance
119257489 (GSK3B)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
119257489 (GSK3B)
09162 Cancer: specific types
05210 Colorectal cancer
119257489 (GSK3B)
05225 Hepatocellular carcinoma
119257489 (GSK3B)
05226 Gastric cancer
119257489 (GSK3B)
05217 Basal cell carcinoma
119257489 (GSK3B)
05215 Prostate cancer
119257489 (GSK3B)
05213 Endometrial cancer
119257489 (GSK3B)
05224 Breast cancer
119257489 (GSK3B)
09172 Infectious disease: viral
05160 Hepatitis C
119257489 (GSK3B)
05162 Measles
119257489 (GSK3B)
05163 Human cytomegalovirus infection
119257489 (GSK3B)
05167 Kaposi sarcoma-associated herpesvirus infection
119257489 (GSK3B)
05165 Human papillomavirus infection
119257489 (GSK3B)
09171 Infectious disease: bacterial
05135 Yersinia infection
119257489 (GSK3B)
09164 Neurodegenerative disease
05010 Alzheimer disease
119257489 (GSK3B)
05020 Prion disease
119257489 (GSK3B)
05022 Pathways of neurodegeneration - multiple diseases
119257489 (GSK3B)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
119257489 (GSK3B)
05415 Diabetic cardiomyopathy
119257489 (GSK3B)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
119257489 (GSK3B)
04932 Non-alcoholic fatty liver disease
119257489 (GSK3B)
04931 Insulin resistance
119257489 (GSK3B)
04934 Cushing syndrome
119257489 (GSK3B)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
119257489 (GSK3B)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
tod01001
]
119257489 (GSK3B)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
tod03036
]
119257489 (GSK3B)
Enzymes [BR:
tod01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.26 tau-protein kinase
119257489 (GSK3B)
Protein kinases [BR:
tod01001
]
Serine/threonine kinases: CMGC group
GSK family [OT]
119257489 (GSK3B)
Chromosome and associated proteins [BR:
tod03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
119257489 (GSK3B)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
ABC1
Kinase-like
Kdo
APH
Motif
Other DBs
NCBI-GeneID:
119257489
NCBI-ProteinID:
XP_037381385
LinkDB
All DBs
Position
Unknown
AA seq
433 aa
AA seq
DB search
MSGRPRTTSFAESCKPVQQPSAFGSMKVSRDKDGSKVTTVVATPGQGPDRPQEVSYTDTK
VIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSG
EKKDEVYLNLVLDYVPETVYRVARQYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHR
DIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDV
WSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHP
WTKDSSGTGHFTSGVRVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPN
VKLPNGRDTPALFNFTTQELSSNPPLATILIPPHARIQAAASTPTNATAASDANAGDRGQ
TNNAASASASNST
NT seq
1302 nt
NT seq
+upstream
nt +downstream
nt
atgtcagggcggcccagaaccacctcctttgcggagagctgcaagccggtgcagcagccc
tcggcttttggcagcatgaaagttagcagagataaggatggcagcaaggtgaccacagtg
gtggcaactcctgggcagggtccagacaggccacaagaagtcagctatacagacactaaa
gtaattggaaatgggtcatttggtgtggtatatcaggccaaactttgtgattcaggagaa
ctggttgccatcaagaaagtattgcaggacaagagatttaagaaccgtgaacttcagatc
atgagaaagctagatcactgtaacatagtccgattgcgctacttcttctactcaagtggt
gagaagaaagatgaggtctatcttaatctggtgctggactatgttccggaaacagtatac
agagttgccagacagtatagtcgagccaaacagacgctccctgtgatctatgtcaagttg
tatatgtatcagctatttcgaagtttagcctatatccattcctttggaatctgccatcgg
gatattaaaccacagaacctcttgttggatcctgatacagctgtcttaaaactctgtgac
tttggaagcgcaaagcagctggtccgaggagaacccaatgtttcgtatatctgttctcgg
tactatagggcaccagagttgatctttggagccactgattatacctctagtatagatgta
tggtctgcaggctgtgtgttggctgagctgttgctaggacaaccaatatttccaggggac
agtggtgtggatcaattggtggaaattatcaaggtcctgggcacaccaacaagggagcaa
attcgagaaatgaacccaaactacacagaattcaaattccctcaaataaaggcacatcct
tggactaaggattcgtcaggaacaggacatttcacctcaggagtgcgggtcttcagaccc
cgaactccaccagaagcaattgcactgtgtagccgtctcctggaatatacaccaactgcc
cgattgacaccactggaagcttgtgcacattcattttttgatgaattacgggacccaaat
gtcaaactacctaatggacgagacacacctgcactcttcaacttcaccactcaagaactg
tcaagtaatccacctctagctaccatccttattcctcctcatgcgaggattcaagcagct
gcttcaacccctacaaatgccacagcagcctcagatgctaatgccggagaccgtggacag
accaataatgccgcttctgcatcagcttccaactccacctga
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