Talpa occidentalis (Iberian mole): 119260571
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Entry
119260571 CDS
T07495
Symbol
PDE8B
Name
(RefSeq) LOW QUALITY PROTEIN: high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
tod
Talpa occidentalis (Iberian mole)
Pathway
tod00230
Purine metabolism
tod01100
Metabolic pathways
tod04927
Cortisol synthesis and secretion
tod04934
Cushing syndrome
tod05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
tod00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
119260571 (PDE8B)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
119260571 (PDE8B)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
119260571 (PDE8B)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
119260571 (PDE8B)
Enzymes [BR:
tod01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
119260571 (PDE8B)
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Ortholog
Paralog
GFIT
Motif
Pfam:
PDEase_I
PDE8A_N
PDE8
PAS_9
PAS
PAS_3
PAS_4
PAS_8
DUF4194
DHH
Motif
Other DBs
NCBI-GeneID:
119260571
NCBI-ProteinID:
XP_037385439
LinkDB
All DBs
Position
Unknown
AA seq
884 aa
AA seq
DB search
MGCAPSIHVSQSGVIYCRDSDESNSPRQTTGASPGPAAALHGLFVQTDAADAXPPSRASG
PPGAARVRRARGELGSGSSAGSAARAATTCRGRRRHCCSSAEAETQTSYTSVKVSSAEVR
IGPMRLTQDPIQVLLIFAKEDSQSDGFWWACDRAGYRCNIARTPESALECFLDKHHEIIV
IDHRQTRNFDAEAVCRSIRATNPSEHTVILAVVSQALGDHEEASVLPLLHAGFNRRFMEN
SSIIACYNELIQIEHGEVRSQFKLRACNSVFTALDHCHEAIEITSDDHVIQYVNPAFERM
MGYHKGELLGKELAELPKSDKNRADLLDTINTCIKKGKEWQGVYYARRKSGDSIQQHVKI
TPVIGQGGKIRHFVSLKKLCCTTDNNKQLHKVHRDSGDNSQTESHSFRYKNRRKESIDVK
SISSRGSDAPSLQNRRYPSMARIHSMTIEAPITKVINIINAAQENSPVTVAEALDRVLEI
LRTTELYSPQLGTKDEDPHTSDLVGGLMTDGLRRLSGNEYVFTKNVHQSHSHLAMPITIN
DVPPSIAQLLDNEESWEFNIFELEAVTHKRPLVYLGLKVFSRFGVCEFLHCSETTLRAWL
QVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVHDVDHPG
RTNSFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKDSKCNIFKNIDRNHYRTLRQAII
DMVLATEMTKHFEHVNKFVNSINKPLAAEVEGSDCECNPVGKNFPENQILIKRMMIKCAD
VANPCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMPVFDRNTCSIPKSQISFIDYFI
TDMFDAWDAFAHLPALMQHLADNYKHWKTLDDLKCKSLRLPSDS
NT seq
2655 nt
NT seq
+upstream
nt +downstream
nt
atgggctgcgcccctagcatccacgtctcgcagagcggcgtgatctactgccgggactcg
gacgagtccaactcgccccgccagaccaccggcgcgtctccgggccccgcggccgccctg
cacggcctcttcgtccagaccgacgccgccgacgccnatccccccagccgcgcgtccgga
cccccgggcgccgcccgcgtccgcagggcccgaggcgagctgggcagcggcagcagcgcg
ggctccgctgcccgcgcggcgaccacctgcaggggccggaggcgccactgctgcagcagc
gcggaggccgagacccagaccagctacaccagcgtcaaggtttcttctgcggaggtgcgc
attgggcccatgagactgacgcaggaccctatccaggttttgctgatctttgcaaaggaa
gacagtcagagcgatggattttggtgggcctgtgacagagccggttatagatgcaatatt
gcacggactccagagtcagcccttgaatgctttctagataaacatcatgaaattattgta
atagatcacagacaaactcgaaactttgatgcagaagcagtgtgcaggtctatccgggct
acaaacccctccgagcacacagtgatccttgcggtggtttcacaagcattgggcgaccat
gaagaggcctcagtcctccctcttctgcatgcaggcttcaacaggagatttatggagaat
agcagcataattgcttgctataatgaattgattcaaatagaacatggggaagttcgctca
cagttcaaattacgggcctgtaattcagtgtttactgcattagaccattgtcatgaagcc
atagagataacaagcgatgaccatgtgattcagtacgtcaacccagcctttgaaaggatg
atgggctaccacaagggcgagcttctggggaaggaactggccgaactacccaagagcgat
aagaaccgagcagacctcctggacaccatcaacacatgcatcaagaagggcaaggagtgg
cagggggtttactatgccagacggaaatccggggacagcatccaacagcacgtgaagatc
accccggtgattggccaaggagggaaaattaggcattttgtctccctcaagaaactgtgt
tgtaccactgacaataataagcagcttcacaaagttcatcgtgattcaggggacaattct
cagacagagtctcattcattcagatacaagaacaggaggaaagagtctattgatgtgaaa
tcgatatcttctcgtggcagtgatgcccccagcctgcagaatcggcgctacccgtccatg
gcaaggatccattccatgaccatcgaggcgcccatcacaaaggtcataaatataatcaat
gctgcccaagaaaacagccccgtcacagtagcagaagccttggatagagttttagaaatt
ctgcggaccacggaactgtactcccctcagctgggtaccaaggatgaagatcctcacacc
agtgaccttgtcggcggcctgatgacggatggcttgaggaggttgtcaggaaacgagtat
gtattcactaaaaatgtgcaccagagtcacagtcaccttgcgatgccaataaccatcaac
gacgtccccccgagtatcgctcaattgctcgataatgaggaaagctgggagttcaacatc
tttgagttggaagctgtgacacataaaaggccgttggtttatctgggcttaaaggtcttt
tcccggtttggagtatgtgaatttttacactgctctgaaactactctccgggcctggctc
caagtgatcgaagccaactatcactcctccaatgcttatcataactccacccacgccgcc
gacgttctgcatgccactgccttcttcctcggaaaggaaagagtaaagggaagcctcgat
cagctggatgaggtggcagcattgattgctgccacggtccacgatgtggatcacccggga
aggaccaactcgttcctgtgcaatgcaggcagtgagctcgccgtgctctataacgacacc
gctgtcctggagagtcaccacacagccctggccttccagctcacagtcaaagacagcaaa
tgcaacattttcaagaatattgacaggaaccattatcgaacgctgcgccaggctattatt
gacatggttttagcaacggagatgacaaaacactttgaacatgtgaacaaatttgtgaac
agcatcaataagccactggcagctgaggttgagggcagcgactgtgaatgcaaccctgtt
ggaaagaacttccctgaaaatcaaatcctgatcaagcgcatgatgattaagtgtgctgat
gtggccaatccatgccgccctctggacctgtgcattgagtgggctgggaggatctccgag
gagtattttgcacagactgatgaagaaaagagacaggggctccccgtggtgatgccagtg
ttcgaccggaatacctgcagcatccccaagtcccagatctccttcattgactacttcatc
acggacatgtttgatgcttgggatgcctttgcacatctgccagccttgatgcaacactta
gcagataactacaaacactggaagacattagatgacctaaagtgcaaaagtctgaggctt
ccatctgacagctaa
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