Talpa occidentalis (Iberian mole): 119260801
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Entry
119260801 CDS
T07495
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial-like
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
tod
Talpa occidentalis (Iberian mole)
Pathway
tod00010
Glycolysis / Gluconeogenesis
tod00020
Citrate cycle (TCA cycle)
tod00620
Pyruvate metabolism
tod00785
Lipoic acid metabolism
tod01100
Metabolic pathways
tod01200
Carbon metabolism
tod01210
2-Oxocarboxylic acid metabolism
tod04066
HIF-1 signaling pathway
tod04922
Glucagon signaling pathway
tod05230
Central carbon metabolism in cancer
tod05415
Diabetic cardiomyopathy
Module
tod_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
tod00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
119260801
00020 Citrate cycle (TCA cycle)
119260801
00620 Pyruvate metabolism
119260801
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
119260801
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
119260801
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
119260801
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
119260801
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
119260801
Enzymes [BR:
tod01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
119260801
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Paralog
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
119260801
NCBI-ProteinID:
XP_037385778
LinkDB
All DBs
Position
Unknown
AA seq
391 aa
AA seq
DB search
MRKTLAAAVFRVLSGVSQKPPSRVLVASCNFSNDATFEIKKCELHRLEEGPPVTTVLTRE
DGLKYYKMMQSIRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPTDHVITSYR
AHGLCYVRGISARGILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQGPLGVGIAL
ACKYKGTNEVCLTLYGDGAANQGQIAEAHNMAALWKLPCIFICENNFYGMGTSVERAAAN
TEYYKRGNCIPGLRVDGMDVLCVREATKFAVDFCRSGKGPILMELQTYRYHGHSMSDPGI
SYRTREEIQNVREKRDPIMLLKNRMVNNNLASVEELKEIDVSVRKEIDDAAQFAITDPEP
NLEELGHHIYSSNTPFLVRGTNQWIQFKSLS
NT seq
1176 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagacgcttgctgccgctgtcttccgcgtgctatcgggtgtctcccagaagccg
cctagcagagtgctagtagcttcctgtaacttctccaatgatgctacatttgaaattaag
aaatgtgagcttcatcggttggaagagggtccccctgtcacaaccgtgttaaccagggag
gatgggctcaagtactacaagatgatgcagagcattcgtcgaatggaattgaaggcagat
cagctgtataaacaaaaatttattcgtggtttctgtcacttgtgtgatggtcaggaagct
tgttgcgtgggccttgaggctgggataaatccaacagatcatgtcatcacatcctatcgg
gctcatggtttgtgctatgtgcgtggaatttctgctcgaggaattcttgccgaattgaca
ggaagaagaggaggttgtgctaaaggtaaaggtggctcaatgcatatgtatgccaagaat
ttctatgggggtaatggcattgttggtgctcaaggacccctgggagttggtattgcactg
gcctgtaaatataagggaaccaatgaggtctgtttgactctgtacggggatggtgctgct
aatcaggggcagatagctgaagctcacaatatggcagctttgtggaaattaccttgcatt
ttcatctgtgagaataacttctatggaatggggacatctgttgagagagcagcagccaac
actgaatactacaagagaggaaattgtatccctggattaagagtggatggaatggatgtt
ctgtgcgttcgggaagcaactaagtttgcagttgatttttgcagatctggaaaggggccc
atactaatggagctgcaaacataccgttaccatggacacagtatgagtgatcctggaatc
agttaccgaacacgagaagaaattcagaatgtaagagagaagcgtgatcctattatgctt
ctcaaaaatagaatggtaaacaacaaccttgccagtgttgaagaactgaaagaaattgat
gttagtgtgcggaaagaaattgatgatgcagcccagtttgctataactgatcctgaacca
aatttggaagagctaggccatcatatctacagcagtaatacaccttttctagttcgtggc
acaaatcaatggatccaatttaagtctctcagttaa
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