Talpa occidentalis (Iberian mole): 119261223
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Entry
119261223 CDS
T07495
Symbol
PDGFRA
Name
(RefSeq) platelet-derived growth factor receptor alpha
KO
K04363
platelet-derived growth factor receptor alpha [EC:
2.7.10.1
]
Organism
tod
Talpa occidentalis (Iberian mole)
Pathway
tod01521
EGFR tyrosine kinase inhibitor resistance
tod04010
MAPK signaling pathway
tod04014
Ras signaling pathway
tod04015
Rap1 signaling pathway
tod04020
Calcium signaling pathway
tod04072
Phospholipase D signaling pathway
tod04144
Endocytosis
tod04151
PI3K-Akt signaling pathway
tod04510
Focal adhesion
tod04540
Gap junction
tod04630
JAK-STAT signaling pathway
tod04810
Regulation of actin cytoskeleton
tod05163
Human cytomegalovirus infection
tod05200
Pathways in cancer
tod05206
MicroRNAs in cancer
tod05214
Glioma
tod05215
Prostate cancer
tod05218
Melanoma
tod05230
Central carbon metabolism in cancer
tod05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
tod00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
119261223 (PDGFRA)
04014 Ras signaling pathway
119261223 (PDGFRA)
04015 Rap1 signaling pathway
119261223 (PDGFRA)
04630 JAK-STAT signaling pathway
119261223 (PDGFRA)
04020 Calcium signaling pathway
119261223 (PDGFRA)
04072 Phospholipase D signaling pathway
119261223 (PDGFRA)
04151 PI3K-Akt signaling pathway
119261223 (PDGFRA)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
119261223 (PDGFRA)
09144 Cellular community - eukaryotes
04510 Focal adhesion
119261223 (PDGFRA)
04540 Gap junction
119261223 (PDGFRA)
09142 Cell motility
04810 Regulation of actin cytoskeleton
119261223 (PDGFRA)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
119261223 (PDGFRA)
05206 MicroRNAs in cancer
119261223 (PDGFRA)
05230 Central carbon metabolism in cancer
119261223 (PDGFRA)
05231 Choline metabolism in cancer
119261223 (PDGFRA)
09162 Cancer: specific types
05214 Glioma
119261223 (PDGFRA)
05218 Melanoma
119261223 (PDGFRA)
05215 Prostate cancer
119261223 (PDGFRA)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
119261223 (PDGFRA)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
119261223 (PDGFRA)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
tod01001
]
119261223 (PDGFRA)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
tod04090
]
119261223 (PDGFRA)
Enzymes [BR:
tod01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
119261223 (PDGFRA)
Protein kinases [BR:
tod01001
]
Receptor tyrosine kinases (RTK)
PDGFR family [OT]
119261223 (PDGFRA)
CD molecules [BR:
tod04090
]
Proteins
119261223 (PDGFRA)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Ig_3
I-set
ig
Ig_2
VEGFR1-3_N_Ig-like
VEGFR-1-like_Ig-like
V-set
Herpes_gE
C2-set_2
DUF3475
Kinase-like
Motif
Other DBs
NCBI-GeneID:
119261223
NCBI-ProteinID:
XP_037386366
LinkDB
All DBs
Position
Unknown
AA seq
1091 aa
AA seq
DB search
MGTSHWAFLVLGCLLAGPSLILCQLSFPSILPNENEKVVQLNSSFSLRCFGESEVSWQYP
MSEEENPNVEIRNEENNSGLFVTVLEVVGASAAHTGLYTCYYNHTQAEESEIEGRSIYIY
VPDPDIAFVPLGMTDYLVIVEDDDSAIIPCRTTDPETPVTLLNSDGEVQASASYDSRQGF
NGTFTVGSYTCEATVKGRKFKTIAFNVYALKATSNLDLKMEALKTVYKSGETVEVTCAVF
NNEVVDLQWTYPGEVKGKGITKLEEIKVPSITLVYTLKVPDATVKDSGDYECAARQATKE
VKEMKKVTISVHEKGFIEIEPNFSQLETVNLHEVKHFVVDVQAYPPPRISWLKDNLTLIE
NLTEITTDVEKIQEIRYRSKLKLIRAKEEDSGHYTIVVQNEDDVKSYTFELLTQVPSSIL
DLVDDHHGSTGGQTVRCTAEGTPLPEIEWMICKDIKKCNNETSWTILANNISNIITEFHP
RDRSTVEGQVTFAKVEETIAVRCLAKNLLGAENRELKLVAPTLRSELTVAAAVLVLLVIV
IISLIVLVVIWKQKPRYEIRWRVIESISPDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRI
LGSGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMTHLGPHLNIV
NLLGACTKSGPIYIITEYCFYGDLVNYLHKNRDSFLSHHPEKPKKDLDIFGLNPTDESTR
SYVILSFENNGDYMDMKQADTTQYVPMLERKEVSKYSDIQRSLYDRPASYKKKSMLESEV
KNLLSDDNSEGLTLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFG
LARDIMHDSNYVSKGSTFLPVKWMAPESIFDNLYTTLSDVWSYGILLWEIFSLGGTPYPG
MMVDSTFYNKIKSGYRMAKPDHATSEVYEIMVKCWNSEPEKRPSFYHLSEIVENLLPGQY
KKSYEKIHLDFLKSDHPAVARMRVDPDNAYIGVTYKNEEDKLKDWEGGLDEQRLSADSGY
IIPLPDIDPVPEEEDLGKRNRHSSQTSEESAIETGSSSSTFIKREDETIEDIDMMDDIGI
DSSDLVEDSFL
NT seq
3276 nt
NT seq
+upstream
nt +downstream
nt
atggggacttcccattgggcattcctggtcctaggctgtctcctcgcaggaccgagccta
atcctctgccagctttcattcccctctatccttccaaacgaaaatgaaaaggttgtgcag
ctgaattcatccttttctctgagatgctttggggagagtgaagtgagctggcagtacccc
atgtctgaagaagagaaccccaatgtggaaatcagaaatgaagaaaacaacagtggcctt
tttgtgacagtgttggaggtggtcggcgcctcggcggcccacacgggactgtacacttgc
tattacaaccacacgcaggcagaggaaagcgagattgaaggcagaagcatctatatctac
gtgccagacccagatatagccttcgtccctctaggaatgacagattatttagtcatcgtg
gaggacgatgactctgccatcataccttgtcgcacgactgaccccgagactccggtcacc
ttgctcaacagcgacggagaggtgcaggcctccgcctcctacgacagcagacagggcttt
aatggcacatttaccgttgggtcctatacctgtgaggccactgtcaaagggaggaagttc
aagaccatcgcgttcaatgtttacgctttaaaagcaacatcaaaccttgatctgaaaatg
gaagctcttaaaactgtctataagtcaggggaaacagttgaggtcacctgtgcagtcttt
aacaatgaggtggtggaccttcagtggacttaccctggagaagtgaaaggcaaaggcatc
acaaagctggaggaaatcaaagtcccgtccatcacattggtgtatactctgaaggtcccc
gatgccacggtgaaagatagtggagattatgaatgtgctgcccgccaggccaccaaggag
gtgaaagagatgaagaaggtcaccatttctgtccatgagaaagggttcattgaaatcgaa
cctaacttcagtcagttggaaactgtcaacctgcatgaagtcaagcactttgtggtagat
gtgcaggcctaccctcctccccggatatcctggttgaaggacaatctgactctgatcgag
aacctcaccgagatcaccactgacgtagaaaagattcaggaaataaggtatcgaagcaaa
ttaaagctgatccgagctaaggaggaagacagtggccattatactattgtagttcaaaat
gaagatgatgtgaaaagctatacttttgaactcttaactcaagttccctcatctattctg
gacttggtcgatgaccaccatggctctaccgggggacagacggtgaggtgcacagccgaa
gggacaccccttcctgagatcgagtggatgatctgcaaggatattaagaaatgtaataat
gaaacttcatggacgattttggccaacaacatctcaaacatcatcacggagttccacccc
cgagacaggagtaccgtggaaggccaagtgacgttcgccaaggtggaggagaccatcgca
gtgcgatgcttggctaagaatctcctgggggctgagaaccgagaactgaagctggtggcg
cccactctgcgttctgaactcacggtggcggctgctgtcctggtgttgttggtgattgtg
atcatctcacttattgtcctggttgtcatttggaaacagaaaccaaggtatgaaattcgt
tggagggtcattgaatcaatcagccctgatggacatgaatatatttatgtggacccgatg
cagttgccttatgactcaagatgggagtttccaagagatggactagtgcttggtcgtatc
ctgggatccggtgcatttggaaaagtggttgaaggaactgcctatggattaagccgctcc
cagcccgtcatgaaagtagcagtgaagatgctaaaacccacagccagatccagtgaaaag
caagctctcatgtctgaactgaagataatgactcacctggggccgcatttaaacattgta
aacttgctgggagcctgtaccaagtcaggtcccatttacattatcactgagtactgcttc
tatggggatttggtcaattatttgcataagaatagggacagtttcctgagccaccaccca
gagaagccaaagaaagacctggacatctttgggttgaaccccacagatgaaagcacacgg
agctatgttattttatcttttgaaaacaacggtgactacatggacatgaagcaagctgat
accacacagtatgtgcccatgctggaaaggaaagaggtttctaaatactcagacatccag
agatccctgtatgatcgcccagcctcatacaagaagaagtcgatgttagaatcagaagtc
aaaaaccttctttctgatgataactcagaaggccttaccttgttggatttgttgagcttt
acttaccaagttgcccgtggaatggagtttttggcttcaaaaaattgtgtccaccgggac
ctggctgctcgcaacgtcctcctggcgcaagggaaaatagtgaaaatctgtgactttggc
cttgcaagagacatcatgcacgattcgaactacgtgtccaaaggcagcacatttctccct
gtgaagtggatggctcctgagagcatcttcgacaacctctataccacactgagcgacgtc
tggtcttatggcattctgctctgggagatcttttcccttggtggcaccccctaccctgga
atgatggtggattctactttctataataagatcaagagtgggtaccggatggccaagcct
gaccatgccaccagtgaagtctacgagatcatggtgaaatgctggaatagtgagccagag
aagagaccctccttttaccacctgagtgagattgtggagaatctgctgcctggacaatat
aaaaagagttatgaaaagattcacctggacttcctgaagagcgaccatccggctgtggca
cgcatgcgcgtggaccccgacaatgcctacattggtgtcacctacaaaaacgaggaagac
aagctgaaggattgggagggtggcctggatgagcagaggctgagcgcggacagtggctac
atcatccctctgcctgacatcgatcctgtgcccgaggaggaagacctgggcaagaggaac
cgacacagctcgcagacctctgaagagagtgccattgagacaggttctagcagctcaact
ttcattaagagagaggatgagaccattgaggacatcgacatgatggatgacattggcata
gactcctcagacctggtggaggacagcttcctgtaa
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integrated database retrieval system
