Thermodesulfobacterium geofontis: TOPB45_0723
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Entry
TOPB45_0723 CDS
T01547
Name
(GenBank) 2-isopropylmalate synthase/homocitrate synthase family protein
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
top
Thermodesulfobacterium geofontis
Pathway
top00290
Valine, leucine and isoleucine biosynthesis
top00620
Pyruvate metabolism
top01100
Metabolic pathways
top01110
Biosynthesis of secondary metabolites
top01210
2-Oxocarboxylic acid metabolism
top01230
Biosynthesis of amino acids
Module
top_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
top00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
TOPB45_0723
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
TOPB45_0723
Enzymes [BR:
top01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
TOPB45_0723
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
PEP_mutase
Motif
Other DBs
NCBI-ProteinID:
AEH22825
UniProt:
F8C558
LinkDB
All DBs
Position
complement(720951..722543)
Genome browser
AA seq
530 aa
AA seq
DB search
MAKRKVEIYDTTLRDGAQAEEVNFSLEDKIRIALKLDEFKIDYIEGGWPGSNPKDLQFFK
EIRNYNLKHAKIVAFGSTHHPKKNPETDENLKQLLLAKTPVVTIFGKSWTVHVKDALKVD
LETNLEIISNSIRFLKANVKKVFYDAEHFFDGFKEDPDYAIETIKRAKSAGADCIILCDT
NGGTLPFEMVEIIKEVKRRLGRGFNFGIHAHNDSECAVVNSLEAVRLGAVQVQGTINGIG
ERCGNANLCSIIPNLVLKMGYHCSCAENLHKLTEVSKYVFEIANLPHPSRLPFVGRSAFA
HKGGVHVSAVLKSPRTYEHIDPLAVGNVRRVLVSELSGKSNIIYKAREFGIDLKMDSPLL
NKIVEEIKNLEAEGYEFEAAEASLELLIYRLMGEPKQYFELLSYKVFDLKIDQHFPKAEA
TVLVRVPPGVGEVEHTAALGNGPVNALDNALRKALERFYPQIKEMELEDYKVRVLPGLPG
TASKVRVLIISRSKDKKWGTVGVSTDILEASCQALIDSYTYKLFLDKKGN
NT seq
1593 nt
NT seq
+upstream
nt +downstream
nt
atggctaaaagaaaagtagaaatttacgatactactttaagagatggagcacaagcagaa
gaagttaatttttccttagaagataaaataagaattgctttaaaattagatgaatttaag
atagattatattgaaggggggtggcctggttcaaacccaaaggatttacaattttttaaa
gaaattagaaattataatttaaagcatgcaaaaattgttgcttttggaagcacccatcat
cctaaaaaaaatccagaaacagacgaaaatttaaaacaacttctacttgctaaaacacct
gtagttactatctttgggaaatcttggactgttcatgtaaaagatgctctaaaagttgat
ttagaaaccaatttagaaattatttcaaattcaataaggtttttaaaagcaaatgttaaa
aaggttttttatgatgcagaacacttttttgatggatttaaagaagatccagattatgct
atagaaaccataaaaagagcaaaatctgctggtgcagactgtattatcctttgtgacact
aatggaggaactcttccttttgagatggtagaaattataaaagaagttaagaggagatta
ggaaggggttttaattttggaatccatgctcataatgattcagaatgtgcagtagtaaat
agtttagaagctgttagattaggtgctgtccaggttcagggaaccataaatggtattggt
gaaagatgtggaaatgcgaatctttgttctattattccgaatcttgttttaaaaatggga
tatcattgtagttgtgcagaaaatttacataaattaactgaggtttctaaatatgttttt
gagatagcaaatcttcctcatccttcacgtcttccttttgtaggaagatcagcttttgct
cataaaggtggagtccatgtatctgcagttcttaaatcaccaagaacttacgaacatata
gatcctttagcagtaggcaatgtaagaagagttttagtttcagaactttcagggaaaagc
aatatcatttataaagcaagagaatttgggattgatcttaaaatggacagtcctctttta
aacaaaatagttgaagagatcaaaaacttagaggctgaaggatatgaatttgaagctgct
gaggcatccttagaacttctcatttatagattgatgggagaaccaaaacaatattttgaa
cttttaagctataaagtttttgatttaaaaatagatcaacactttccaaaagcagaggca
acagttttagtaagagttcctccaggagtaggagaagttgaacatactgctgctttagga
aacggacctgttaatgcccttgataatgctttgagaaaagctttagaaagattttatcct
caaataaaagaaatggaattagaagattataaagtaagagttttacctggtcttccagga
actgcttctaaagtaagggttcttattatctccagaagtaaagacaaaaaatggggaaca
gtaggtgtatctacagatattcttgaagcaagctgtcaagctttaatagattcttatact
tataaactttttcttgacaaaaagggaaactaa
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