Thermus oshimai: Theos_1227
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Entry
Theos_1227 CDS
T02346
Name
(GenBank) 2-isopropylmalate synthase/homocitrate synthase family protein
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
tos
Thermus oshimai
Pathway
tos00290
Valine, leucine and isoleucine biosynthesis
tos00620
Pyruvate metabolism
tos01100
Metabolic pathways
tos01110
Biosynthesis of secondary metabolites
tos01210
2-Oxocarboxylic acid metabolism
tos01230
Biosynthesis of amino acids
Module
tos_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
tos00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
Theos_1227
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Theos_1227
Enzymes [BR:
tos01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
Theos_1227
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GFIT
Motif
Pfam:
HMGL-like
HCS_D2
LeuA_dimer
TMP-TENI
Motif
Other DBs
NCBI-ProteinID:
AFV76268
UniProt:
K7QX64
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All DBs
Position
complement(1174937..1176526)
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AA seq
529 aa
AA seq
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MVEILDTTLRDGTQGEGVSLSVDDKVAIARRLAAFGVHLIEGGWPGSNPKDAEFFARMKG
VDLGEARLAAFGATRRKGLLPEEDPSVLALLEAETPVVVLFGKSWTLHVLEALETTLEEN
LAMIRDTVAFFAKRGRRVVYDAEHFFDGYKEDPGYALATLEAALEGGADTLVLCDTNGGS
LPEEVYAITKTVVERFPGVRIGIHPHNDAELAVANALAAVRAGATHAQGTINGYGERCGN
LNLTSFLPTLVFKYGIPAIPPERLRGLKELAHFVDERANLTPNRRAPYVGEAAFAHKAGV
HVSAVLKNPRTYEHIPPEWVGNSRRFLVSDVSGRSNLLAKLQEVGVDLSKEEAKRLLEEV
KALEYEGYAFEGAEASFYLLAHRMKGGGLPFQVEGFSVFVHGSGLSTAWAEATVRVRVGE
SLEHTAAESPYGPVSALDRAFRKAILGFYPELADVELADYKVRILSGQEAGTNSGVRVLV
EMRRGEERFATVGASENILEASLKALTDGYAYALLKPLLERALTGSRGG
NT seq
1590 nt
NT seq
+upstream
nt +downstream
nt
atggtggagatcctagacaccaccttacgggacgggacccaaggggagggggtgagcctc
tccgtggacgacaaggtggccatcgccaggaggcttgccgccttcggcgtccacttgatt
gaggggggctggcccggctccaaccccaaggacgcggagttcttcgcccgcatgaagggg
gtggacctgggggaagcccggcttgccgccttcggggccacccgcagaaaaggcctcctc
cccgaggaggacccttccgtcctggcccttctggaggcggagaccccggtggtggtcctc
ttcggcaagagctggaccctgcacgtcctcgaggccctggagaccaccctggaggagaac
ctggccatgatccgggacaccgtggccttctttgctaagaggggccggcgggtggtgtac
gacgcggagcacttctttgacgggtacaaggaggaccctggctacgccctcgccactctg
gaggcggccctggaggggggtgcggacaccctggtcctctgcgacaccaacgggggctcc
ctccccgaggaggtctacgccatcaccaagaccgtggtggagcgcttccccggggtgagg
atcggcatccacccccataacgacgcggagctcgccgtggccaacgccctggccgcggtc
cgggccggggccacccacgcccagggcaccattaacggctacggggagcggtgcggcaac
ctgaacctcacctccttcctccccaccctggtcttcaagtacggcatccccgccatccct
ccggaaaggcttcgggggctcaaggagctcgcccacttcgtggacgaacgggccaacctc
accccgaaccgccgggccccctacgtgggggaggcggccttcgctcacaaggcgggggtg
cacgtctccgccgtgctcaagaacccccgcacctacgagcacattccccccgagtgggtg
ggcaatagccgccgctttctggtctccgacgtctcggggcgctccaacctcctggccaag
ctccaggaggtgggggtggacctctccaaggaggaggcgaagcggctccttgaggaggtc
aaggccctggagtacgagggctacgcctttgagggggcggaggccagcttctacctcctg
gcccaccgcatgaaggggggaggcctgcccttccaggtggaggggttttccgtcttcgtg
cacgggagtggcctttccaccgcctgggccgaggccacggtgcgggtccgggtgggggag
agcctggagcacaccgcggcggaaagcccctatggccccgtttccgccctggaccgggcc
ttccgcaaggccatcctgggcttctaccccgagcttgcggacgtggagcttgcggactac
aaggtgcgcatcctctcgggccaggaggcgggcacgaacagcggggtgcgggtcctggtg
gagatgcgaaggggggaggagcgcttcgccaccgtgggggccagcgagaacatcctcgag
gcctccttgaaggccctcaccgacggctacgcctacgctcttctcaagccccttctggag
cgggcccttacgggctccaggggaggctag
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