Treponema pallidum subsp. pallidum Nichols: TP_0340
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Entry
TP_0340 CDS
T00016
Name
(GenBank) folylpolyglutamate synthetase (folC)
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
tpa
Treponema pallidum subsp. pallidum Nichols
Pathway
tpa00790
Folate biosynthesis
tpa01100
Metabolic pathways
tpa01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
tpa00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
TP_0340
Enzymes [BR:
tpa01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
TP_0340
6.3.2.17 tetrahydrofolate synthase
TP_0340
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
AAC65325
UniProt:
O83360
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Position
complement(362010..363482)
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AA seq
490 aa
AA seq
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MSDLSNVHQFSFPARIAASSVPHIIVRPSAHGVSHIPVHSFQDFYAWVERIRTLEKMPPS
GTPPLHRMTALARALCNPHNAYQSIHVAGTKGKGSSARMLAAILNEIGFNTGLYASPHVM
DPRERITRAGVFFSPAEYASACTHVYHTVKKTENLRDYGQATWFELITLLAFMLFAQQRM
EWSVFEVGLGGRLDATNIICPSICLLLPIEQEHTRILGTRIKSIAKEKGGIIKPYTPIFC
FDQPEDALHVFKHIAREKHAPFFYLPDMVTHIESSIKHFTHTATLSFNAAHPVGRLFARN
IHCTLALCDIVQAKNAALAACAAKYLFPTVSETLIERGLSRAYVPARFEIMQEDPLIVID
GAHTTQSIRCACRTFSSLLPSAQYILLFACAADKAVSQFPPLFSHAASEIFLTIPGTSKH
ADIQKTYHAFRTTFHQTVPIFWSEDFASIISRALYASFAQRKALLAIGSFYLAAEVKRIY
ARTCHTLPNR
NT seq
1473 nt
NT seq
+upstream
nt +downstream
nt
atgtcagaccttagcaatgtacatcagttctctttcccggcaaggattgctgcctcttcc
gtaccgcatattatagtgcgaccgagcgcacacggagtttcacatataccggtgcattct
tttcaagatttttacgcctgggttgagcgcattcgcacgcttgagaaaatgcccccaagc
ggcacaccacctctgcacaggatgactgcacttgcacgcgcgctttgtaatccacacaac
gcatatcagagcatccatgttgcgggcacgaagggaaaaggttccagcgcacgtatgctt
gcagcgatactcaatgaaattggattcaacaccgggctatacgcttctcctcacgttatg
gatccgagagagagaataacacgcgcgggtgtgtttttttcacctgccgagtatgcaagc
gcgtgcacacacgtataccacacggtgaaaaaaacagagaatctgcgcgactacggccag
gcgacgtggtttgagcttataacgctactggcgttcatgctatttgcacaacaacgcatg
gaatggtccgtttttgaagtaggacttggaggaagactagatgcaacaaacatcatttgt
cctagtatctgtctccttctccccatagaacaagaacacacgcgcatattaggaacacgt
ataaaaagtattgcaaaagaaaagggcggcattatcaaaccctatacgcctattttttgt
tttgatcagccagaagatgcattgcacgtttttaaacatatcgcgcgagaaaaacatgct
cccttcttttacttaccagatatggtcacacatattgaaagttcaataaaacacttcaca
cacactgcaactctcagttttaacgccgcgcatcctgttggcagattattcgctcgaaat
atacactgcacactcgcgttatgcgatattgttcaggcaaaaaatgcagcactggctgcg
tgcgcggcaaaatatttatttcctaccgtgagcgaaacgttaatcgagcggggactgtcc
cgtgcatacgtgccagcacgctttgaaattatgcaggaagatccactcatagtgattgac
ggtgcgcacactacgcagagtatacggtgcgcatgtcgtacgttctcttctttactacct
tctgcacaatacattttactctttgcgtgcgcggcggacaaagcagtgtcccagttcccc
cctcttttttcacatgccgccagcgaaatttttttaaccataccgggcacatctaaacat
gcagatatacaaaaaacataccacgcgtttcgtacgacatttcaccaaacagtcccaatt
ttttggagcgaagactttgcgtcaattatttcccgtgcactgtatgccagttttgcgcaa
cgtaaagcgctccttgccatcggttctttctatttagctgctgaagtaaaacgcatatac
gcacgcacctgccacaccctacctaaccgataa
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