KEGG   Treponema pallidum subsp. pallidum Nichols: TP_0732
Entry
TP_0732           CDS       T00016                                 
Name
(GenBank) methylenetetrahydrofolate dehydrogenase (folD)
  KO
K01491  methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
Organism
tpa  Treponema pallidum subsp. pallidum Nichols
Pathway
tpa00670  One carbon pool by folate
tpa00720  Other carbon fixation pathways
tpa01100  Metabolic pathways
tpa01120  Microbial metabolism in diverse environments
tpa01200  Carbon metabolism
tpa01240  Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:tpa00001]
 09100 Metabolism
  09102 Energy metabolism
   00720 Other carbon fixation pathways
    TP_0732
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    TP_0732
Enzymes [BR:tpa01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.5  methylenetetrahydrofolate dehydrogenase (NADP+)
     TP_0732
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.9  methenyltetrahydrofolate cyclohydrolase
     TP_0732
SSDB
Motif
Pfam: THF_DHG_CYH_C THF_DHG_CYH
Other DBs
NCBI-ProteinID: AAC65701
UniProt: O83714
LinkDB
Position
complement(797349..798296)
AA seq 315 aa
MDARLIDGKQAAHECTARLATRVQALRAAVGTAPFLAAVLVGDDPASCTYVAAKQRALAR
AHLRGETHRLPAHASHAQVLELIARLNEDARVHGILIQLPLPAHLDAARVCRAVAPEKDV
DGFHPLNCGALFLAQPGFVPCTPAGIVHLLRRAQVPLAGARVVIVGRSAIVGRPLAVLLA
SPGCDATVTLCHSHTRGLADICVQADILVAALGKARFIGAPFVRTGAVVIDVGIHHVPDA
TAPRGRRLCGDVDFDAVAHKVQAITPVPGGVGPMTIAMLLHNTLCAAEYAAGMIPPFRAA
LYADLDGRAAGDVPH
NT seq 948 nt   +upstreamnt  +downstreamnt
gtggacgcacgcctcatcgatggaaaacaagccgcacacgagtgtacggcgcgtcttgca
acgcgtgtgcaggcgctgcgtgcggcggtaggcacggcgccctttcttgccgcagtgctg
gtgggggatgacccggcttcttgtacctacgttgcagcaaagcagcgtgccctggctcgc
gcccacctgcggggggaaacgcaccggctgcctgctcatgcctctcacgcacaggtgtta
gaacttattgctcgtctcaatgaggacgcgcgggtgcacggcattttgatccaattgccg
ttacctgcgcatcttgacgcagcgagggtgtgccgcgcagtggcgccagaaaaagatgtc
gacggctttcatccgcttaactgtggtgcgctcttccttgcgcagcctgggtttgttccc
tgcacccctgcggggattgtgcacttgctccggcgtgcgcaggtgccgcttgcgggggca
cgcgtggtaattgtcggccgttctgccatcgttggccgtccgcttgcagtgctccttgcc
tctcccggctgtgatgcaaccgtgacgctctgtcacagtcacacgcgcggtttggcggat
atctgtgtgcaggcagatatcctcgttgcagcactgggaaaggcgcgcttcattggcgcg
ccgtttgtgcgcaccggcgccgtggttatcgatgtgggtattcatcacgtgccagatgca
actgcaccgcgcgggagaagactgtgtggtgatgtggattttgacgcagtggcgcacaag
gtgcaggcgatcacgcctgttccggggggagtaggaccgatgactatcgcgatgctgctg
cacaacacgctctgcgctgcagagtatgcagccgggatgatacccccctttagagcggcg
ctctatgccgacctagatggacgcgctgcaggcgacgtaccgcactga

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