Treponema pallidum subsp. pallidum Nichols: TP_0903
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Entry
TP_0903 CDS
T00016
Name
(GenBank) UDP-N-acetylmuramoylalanine--D-glutamate ligase (murD)
KO
K01925
UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:
6.3.2.9
]
Organism
tpa
Treponema pallidum subsp. pallidum Nichols
Pathway
tpa00470
D-Amino acid metabolism
tpa00550
Peptidoglycan biosynthesis
tpa01100
Metabolic pathways
Brite
KEGG Orthology (KO) [BR:
tpa00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
TP_0903
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
TP_0903
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
tpa01011
]
TP_0903
Enzymes [BR:
tpa01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.9 UDP-N-acetylmuramoyl-L-alanine---D-glutamate ligase
TP_0903
Peptidoglycan biosynthesis and degradation proteins [BR:
tpa01011
]
Precursor biosynthesis
Amino acid ligase
TP_0903
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Ortholog
Paralog
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
MurD-like_N
AdoHcyase_NAD
Motif
Other DBs
NCBI-ProteinID:
AAC65856
UniProt:
O83873
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All DBs
Position
984880..986478
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AA seq
532 aa
AA seq
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MEQARALLQGKTVTIMGLGVHGGGCAAACFCAEAGARLTVTDLRNADALTPSLKRLRAYP
SIRFTLGEHRLEDFENAHVVIKNPIVKGAHNIYLSAAQRAGARIETDISLFLRLSPAPLL
AVSGSKGKSSTASALCYSLRALGFPAFLGGNSTVSPLEFVRHTTPATPVVLELSSWQLAD
LRAVDAQDHTVHHAGLLRPEIAIMTPIMADHQNWYADMESYVADKQVLYAHQGTHDTLLC
NADDGWGPRFACEAQKNGVRVFWYTAQSPETACRACTPRLMERALWRATDGTYWARFAEG
DRACMLIPPQLHVPGRVLQTQVASAALAALLFAQRHSLPPSSCPPCFCAHSHSPAYANHA
SPPDYACPSAHSPFQEHTRRLAQALESYTGIEHRLEFFYEKGGLRFYNDSASTVPEATIA
ALEAFDESVVLIVGGTDKNADYQPLAQAAAKAHALYLLAGSATARLQPLLHAAQVPFYGP
FTSLEVLLQDLRARQKSPGVIVFSPGAASFELFAHEFERGTTFKSQVRIIFE
NT seq
1599 nt
NT seq
+upstream
nt +downstream
nt
gtggagcaggcgcgcgcacttcttcaaggcaaaacggtaaccatcatgggcctcggcgtg
cacggcgggggctgcgcggcagcctgcttttgtgcagaagcgggagcgcgccttacggtt
accgacctgcgaaatgctgatgcgcttaccccttccctgaaaagacttcgtgcgtacccg
tccatccgctttacgctcggtgaacaccggctggaagattttgaaaacgcgcatgttgtc
atcaaaaatcccatcgtgaagggtgcacacaacatctacctttccgctgctcaacgcgcc
ggcgcgcgcatcgaaacggatatctcccttttcctacgcctttctcccgccccgctgcta
gcagtaagcggcagcaagggaaaatcctccactgccagcgccctgtgctacagcttgcgt
gcgctgggtttccccgcctttctaggggggaatagcacagtcagcccgctggaatttgtg
cgtcacacaacgcctgcaacaccagtggttctggaactgtcgagctggcagcttgcagac
ctacgcgcagtcgatgcacaggaccacactgtacaccacgccggtctgctgcgcccggag
attgccatcatgactcccattatggctgaccatcaaaactggtatgcggatatggaaagc
tacgtggcagacaaacaggtgctatacgcacaccagggaacgcacgatacactgctgtgt
aacgcagatgacgggtggggaccccgctttgcctgcgaagcgcagaaaaacggagtgcgc
gtcttttggtatacggcccagtcgcctgagaccgcttgccgcgcgtgcaccccgcgcctc
atggagagagctctatggagagcgacggacggaacctactgggcacgttttgcagaaggt
gaccgcgcctgcatgctcatcccaccgcagctgcacgtaccgggccgtgtcctccaaacg
caagtggcgagtgcagcgcttgcagcgctcctgttcgcgcagcggcattctctacctcct
tcctcctgccccccgtgtttttgcgcacactcccattcccccgcgtacgcgaatcacgcg
tcccccccagactacgcttgtccgtccgctcacagtcccttccaagagcacacccggcgt
cttgcacaagcgctggagtcctacacgggcatcgaacaccgactagagtttttttacgaa
aaggggggactgcgtttttataacgattctgcatccactgtacctgaggcaacaattgca
gcgctggaagcctttgatgaaagcgtggttcttatcgttggcggcactgataagaatgca
gactaccaacccttggcacaggcagcagccaaggcgcacgcattgtacttgcttgcagga
agtgctacggcacggttgcaaccacttcttcatgcagcacaggtacctttttacggaccg
tttacttcccttgaggtactcctgcaggatctccgggcgcggcagaaaagcccaggcgtg
atcgtgttctctcctggggcagcgagttttgaacttttcgcccacgagtttgagcgaggt
actacctttaaatcccaggtgcgtatcatttttgaataa
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