KEGG   Treponema pallidum subsp. pallidum Nichols: TP_1008
Entry
TP_1008           CDS       T00016                                 
Name
(GenBank) ribonucleoside-diphosphate reductase, subunit alpha (nrdA)
  KO
K00525  ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
Organism
tpa  Treponema pallidum subsp. pallidum Nichols
Pathway
tpa00230  Purine metabolism
tpa00240  Pyrimidine metabolism
tpa01100  Metabolic pathways
tpa01232  Nucleotide metabolism
Module
tpa_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP
tpa_M00938  Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:tpa00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    TP_1008
   00240 Pyrimidine metabolism
    TP_1008
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:tpa03400]
    TP_1008
Enzymes [BR:tpa01000]
 1. Oxidoreductases
  1.17  Acting on CH or CH2 groups
   1.17.4  With a disulfide as acceptor
    1.17.4.1  ribonucleoside-diphosphate reductase
     TP_1008
DNA repair and recombination proteins [BR:tpa03400]
 Prokaryotic type
  Other factors with a suspected DNA repair function
   Modulation of nucleotide pools
    TP_1008
SSDB
Motif
Pfam: Ribonuc_red_lgC Ribonuc_red_lgN ATP-cone DUF1980_C
Other DBs
NCBI-ProteinID: AAC65956
UniProt: O83972
LinkDB
Position
complement(1097991..1100528)
AA seq 845 aa
MHIIKRNGEPQPYMREKIIVAISAAFRSVQNPLAPEVPAIITDLAAEVERQLFEMNRAGV
PVHVEKIQDFVEKTLTKYNHSDEVKSFILYRDDRTKKRIAREQIACCFTDSSVLGVLKEI
QQDFPFPEYSLDALASKFLLFKKEVTDERRSMQLLIKAAVELTAQEAPQWELIAARLLML
DFSLALGTSLEKLNIHSFYEKITYLEEAGLYGVYIRTHYSRAEIEEAATYLECSRDKLFT
YSSLDMILRRYVIRTRAHVPLETPQEMFLGIALHLAMNETQDRMQWVKRFYTVLSKLQVT
VATPTLSNARKPFHQLSSCFVDTVPDSLDGIYRSIDNFSQVSKFGGGMGLYFGKVRAVGA
PIRGFQGAAGGILRWIKLANDTAVAVDQLGVRQGSVAVYLDVWHKDIPEFLQLRTNNGDD
RMKAHDVFPAVCYPDLFWKTVRDNLGASWYLMCPHEILTVKGYALEDFYAEEWEKRYWDC
VKDARISKRTIPIKELVRLVLKSVVETGTPFAFYRDHANRANPNGHRGIIYCSNLCTEIA
QNMSAINLVSVKITEVDGQKVVVQTTRPGDFVVCNLASLVLSNIDLSDDKELREVVRVAV
RALDNVIDLTYYPVPYAQVTNAYYRAIGLGVSGYHHVLAQQGIDWESDEHLAFADRIFER
INRAAIEASMTIAREKGAYGCFTGSDWCTGAYFRKRGYVSEDWQRLQREVATHGMRNGYL
LAVAPTSSTSIIAGTTAGVDPIMKQYFLEEKKGMLMPRVAPSLSQKTCPLYKSAHAVEQR
WSIRAAGLRQRHIDQAQSVNLYITTDFTLKQVLDLYVYAWEVGMKSLYYVRSQSLEIDLC
GYCAS
NT seq 2538 nt   +upstreamnt  +downstreamnt
atgcatatcatcaagcgaaatggcgaaccgcaaccttacatgcgcgagaaaataattgtt
gctatcagtgctgcttttagaagtgtccagaatcctcttgctcctgaagttcctgctatc
atcacagatcttgccgcggaggttgagcgacagctttttgagatgaaccgtgcgggcgtt
cctgttcacgtggaaaagattcaggactttgtcgaaaagactcttaccaaatacaatcac
agcgatgaagtgaagagttttatcctgtaccgtgacgatcgcacaaaaaagcgtattgca
agagaacagattgcgtgctgttttactgactcttcagtgctcggtgtactgaaagaaatc
caacaagactttccgtttcctgagtacagtctcgatgcactcgccagtaagttcctgctc
tttaaaaaagaagttacggacgagcgtcggagtatgcaactgcttattaaggcagcggtg
gaactgactgcccaagaggctccccagtgggagcttattgctgcgcgcttgcttatgctc
gacttttcactcgcgctaggaacatctttggaaaagttaaatattcactccttctacgag
aaaataacttatcttgaagaggccggtctatatggggtgtacatccgcacgcactatagt
cgggcagaaattgaggaagctgccacgtatcttgagtgtagtcgcgataaattgtttacg
tacagcagtctggatatgattctgcgtcgctatgtgatcagaacgcgtgcgcatgtacct
cttgaaactcctcaggagatgtttctcggtattgcactgcatctagcgatgaatgaaacc
caagatcgtatgcaatgggtaaaacgcttttatacagtcctcagcaagttgcaggttacg
gtcgcaacacctacgctttcaaacgcgcgcaaaccttttcatcaactttcctcgtgtttc
gttgatacggtgccagattcgctcgacggtatctaccgcagcatcgacaatttttcccag
gtatctaagtttgggggagggatggggctgtactttggaaaagtgcgtgcggtaggcgct
cccattcgggggttccagggtgctgcaggtggtattctccgttggattaagctcgccaat
gatactgcagttgcagtagatcaactaggagtacgccaaggctcggtggcagtgtatttg
gatgtatggcacaaggatattccggaatttttgcaattacggactaataatggggatgac
cgcatgaaagcacatgacgtatttcctgcggtctgttatccagatttgttctggaagaca
gtacgcgataatttgggggcgtcgtggtatttaatgtgtccgcatgagattcttacggtg
aaaggctatgctttggaggatttttatgcggaggaatgggagaagcgctactgggattgt
gtaaaggatgcgcgtatctctaagaggaccattccgattaaggagttggtgcgcttggtg
ctaaaatctgtggtggaaaccggtactccctttgcgttttaccgagatcatgcaaaccgt
gcaaatcccaatgggcatcggggaattatttactgttctaatttgtgtactgaaattgcg
cagaacatgagcgctattaatttagtaagcgtaaaaatcaccgaggttgatggacaaaag
gtagtggtgcagacaacgcggccgggggattttgttgtatgtaacctcgcgtcgttggtg
ctgagcaatattgacctttcagatgataaggagttgcgcgaggtagtgcgtgtggcggta
cgtgcattagacaacgtgatcgatttgacatattatccggttccctatgcacaggtaacc
aatgcgtattatcgtgctattggtttaggtgtttcaggctaccatcacgtgcttgcccag
caaggaatcgattgggaaagtgatgaacatcttgcatttgcggacagaatatttgagcgc
attaaccgtgccgcaattgaagcgagtatgacaatcgcgcgcgagaagggtgcgtatggg
tgtttcactgggagcgattggtgtaccggtgcgtattttcgcaaacgcggctatgtctct
gaagactggcaacgtttgcagcgtgaggtagcaacacatgggatgcgcaacggttactta
cttgcagtcgcgccaactagttctacgtctatcattgcagggaccactgcgggtgtagat
cctattatgaagcagtatttcctcgaggaaaagaaaggcatgctaatgccacgcgtagct
ccttctctttcgcagaagacctgtccactgtataaaagtgcacacgcagtggagcagcgt
tggagtatccgtgctgcgggtctgcggcaacgacatattgaccaggcacagtcagtgaat
ctgtacattacaacggactttacactgaagcaggttctagatttgtacgtgtatgcgtgg
gaagtaggaatgaagtcactatactacgtacgaagccagtcgctcgaaatagatttgtgt
gggtattgtgcctcgtag

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