KEGG   Tympanuchus pallidicinctus (lesser prairie-chicken): 128082424
Entry
128082424         CDS       T08967                                 
Symbol
PIK3CA
Name
(RefSeq) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
  KO
K00922  phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
Organism
tpai  Tympanuchus pallidicinctus (lesser prairie-chicken)
Pathway
tpai00562  Inositol phosphate metabolism
tpai01100  Metabolic pathways
tpai04012  ErbB signaling pathway
tpai04068  FoxO signaling pathway
tpai04070  Phosphatidylinositol signaling system
tpai04081  Hormone signaling
tpai04140  Autophagy - animal
tpai04150  mTOR signaling pathway
tpai04210  Apoptosis
tpai04218  Cellular senescence
tpai04370  VEGF signaling pathway
tpai04510  Focal adhesion
tpai04620  Toll-like receptor signaling pathway
tpai04625  C-type lectin receptor signaling pathway
tpai04810  Regulation of actin cytoskeleton
tpai04910  Insulin signaling pathway
tpai04914  Progesterone-mediated oocyte maturation
tpai05100  Bacterial invasion of epithelial cells
tpai05132  Salmonella infection
tpai05164  Influenza A
tpai05168  Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:tpai00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    128082424 (PIK3CA)
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    128082424 (PIK3CA)
   04370 VEGF signaling pathway
    128082424 (PIK3CA)
   04068 FoxO signaling pathway
    128082424 (PIK3CA)
   04070 Phosphatidylinositol signaling system
    128082424 (PIK3CA)
   04150 mTOR signaling pathway
    128082424 (PIK3CA)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    128082424 (PIK3CA)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    128082424 (PIK3CA)
  09143 Cell growth and death
   04210 Apoptosis
    128082424 (PIK3CA)
   04218 Cellular senescence
    128082424 (PIK3CA)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    128082424 (PIK3CA)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    128082424 (PIK3CA)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    128082424 (PIK3CA)
   04625 C-type lectin receptor signaling pathway
    128082424 (PIK3CA)
  09152 Endocrine system
   04910 Insulin signaling pathway
    128082424 (PIK3CA)
   04914 Progesterone-mediated oocyte maturation
    128082424 (PIK3CA)
 09160 Human Diseases
  09172 Infectious disease: viral
   05164 Influenza A
    128082424 (PIK3CA)
   05168 Herpes simplex virus 1 infection
    128082424 (PIK3CA)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    128082424 (PIK3CA)
   05100 Bacterial invasion of epithelial cells
    128082424 (PIK3CA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:tpai04131]
    128082424 (PIK3CA)
Enzymes [BR:tpai01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     128082424 (PIK3CA)
Membrane trafficking [BR:tpai04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    128082424 (PIK3CA)
SSDB
Motif
Pfam: PI3Ka PI3_PI4_kinase PI3K_rbd PI3K_C2 PI3K_p85B DUF2321 ABC1 Ribosomal_S15
Other DBs
NCBI-GeneID: 128082424
NCBI-ProteinID: XP_052542493
LinkDB
Position
Unknown
AA seq 1068 aa
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPICEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
NT seq 3207 nt   +upstreamnt  +downstreamnt
atgcctccccgaccatcatctggtgaactatggggcatccacttgatgcccccgaggatc
cttgtggagtgtcttctcccaaacggaatgatagtgactctagaatgcctccgtgaggct
acattactaactatcaaacatgaactttttaaagaagccagaaaataccctctctatcag
ctccttcaagatgaatcttcttacatttttgtaagtgttacgcaagaagcagaaagagaa
gaattttttgatgaaacacggagactttgtgacctgcggctatttcagcctttcctaaaa
gtcattgaaccagtaggtaacagagaagaaaagatacttaacagagaaataggttttgca
attggcatgcccatctgtgagtttgacatggttaaggatcctgaagtacaagatttcaga
agaaatattcttaatgtttgtaaagaagcagtagatcttcgagatgccaatgctccgcac
agtagagcattgtatgtctgtcctccaaatgtagagtcttcacctgagctacccaaacac
atatacaataaactagataaagggcaaataatagtggtgatatgggtaatagtttcacct
aacaatgataagcagaagtacaccttaaaaatcaatcatgactgtgtgcctgagcaagtt
attgctgaagcaattaggaagaaaacacgaagtatgttgctgtcatctgaacaactgaag
ctctgcgtgttggagtaccagggcaagtatattttgaaagtgtgcggctgtgatgaatac
ctgctagaaaaatatcctctgagccagtataagtacataagaagttgtataatgcttggt
cgcatgcccaatctgatgctgatggctaaagaaagtctatatacccagctgccactggat
acctttacaatgccatcttactccaggcgtatctctacagctacaccctacatgaatgga
gaagctacagccaaatcgctctggactataaacagtgctctcagaataagaatcctctgt
gcaacctatgtaaatgtgaacattagagacattgacaagatctacgttagaacaggtatc
taccatggaggagaacctttatgtgacaatgtgaacactcagagggtaccttgttctaat
cccagatggaatgaatggctgctgtatgacatgtacattcctgatcttccacgtgctgct
cggctctgcctttctatctgttctgttaaaggccggaagggtgctaaagaggagcactgt
ccattggcttggggaaatataaacatgtttgactacacagacactcttgtatctgggaaa
atggctttgaatctttgggcagtaccccatggactggaggatttgttgaatcctattggt
gttactggatcaaatccgaataaggaaactccatgtttagagctggaatttgattggttt
agcaatcctgtgaagtttccagatatgacagtgattgaagagcatgccaattggacaatc
tcacgtgaactaggctttaattacagctatgcgggactgagtaatagaatagctagagac
aatgaattaagagaaagtgacaaggagcaactgcgagccatatgtacacgggatcccttg
tctgaaatcactgagcaagagaaggacttcctctggagccacagacactattgcgtaaat
accccggaaattctgcccaaattacttctgtctgttaaatggaattctagagatgaagtg
gctcagatgtactgtctggtgaaagattggcctccaatcaagccagagcaagcaatggag
cttttggattgcaattatccagatccaatggtgcgagcctttgcagttcggtgtctagag
aagtacttaacagatgacaagctgtctcagtacttaatccagctagtacaggttctgaaa
tatgaacagtacttagataatcaactggtgagatttttactcaagaaggcactgaccaat
caacggataggacacttcttcttctggcatttaaagtctgaaatgcacaataaaactgta
agtcagaggtttggtttacttctggagtcctattgtcgagcgtgtggaatgtacctaaag
catctgagcaggcaggtggaggctatggagaagttgattaacctcacagatattctcaag
caggaaaagaaagatgagacccagaaggtgcagatgaagtttcttgttgaacaaatgaga
cgtccagattttatggatgctttacaaggctttatctctcctcttaatcctgctcatcaa
ctaggaaatcttcggcttgaggagtgcagaataatgtcatctgcaaagagacccctgtgg
ttaaactgggaaaacccagatattatgtctgaattgctatttcagaacaatgagataatc
tttaaaaatggagatgacttacgtcaagacatgctgacacttcagataattagaattatg
gaaaacatttggcaaaaccaaggtcttgatcttcggatgttgccttacggttgtctgtct
attggtgactgcgtgggactcattgaggtagtgagaagttctcatacgatcatgcagatt
cagtgtaaaggaggcttaaagggagcattgcagttcaacagccataccttgcatcagtgg
ctcaaggacaagaacaaaggagaaatgtatgatgcagctattgacttgtttacacgttct
tgtgctggctactgtgttgctacctttatactgggcattggtgatcgccacaacagtaac
atcatggtgaaagatgatggacaactgtttcacattgactttggccacttccttgaccac
aagaagaagaaatttggctacaaaagagagcgtgtgccctttgtcttaacacaggacttt
ctaatagtgattagtaaaggagcccaagaatgcaccaaaacaagggagtttgaaaggttt
caagagatgtgttacaaggcttatctagcaattcggcagcatgccaatctgttcataaat
ctcttctccatgatgcttggctcaggaatgccagaactgcagtcctttgatgatattgcg
tacattcgaaagacccttgcattggataaaactgagcaggaagctcttgagtacttcatg
aagcaaatgaatgatgctcaccatggtggctggacaacaaaaatggactggatcttccac
acaataaagcaacatgctttgaactga

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