Treponema pallidum subsp. pallidum Sea 81-4: TPSea814_000340
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Entry
TPSea814_000340 CDS
T03185
Name
(GenBank) folylpolyglutamate synthetase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
tpas
Treponema pallidum subsp. pallidum Sea 81-4
Pathway
tpas00790
Folate biosynthesis
tpas01100
Metabolic pathways
tpas01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
tpas00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
TPSea814_000340
Enzymes [BR:
tpas01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
TPSea814_000340
6.3.2.17 tetrahydrofolate synthase
TPSea814_000340
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
AHN67023
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Position
complement(363251..364612)
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AA seq
453 aa
AA seq
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MHSFQDFYAWVERIRTLEKMPPSGTPPLHRMTALARALCNPHNAYQSIHVAGTKGKGSSA
RMLAAILNEIGFNTGLYASPHVMDPRERITRAGVFFSPAEYASACTHVYHTVKKTENLRD
YGQATWFELITLLAFMLFAQQRMEWSVFEVGLGGRLDATNIICPSICLLLPIEQEHTRIL
GTRIKSIAKEKGGIIKPYTPIFCFDQPEDALHVFKHIAREKHAPFFYLPDMVTHIESSIK
HFTHTATLSFNAAHPVGRLFARNIHCTLALCDIVQAKNAALAACAAKYLFPTVSETLIER
GLSRAYVPARFEIMQEDPLIVIDGAHTTQSIRCACRTFSSLLPSAQYILLFACAADKAVS
QFPPLFSHAASEIFLTIPGTSKHADIQKTYHAFRTTFHQTVPIFWSEDFASIISRALYAS
FAQRKALLAIGSFYLAAEVKRIYARTCHTLPNR
NT seq
1362 nt
NT seq
+upstream
nt +downstream
nt
gtgcattcttttcaagatttttacgcctgggttgagcgcattcgcacgcttgagaaaatg
cccccaagcggcacaccacctctgcacaggatgactgcacttgcacgcgcgctttgtaat
ccacacaacgcatatcagagcatccatgttgcgggcacgaagggaaaaggttccagcgca
cgtatgcttgcagcgatactcaatgaaattggattcaacaccgggctatacgcttctcct
cacgttatggatccgagagagagaataacacgcgcgggtgtgtttttttcacctgccgag
tatgcaagcgcgtgcacacacgtataccacacggtgaaaaaaacagagaatctgcgcgac
tacggccaggcgacgtggtttgagcttataacgctactggcgttcatgctatttgcacaa
caacgcatggaatggtccgtttttgaagtaggacttggaggaagactagatgcaacaaac
atcatttgtcctagtatctgtctccttctccccatagaacaagaacacacgcgcatatta
ggaacacgtataaaaagtattgcaaaagaaaagggcggcattatcaaaccctatacgcct
attttttgttttgatcagccagaagatgcattgcacgtttttaaacatatcgcgcgagaa
aaacatgctcccttcttttacttaccagatatggtcacacatattgaaagttcaataaaa
cacttcacacacactgcaactctcagttttaacgccgcgcatcctgttggcagattattc
gctcgaaatatacactgcacactcgcgttatgcgatattgttcaggcaaaaaatgcagca
ctggctgcgtgcgcggcaaaatatttatttcctaccgtgagcgaaacgttaatcgagcgg
ggactgtcccgtgcatacgtgccagcacgctttgaaattatgcaggaagatccactcata
gtgattgacggtgcgcacactacgcagagtatacggtgcgcatgtcgtacgttctcttct
ttactaccttctgcacaatacattttactctttgcgtgcgcggcggacaaagcagtgtcc
cagttcccccctcttttttcacatgccgccagcgaaatttttttaaccataccgggcaca
tctaaacatgcagatatacaaaaaacataccacgcgtttcgtacgacatttcaccaaaca
gtcccaattttttggagcgaagactttgcgtcaattatttcccgtgcactgtatgccagt
tttgcgcaacgtaaagcgctccttgccatcggttctttctatttagctgctgaagtaaaa
cgcatatacgcacgcacctgccacaccctacctaaccgataa
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