Treponema pedis: TPE_1668
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Entry
TPE_1668 CDS
T02803
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
tped
Treponema pedis
Pathway
tped00790
Folate biosynthesis
tped01100
Metabolic pathways
tped01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
tped00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
TPE_1668
Enzymes [BR:
tped01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
TPE_1668
6.3.2.17 tetrahydrofolate synthase
TPE_1668
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Paralog
GFIT
Motif
Pfam:
HPPK
Mur_ligase_C
Mur_ligase_M
FOL3_C
ANAPC3
Motif
Other DBs
NCBI-ProteinID:
AGT44150
UniProt:
S5ZV75
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Position
1703340..1705085
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AA seq
581 aa
AA seq
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MEKNVWIALGGNIGDREGYLKKALELMEKRGIKPVLISSFIETKAYGKTDQADFINAVCK
AKTNLSPLELLHTLLDIEKTLKRVRIIKWGPRTIDLDILFYEDEVLKTEELTVPHPEMEK
RSFVLKPLSEISPEKLHPVCKKTVKTLLDNLELSEETAWLNARMQLGIKPGLENIRALLS
RLGNPHKEYPCLHIAGTNGKGSLCAYLSCVLENAGYKTGLFTSPAIETLTEQFRINRKNI
PDSELLSVLKHIHSIVDDMEKHNMFPTYFEIITAIGFEYFKRRNADIAVIETGMGGLYDS
TNVIEKPLASFITTIDYDHTDYLGDTLEKIAEHKAGIIKKDSYVFCYPNGSNITDIFKKA
AKNAGSQIYVLNESEINSCSVSLTETVFSYGKFKDIHLSMRGKHQVNNAALAILGLTVLR
AEQKLHFTDEQLYCGLNEAFLTARIEVLQKEPLFILDGSHNTEGIKALTETLSHLNYKRL
ILGIGILKDKNYGDMLKMLIPEASEIVVTEVPVARALKAEELFKEASLLHSNVYCEKNIF
AALKKTFSAAEEEDLILWCGSLYLAGEIKKAYYFLRQEHEK
NT seq
1746 nt
NT seq
+upstream
nt +downstream
nt
atggaaaaaaatgtttggatagctctgggcggaaatatcggcgatagggaagggtatctt
aaaaaagccttggagcttatggaaaaaagaggtataaaaccggttttaatttcttcattt
atagaaacaaaggcttacggtaaaaccgaccaggcggattttattaacgcagtatgtaag
gcaaaaacaaatttatcccccttagagcttttgcatacattattggatatagaaaaaact
cttaaaagagtgaggataattaaatggggccctcgcactatagatttggatattcttttt
tatgaagatgaggtattaaaaaccgaagaattaaccgttcctcatcccgaaatggaaaaa
cgaagttttgttttaaaacctctttcggaaataagccccgaaaaacttcatcccgtatgt
aaaaaaaccgtaaaaaccttactggataatcttgagctgtcggaagaaacggcttggctt
aatgcaagaatgcaattgggcattaagcccggacttgaaaatataagagctttgttatcc
cgtttgggaaatcctcataaagaatatccatgtcttcatatcgcgggaacaaacggaaaa
ggctctctttgcgcatatctttcatgtgtacttgaaaatgccggttataaaacaggttta
tttacttctcctgcaattgaaacccttacggaacagttccgaattaaccgtaaaaatata
ccggactccgaacttttatcggttttaaaacacatacattccattgttgacgatatggaa
aagcataatatgtttccgacatattttgaaattataactgcaatagggtttgaatatttt
aaacgccgaaatgcggatatcgcagttatcgaaaccggaatgggaggcctttatgattct
acaaatgttatagaaaagcctcttgcgtcctttattacaacaattgattacgaccatacg
gattatttgggagatactttagaaaaaatagcggaacataaggccggaattataaaaaaa
gattcctatgttttttgctatcctaacggaagcaatataacggatatttttaaaaaagcg
gcaaaaaatgcgggctcgcaaatttatgttttaaacgaaagcgaaataaactcctgttca
gtgagtttaactgaaacggtcttttcttacggaaaatttaaagatatacatttatctatg
cgcggaaaacatcaggtaaataatgccgctttggcaattttagggcttaccgttttacgg
gcggaacaaaaattgcattttaccgatgaacagttatactgcggtttaaacgaggccttt
cttacggcgcgtattgaagtgcttcaaaaagagcccttatttatacttgacggttcccat
aatacggaaggaattaaagccttaaccgaaactctttcacaccttaattataagcgtttg
attttgggtatagggattttaaaagacaaaaattacggcgatatgcttaaaatgttaata
cccgaggcttcggaaattgtagttacggaagttccggttgcaagggccttaaaagcggaa
gaattgtttaaagaagcctctttattgcactcaaatgtatattgtgaaaaaaatatcttt
gccgcattgaaaaaaacattttcggcagccgaagaagaagatttgatattgtggtgcggc
tccttatatttggcgggagaaataaaaaaggcatattattttttacgacaagaacacgaa
aaatag
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