Treponema primitia: TREPR_0367
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Entry
TREPR_0367 CDS
T01507
Name
(GenBank) D-alanine--D-alanine ligase
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
tpi
Treponema primitia
Pathway
tpi00470
D-Amino acid metabolism
tpi00550
Peptidoglycan biosynthesis
tpi01100
Metabolic pathways
tpi01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
tpi00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
TREPR_0367
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
TREPR_0367
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
TREPR_0367
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
tpi01011
]
TREPR_0367
Enzymes [BR:
tpi01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
TREPR_0367
Peptidoglycan biosynthesis and degradation proteins [BR:
tpi01011
]
Precursor biosynthesis
Amino acid ligase
TREPR_0367
BRITE hierarchy
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Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
CPSase_L_D2
ATP-grasp
ATP-grasp_4
ATP-grasp_3
Motif
Other DBs
NCBI-ProteinID:
AEF83734
UniProt:
F5YN18
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All DBs
Position
3980496..3981674
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AA seq
392 aa
AA seq
DB search
MRIRVGVLFGGKSVEHEVSVISGIQAINAFDQEKYEIIPIYMTREGELYTGDVADKIEEY
RDIPALLKKLQRVTLINEAGKYLLIKYPVKAWGKQSCGEVDLIFPIVHGTNVEDGALQGY
LKTLSIPFAGCDVCASAVGMDKYVQKAVLKYNNIPVLDGVRVLSSAYYKDTEKLLNEIEQ
FAPYPIIVKPSNLGSSIGIKKAFNREELTDAFEYTFQYAHTALVEHALTNFREINCAVLG
DQDSAIASECEEPINTDAILSYKDKYVSGDKTGSKGMSSAKRILPADLSPELREEIRSLA
LKTFQALGCNGVSRIDLFVDKDTNTVLVNEINTIPGSLSFYLWEPVGVPYKELLDRLVSL
TLKREREESSLSFSIETNILVNFAGGAKGGKR
NT seq
1179 nt
NT seq
+upstream
nt +downstream
nt
atgcggatacgggttggggttttatttggcgggaagagcgtggagcacgaagtttcggtc
atttccggcatacaggcaatcaatgcctttgaccaggaaaagtacgaaatcattccgatt
tatatgacccgggaaggggaactctacaccggggacgtagcagacaagatagaggaatac
cgggatatccccgctcttttaaaaaaactccagcgggttaccctgatcaacgaagccggc
aaataccttttgatcaaatacccggttaaagcctggggcaaacagagctgcggcgaagtg
gaccttatcttccccatagtacacggcaccaatgtggaagacggcgcactccagggctat
ttgaaaaccctgtccatcccctttgcaggctgcgatgtatgcgcctctgcagtaggcatg
gataagtacgttcagaaagcagtcttaaagtacaacaatatccctgtgctggacggtgtg
cgtgttttatccagcgcctattacaaggacacagaaaaactgctcaatgaaattgaacaa
ttcgccccctatcccataatagtaaaaccctcgaacctgggttccagcataggcatcaaa
aaagcctttaaccgcgaagaactgacagacgcctttgaatacacctttcagtacgcccac
acggccctggtagaacacgctttgaccaatttcagggaaattaactgcgccgtgctgggc
gatcaggattcagccatcgcctctgagtgtgaagagcccatcaatacggacgccatcctg
agctataaggataaatacgtgtccggtgacaaaacaggctccaaggggatgagttccgcc
aaacggatactgcccgcggacctaagcccggaactcagggaagaaatccgttccctggcg
ctgaaaacctttcaggccctgggctgcaacggggtctcccgaatagatttatttgtagat
aaagacactaatactgtgctggtcaatgagatcaacaccatccccggttccctgtccttt
tatctctgggagcccgtgggagtgccctacaaggaactcctggataggcttgtcagtctg
accctgaaacgggagcgggaggagtcgagcttgtcgttttcaatagagactaatatttta
gttaattttgcaggcggggctaagggcggaaagaggtaa
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