Candidatus Tremblaya princeps PCIT: TPPCIT_048
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Entry
TPPCIT_048 CDS
T01563
Symbol
leuA
Name
(GenBank) putative 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
tpn
Candidatus Tremblaya princeps PCIT
Pathway
tpn00290
Valine, leucine and isoleucine biosynthesis
tpn00620
Pyruvate metabolism
tpn01100
Metabolic pathways
tpn01110
Biosynthesis of secondary metabolites
tpn01210
2-Oxocarboxylic acid metabolism
tpn01230
Biosynthesis of amino acids
Module
tpn_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
tpn00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
TPPCIT_048 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
TPPCIT_048 (leuA)
Enzymes [BR:
tpn01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
TPPCIT_048 (leuA)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
HCS_D2
DUF7218
Motif
Other DBs
NCBI-ProteinID:
AEI75117
UniProt:
F7XYE1
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All DBs
Position
45288..46463
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AA seq
391 aa
AA seq
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MARSMRRRLISLLDTTLRDGEQAPGILMGPDSKASMARRLELAGVDVVEAGFAASSASDF
EAIRRISCCVRGCVVCSLARAVGHDVRKAAKALEFARHPRIHVFIGSSRLHMAEKLRMHP
LEVVDRAAAMVRLARAYCDDVEFSPEDSSRADPSFLCYLARAAVEAGATVVNLTDTVGHG
IPEQLSDVAGMLCRSVTISDRVTLSVHCHNDVGLAIANTMAAIACGAGQAECTVTGIGER
AGNAALEEVVVAAGLSRSGAGMDVRVDARHMRSLALLASAIARRRLHATKPVVGCHAFAH
ASGIHQDGVIKNRRTYEALRAEDVGGRGGSIVLGKLSGAHALRDRLEIGGVTIGAIGINR
LAIMMKGLASHLPVVYGSALAALHARADRPC
NT seq
1176 nt
NT seq
+upstream
nt +downstream
nt
atggcgcgtagcatgcgtaggcgcctgatctcccttctggatactacgctaagggatgga
gagcaggcgccgggcatactaatggggccagattctaaggcctcgatggcccgacggctg
gagctagcgggcgtggatgtcgtcgaggctgggttcgccgcaagctcagcctcagacttt
gaggcaatccgtcgcatatcttgctgtgtacggggttgcgtggtgtgctcgctagcaaga
gctgtcggacatgatgtcaggaaggcagccaaggctctcgagttcgctcggcaccctagg
atccatgttttcatagggtcgtcaaggttgcacatggcggaaaagctaaggatgcatcca
cttgaggtggttgacagggctgcggcgatggtcaggctggcaagggcatattgcgacgac
gtggaattctcgcccgaggattccagcagagctgatccttcgttcctgtgctacctggct
cgtgcggccgtagaagctggcgccacagtagtgaacttaactgacactgttggccatggc
atcccggagcagcttagcgacgttgctggtatgctgtgccgctctgtgaccatatctgac
agggtcacgctttctgtacactgccataacgacgttgggctggctatcgctaacactatg
gcagcaatagcatgcggcgcgggacaggcggaatgcactgtgaccggcataggagagagg
gctggtaacgcggcacttgaggaggtcgtggttgcagctgggctctcgcgctccggcgct
gggatggacgttcgcgtggacgctaggcacatgaggtctcttgcactgcttgcgtccgcg
attgcacgacggcgtttgcatgcaactaagcctgtggttggatgccatgccttcgcacac
gcctcaggcatacatcaggacggagttataaagaaccgcaggacatacgaggcactaagg
gctgaggacgttggtggaagaggcggtagcatagtgctagggaagctttccggtgcgcat
gcattgagggatcggctcgaaatcggtggggtcaccattggtgcaattggtattaatagg
ctggctattatgatgaaggggctagcaagccatttacccgtagtatatggatccgcactg
gctgcgctccatgccagagccgaccgtccttgctag
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