Tsukamurella paurometabola: Tpau_1377
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Entry
Tpau_1377 CDS
T01228
Name
(GenBank) Uroporphyrinogen III synthase HEM4
KO
K01719
uroporphyrinogen-III synthase [EC:
4.2.1.75
]
Organism
tpr
Tsukamurella paurometabola
Pathway
tpr00860
Porphyrin metabolism
tpr01100
Metabolic pathways
tpr01110
Biosynthesis of secondary metabolites
tpr01120
Microbial metabolism in diverse environments
tpr01240
Biosynthesis of cofactors
Module
tpr_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
tpr_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
tpr00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
Tpau_1377
Enzymes [BR:
tpr01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
Tpau_1377
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Gene cluster
GFIT
Motif
Pfam:
HEM4
Trans_reg_C
MarR_2
Motif
Other DBs
NCBI-ProteinID:
ADG78005
UniProt:
D5UWY3
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All DBs
Position
1441481..1442617
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AA seq
378 aa
AA seq
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MTGPTTEASATPLLGFTVAVTAARRADELSTLLIRRGAAVVAAPAISMVPLSDDVRLRAA
TDELLTAPPDLLVATTGIGFRGWLEAAEGWGVAEGLVAALGGGRVISRGPKATGALRAAG
LREEWSPKSESSAEVLSHLAGEDLHGQRVAVQLHGATDDWDPNPGLLDGLRDLGAEIVPV
PVYRWEQPEDLSGLDRIVEAIALAEVDAVTFTSAPAAASLLERAVELGVADSVRAALTGP
VVAYCVGPVTATPLQREGIESVTPERMRLGALARLVEQDLPGRRPDLRVAGHSLGLRARG
AVVDGAERDLTPTSITLLRLLAREPGDVVSRDELLAALGGDDPHAVEAAVARLRTGLGHK
EIIATVVKRGYRLALDEH
NT seq
1137 nt
NT seq
+upstream
nt +downstream
nt
atgaccggtccgacgaccgaggcctcggccaccccacttctcggcttcaccgtggccgtg
accgccgcccgccgcgccgacgagctgtccactctgctcatccggcgcggcgccgccgtg
gtcgcggcccccgcgatcagcatggtgccgctgtccgatgatgtgcggttgcgcgccgcc
acggacgagttgctcacggcaccaccggacctgctcgtcgccaccaccggcatcggtttc
cgcggctggctggaggccgccgagggctggggcgtcgcggagggcctcgtggccgccctt
ggcggcggccgggtgatctcccgcggacccaaggccaccggcgctctgcgcgccgccggt
ttgcgcgaggagtggtcgcccaaatcggaatcgtcggcggaggtgctcagtcacctcgcg
ggggaggatctgcacgggcagcgggtcgccgtccagctgcacggcgcgaccgacgactgg
gaccccaacccgggtttgctcgacggactgcgggacctgggcgcggagatcgtgccggtg
cccgtgtaccggtgggagcagccggaggacttatcgggcctcgaccgcatcgtcgaggcg
atcgctctcgccgaggtcgacgccgtcaccttcacttctgctcctgccgcggcctcgctg
ttggagcgtgccgtcgagctcggcgtcgccgactcggtgcgcgccgccctcaccggcccg
gtggtggcgtactgcgtggggccggtcaccgcgaccccgctgcagcgtgaggggatcgaa
tcggtgacccccgagcggatgcggctcggcgccctggcacggctggtcgaacaggacctt
ccgggccgcaggccggacctgcgggtggccgggcacagcctcggactacgcgcgcgcggc
gccgtcgtcgacggtgccgaacgcgacctcacgcccacctcgatcaccctgctccgcctg
ctcgcgcgcgagcccggcgatgtggtctcccgcgacgagttgctcgccgcgctcggcgga
gacgatccgcacgccgtcgaggcggccgtcgcccggttgcgaaccgggctgggccacaag
gagatcatcgcgacggtggtcaagcggggataccggcttgcgctcgacgagcactga
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