Thermococcus profundus: A3L09_08520
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Entry
A3L09_08520 CDS
T05153
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K23269
phosphoribosylformylglycinamidine synthase subunit PurL [EC:
6.3.5.3
]
Organism
tprf
Thermococcus profundus
Pathway
tprf00230
Purine metabolism
tprf01100
Metabolic pathways
tprf01110
Biosynthesis of secondary metabolites
Module
tprf_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
tprf00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
A3L09_08520
Enzymes [BR:
tprf01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
A3L09_08520
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Motif
Pfam:
AIRS_C
AIRS
FGAR-AT_linker
NfeD
Motif
Other DBs
NCBI-ProteinID:
ASJ03295
UniProt:
A0A2Z2MF39
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All DBs
Position
1581592..1583733
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AA seq
713 aa
AA seq
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MFPHEEKLTRERLGRKPNEVEKAMLEVMWSEHASYKSSRPLLKLLPTENEHVVLGPGEDA
GIVKFDDETWIVVGIESHNHPSAVEPYGGAATGVGGIVRDILCMGARPIALLDPIRFGPL
EKERNRYLLHGVVKGIADYGNRIGVPTVGGETEFDGSLDNYTLVNVACIGTMRPEHLVHS
YVGEAGLKLVLVGNRTGRDGIHGVTFASEELSENAEEEDRSAVQIPDPFTEKLLIEATLE
AVYTGKVRALKDLGGGGLTCASSEMAGKKGFGAIIYADRVPLREPNMTPAEVMISESQER
MLLAVKPENVEEIGRIFDKYGLEWTVIGETIEEPRYVVYWNGEKVADLPIELLTDVPTIE
WEMKPYSLEKDVETPDVSFSEAFDLVWSSPNILSKRWVWEQYDHEVQGRTVVKPGFDAAV
LRINERYGLAFVADGNPNHSHLNPYHGAMGAVAEVVRNLVSVGAEPLALVDNLNFASPER
PEVYWSFAETVRGLADAARAFGLAYVSGNVSFYNEVVDRPIKPTPVVAGLGKVELEKIPG
FGLEDGLLIGIVGITSKELGGSELYARLSITGGIAPRVNLEEEKTNAEGILEAIKRGLVR
AVHDVSKGGIAVALAEMAVASRVGFTADLSKVPAETSNPIEVAFSESHGRYIVAFPEESL
EKLKAIFRHFTVIGRAGGSEAVFLWGKEELLRKPVSKLKEVHESLPKLLGEEE
NT seq
2142 nt
NT seq
+upstream
nt +downstream
nt
atgttcccgcatgaggagaagctcacccgcgaaaggctcggaaggaagccgaacgaagtg
gagaaggccatgctcgaggtcatgtggagcgagcacgcctcatataaatcgagcaggccc
cttcttaagctcctgccaacggagaacgagcacgttgttctgggcccgggagaggatgcc
ggaatagtgaagttcgatgacgagacctggatagtcgtcgggatagagagccacaaccac
ccctcggctgttgaaccctatggcggtgccgccacgggtgtcggcggaatcgttagggat
attctgtgcatgggtgcaaggccgatagctttgcttgatccgatacgcttcgggccgctt
gagaaggagaggaaccgctacctcctccatggagtcgtgaagggaatagcggactacggc
aacaggataggcgttccaacagtcggcggtgaaaccgagttcgacgggagcctcgataac
tacacgctcgttaacgttgcatgcatcgggacaatgagaccggagcacctcgtccacagc
tacgttggggaagcgggactaaagctcgtcctcgttggcaacagaaccggaagggacgga
attcatggcgtaaccttcgcgagcgaggagctgagcgagaacgctgaagaggaagaccgc
tccgcggtgcagattcctgaccccttcacggaaaagctcctaattgaagccacgcttgag
gcagtctacacagggaaggttagagcgctcaaagacctcgggggagggggtttaacctgc
gcctcctcggagatggcggggaagaagggctttggcgcaatcatctacgccgaccgcgtc
ccgcttagggagccgaacatgacgccggcggaggtcatgatatccgagagccaggagagg
atgctccttgctgtaaaacccgagaacgttgaagagattgggaggattttcgataagtac
ggccttgaatggacagtcatcggagaaaccatcgaggaaccgcgctacgtcgtctactgg
aacggcgaaaaagtcgcggaccttccaatagaactcctcacggacgtcccgacaatagag
tgggagatgaagccatacagccttgagaaggacgtcgaaactccagatgtaagcttctct
gaggcctttgatctcgtctggagcagtccgaacatccttagtaagcgctgggtatgggag
cagtatgatcacgaggttcagggaaggaccgtcgtgaagccgggcttcgacgcggccgtg
ctcagaataaacgagcgctacggattagcgttcgtcgcagatggaaaccccaaccacagc
cacctgaacccgtaccacggggctatgggagccgttgcagaggtcgttaggaacctcgtg
agcgtgggtgctgagcctttagcgctcgttgacaacctcaacttcgcctctccggagagg
ccggaagtatactggagctttgccgagacggttagagggctggccgatgccgccagagcc
tttggcttagcgtacgtgagcggaaacgtcagcttctacaacgaagtcgttgacagaccg
ataaagccgactcccgtcgttgccggccttggaaaggtggagcttgagaagataccgggc
ttcggcctcgaagatggacttctcatagggatcgttggaatcactagcaaggagctcggc
ggctctgagctctacgcgaggctcagcataaccgggggaatcgctcccagagtaaacctc
gaagaggagaagacgaacgccgaggggatccttgaggcgatcaagaggggcctcgtgagg
gccgtccacgacgtcagcaagggaggaatagcagtagctctggctgagatggccgttgct
agcagagtcggcttcaccgccgacctctcgaaggttcccgctgaaacctcgaaccccatt
gaggttgccttcagcgagagccacggccgctacatcgttgccttcccagaggaaagcctt
gagaagcttaaggcaatcttcaggcacttcacagtcatcggcagggctgggggaagcgag
gccgtcttcctctggggcaaagaagaactcctgaggaagccagtttccaagcttaaggag
gttcacgagtccctaccaaagctcctgggtgaggaggaatga
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