KEGG   Treponema pallidum subsp. pallidum Nichols: TPANIC_0732
Entry
TPANIC_0732       CDS       T02709                                 
Symbol
folD
Name
(GenBank) bifunctional methylenetetrahydrofolate dehydrogenase (NADP(+))/methenyltetrahydrofolate cyclohydrolase
  KO
K01491  methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
Organism
tpw  Treponema pallidum subsp. pallidum Nichols
Pathway
tpw00670  One carbon pool by folate
tpw00720  Other carbon fixation pathways
tpw01100  Metabolic pathways
tpw01120  Microbial metabolism in diverse environments
tpw01200  Carbon metabolism
tpw01240  Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:tpw00001]
 09100 Metabolism
  09102 Energy metabolism
   00720 Other carbon fixation pathways
    TPANIC_0732 (folD)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    TPANIC_0732 (folD)
Enzymes [BR:tpw01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.5  methylenetetrahydrofolate dehydrogenase (NADP+)
     TPANIC_0732 (folD)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.9  methenyltetrahydrofolate cyclohydrolase
     TPANIC_0732 (folD)
SSDB
Motif
Pfam: THF_DHG_CYH_C THF_DHG_CYH
Other DBs
NCBI-ProteinID: AGN75906
UniProt: O83714
LinkDB
Position
complement(798950..799897)
AA seq 315 aa
MDARLIDGKQAAHECTARLATRVQALRAAVGTAPFLAAVLVGDDPASCTYVAAKQRALAR
AHLRGETHRLPAHASHAQVLELIARLNEDARVHGILIQLPLPAHLDAARVCRAVAPEKDV
DGFHPLNCGALFLAQPGFVPCTPAGIVHLLRRAQVPLAGARVVIVGRSAIVGRPLAVLLA
SPGCDATVTLCHSHTRGLADICVQADILVAALGKARFIGAPFVRTGAVVIDVGIHHVPDA
TAPRGRRLCGDVDFDAVAHKVQAITPVPGGVGPMTIAMLLHNTLCAAEYAAGMIPPFRAA
LYADLDGRAAGDVPH
NT seq 948 nt   +upstreamnt  +downstreamnt
gtggacgcacgcctcatcgatggaaaacaagccgcacacgagtgtacggcgcgtcttgca
acgcgtgtgcaggcgctgcgtgcggcggtaggcacggcgccctttcttgccgcagtgctg
gtgggggatgacccggcttcttgtacctacgttgcagcaaagcagcgtgccctggctcgc
gcccacctgcggggggaaacgcaccggctgcctgctcatgcctctcacgcacaggtgtta
gaacttattgctcgtctcaatgaggacgcgcgggtgcacggcattttgatccaattgccg
ttacctgcgcatcttgacgcagcgagggtgtgccgcgcagtggcgccagaaaaagatgtc
gacggctttcatccgcttaactgtggtgcgctcttccttgcgcagcctgggtttgttccc
tgcacccctgcggggattgtgcacttgctccggcgtgcgcaggtgccgcttgcgggggca
cgcgtggtaattgtcggccgttctgccatcgttggccgtccgcttgcagtgctccttgcc
tctcccggctgtgatgcaaccgtgacgctctgtcacagtcacacgcgcggtttggcggat
atctgtgtgcaggcagatatcctcgttgcagcactgggaaaggcgcgcttcattggcgcg
ccgtttgtgcgcaccggcgccgtggttatcgatgtgggtattcatcacgtgccagatgca
actgcaccgcgcgggagaagactgtgtggtgatgtggattttgacgcagtggcgcacaag
gtgcaggcgatcacgcctgttccggggggagtaggaccgatgactatcgcgatgctgctg
cacaacacgctctgcgctgcagagtatgcagccgggatgatacccccctttagagcggcg
ctctatgccgacctagatggacgcgctgcaggcgacgtaccgcactga

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