Thermacetogenium phaeum: Tph_c05920
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Entry
Tph_c05920 CDS
T02276
Symbol
folC
Name
(GenBank) folylpolyglutamate synthase FolC
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
tpz
Thermacetogenium phaeum
Pathway
tpz00790
Folate biosynthesis
tpz01100
Metabolic pathways
tpz01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
tpz00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
Tph_c05920 (folC)
Enzymes [BR:
tpz01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
Tph_c05920 (folC)
6.3.2.17 tetrahydrofolate synthase
Tph_c05920 (folC)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Radical_SAM_N
Motif
Other DBs
NCBI-ProteinID:
AFV10829
UniProt:
K4LRY4
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All DBs
Position
616448..617773
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AA seq
441 aa
AA seq
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MNYQEALDFLTGLTKFGINFGLERIEHLMSLLGNPERALKVIHVGGTNGKGSTAVMVSRV
LEAAGFRVGLFSSPHLHSYTERYLINHRPISQERFAGLMERLKPLLERMVAEGREHPTEF
EVCTALALLYFFEEKVDYVVLEVGLGGVIDSTNVVPNPLVSVITNVAFDHMDYLGNTITA
IAEKKAGIIKEKGYVVTAAWYPEALAVIEERCREMGATLLRVGKEITWELRESTPEATLF
DLRSPWGFYQNLKVPLAGQYQAVNAATALGVVELLRYRHGVRIGDDHLRQGLAKSRWPAR
LEMISRAPQVIVDVTHNHDGSRMLKNALRNIYRYRRLILVMGMLGDKEREKVVAELAPLA
SVVIITKPLNPRAGDWEKLADEAKRYVEQVFIIEKIAEAVDAALKEASNEDLVCVTGSFY
MVADARAYLLERYFSGAAAGT
NT seq
1326 nt
NT seq
+upstream
nt +downstream
nt
atgaattaccaggaagcactcgattttcttaccggactcacgaaattcggcatcaatttc
ggtctagagcgcattgaacatctgatgagcctgcttgggaatccggagcgggcgctgaag
gtcattcatgtcggggggacgaatgggaaaggttctacggccgtgatggtatcgcgcgtc
ctggaggcggcagggttccgggttgggctcttcagctcccctcacctgcactcctacacc
gagcgctatctgatcaatcaccggcctatctctcaggagcgcttcgccggcctcatggag
cggttgaaaccccttttggagcggatggtggccgaagggcgggagcaccctacggaattc
gaggtctgtaccgccctggccttgctctacttcttcgaggagaaggttgattacgtggtc
ctggaggtcgggctcggaggggttatcgattccaccaatgtggtgccgaaccccctggtc
tccgtaatcaccaatgtggcctttgatcacatggattacctggggaacaccattaccgcc
atcgccgaaaaaaaggcgggcatcattaaagaaaagggttatgtggtgacggcagcctgg
tatccggaggccctggcggtgatcgaggagaggtgccgggagatgggggcaacgctgttg
cgggttggaaaggagataacctgggagctgcgggaatcaacgccggaggccacccttttt
gacttaagaagcccctggggcttctatcaaaatctcaaggtgcctttggcaggacagtac
caggcggtaaatgccgctacggcactgggggttgtcgaactgctgcgctatcgacacggg
gtgagaatcggggacgatcaccttcgacagggtctggcgaaaagccgctggccggcgcgg
ctggagatgatctcccgtgcccctcaggtgatcgtcgatgtcacccacaaccatgacggt
tctcggatgctgaagaatgccctcaggaacatttaccgttaccgcaggctgatcctggtg
atggggatgctgggtgataaggagagagagaaggtggtggccgaactggctcccctggct
tcggttgtgatcattaccaagccgctgaaccctcgcgccggggattgggaaaagctggcc
gatgaggccaagcgctatgtggagcaggtgttcatcatcgagaagatagccgaggcggtg
gatgccgctcttaaagaggcctccaacgaggacctggtctgcgttacgggttctttttat
atggtggcggatgccagggcgtatttgctggagaggtatttttcaggagcagcagctggc
acttga
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