Tardiphaga robiniae: HB776_02125
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Entry
HB776_02125 CDS
T06738
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
trb
Tardiphaga robiniae
Pathway
trb00300
Lysine biosynthesis
trb00550
Peptidoglycan biosynthesis
trb01100
Metabolic pathways
trb01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
trb00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
HB776_02125
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
HB776_02125
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
HB776_02125
Enzymes [BR:
trb01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
HB776_02125
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
QND70168
UniProt:
A0A7G6TTT6
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All DBs
Position
448050..449486
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AA seq
478 aa
AA seq
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MSEFLWTSSAMADAMHATVQGALPEGITGISIDTRTIKSGEAYFAIKGDVHDGHAFVEAA
LKAGAGLAVVEAAQRDKFSADARLLVVDDVLAALVELGIASRARLKAPIVAVTGSVGKTS
TKEALRRVLEAQGKTHASVASFNNHWGVPLTLARCPADVRFAIFEIGMNHAGEIETLVKM
VRPHFAVITTVEPVHLEFFAGVEAIADAKAEIFSGLEPDGVAILNRDNAQFARLQKSAKK
AGVSRIVSFGADQKAEARLLDVSLHPTCSAVHANILGHDVTYKLGMPGRHMAMNSLAVLA
AAELMGADLVHAALTLSQVVPAVGRGARHVLEVPGGEATLIDESYNANPASMAAAINVLG
AAAIGPKGRRIAVLGDMLELGADGAKLHAGLLDAVQSNGIDLVFCCGPLMRNLWDALSTG
KRGGYAGDAAALESQVLAAIRAGDAIMVKGSLGSKMKPIVSALEKRFPGNAALDDAAV
NT seq
1437 nt
NT seq
+upstream
nt +downstream
nt
atgagcgagtttctttggacatcatccgcgatggccgacgcgatgcacgccacggtgcaa
ggcgcgctgccggaaggcatcaccggcatctccatcgatacccgcaccatcaaatccggc
gaggcgtatttcgcgatcaagggcgacgtgcatgacggccacgccttcgtcgaggctgcg
ctgaaagctggcgcaggattggccgtcgtcgaagccgcgcagcgcgacaagttttccgcc
gatgcgcggctgctagtggtcgacgacgtgctcgcagcgctcgtcgaactcggcatcgcc
tcgcgtgcacgtctgaaggcgccaattgtcgctgtcaccggctcggtcggcaagacgtcg
accaaggaagcgctgcgccgcgtgctggaagcgcagggcaagacccatgcctcggtcgcg
tcgttcaacaatcactggggcgtgccgctgacgctggcgcgctgcccggcggacgtgcgc
tttgcgatcttcgaaatcggcatgaaccacgccggtgaaatcgagacgctggtgaagatg
gtgcgaccgcatttcgccgtcatcaccaccgttgagccggtgcatctggaattcttcgct
ggcgtcgaagccattgccgacgccaaggccgaaatcttttcagggcttgaacccgatggc
gtcgcgattctcaaccgcgacaacgcgcagttcgcgcggctgcagaagagcgccaagaag
gcaggtgtctcgcgcatcgtctcgttcggcgccgaccagaaggctgaggcacggctgctc
gacgtctcattgcatccgacctgttcagcggtgcatgccaacattctcggccatgatgtg
acctacaagctcggcatgcccggccgccacatggcgatgaattcgctggcggtgctggcg
gcagccgaattgatgggcgccgatctcgttcatgccgcgctgacgctgtcgcaggtcgtg
cccgctgtgggccgcggcgctcgccatgtgctcgaagtgccaggcggcgaggcgacgctg
attgatgagagctacaatgccaatccggcttcgatggcggccgccatcaatgtactgggc
gctgcggccatcgggccaaagggccgccgcatcgcggtgctcggcgacatgctcgaactc
ggcgccgatggcgcgaaacttcatgccgggttgctggatgcggtgcagtccaacggcatc
gatctggtattttgctgtggtcccctgatgcgcaacctttgggatgccctttccacgggc
aagcggggcggctatgccggggatgcggcggcgctcgaatcgcaggtgctggccgcgatc
cgcgccggtgacgccatcatggtcaagggctcgctcggctcgaagatgaaaccgattgtc
tccgcgctcgaaaagcgctttcccggcaacgccgcgctcgacgacgccgcggtatag
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