Thermocrinis ruber: THERU_06970
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Entry
THERU_06970 CDS
T03001
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K23269
phosphoribosylformylglycinamidine synthase subunit PurL [EC:
6.3.5.3
]
Organism
trd
Thermocrinis ruber
Pathway
trd00230
Purine metabolism
trd01100
Metabolic pathways
trd01110
Biosynthesis of secondary metabolites
Module
trd_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
trd00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
THERU_06970
Enzymes [BR:
trd01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
THERU_06970
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Paralog
GFIT
Motif
Pfam:
AIRS
AIRS_C
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
AHE96451
UniProt:
W0DDN1
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Position
1257808..1260036
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AA seq
742 aa
AA seq
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MEEVYKLYGLTKEEYESIVKRLGREPNHVELGILGALWSEHCSYKSSKRLLKLFPTQGEH
VIQGPGENAGVVKLDDKVWLAFKIESHNHPSFIEPFHGAATGVGGIIRDVLSMGARPIAL
MDSLRFGLPLDSKTKHIVKGVVKGISHYGNSVGIPTVGGETFFEECYKTNPLVNAFCLGI
IPAGRMFRARATKPGQLLFLIGSSTGRDGIHGAVMASGEFSEDTESKRPNVQVGDPYFEK
KLIEALMRIIEEDLVVGIQDLGAAGLAGASSELANKSKMGVVLYLERVPLREEGMNPYEI
LLSESQERMLLVVERDKVQRLKELAKDFHLEGEVVGEMTDDGMFRAYFHGELVAELPVSL
ITEEAPVYERPSREPDYIKQVRSFKEEELEQKDIKDSLLKLLSSPNVCSKEWVYSQYDYQ
VGTNTVLVPGGDAAILRIKWVVSPEIKSEKLVALSCEGNGRMVFLNPYEGGKYVVAEALR
NLACVGAQPLAITDCLNFGNPERPEVMWQLEMAIRGMADACKFFGVPVVSGNVSLYNETV
EEKEIRNIYPTPILVAVGAIEGKRFVTHKFEEEGSLVFLIGDLKRSWGLGGSEYLKVVHG
IVAGDVPAVDLKKEKLLHETLIKLIKEEIILSAHDVSTGGLMIALLECLFGTGLGLELNL
YTEEALDRFFFSESPTRVVVSVEKDKEELLKNYVESVGLDWLYLGKVKGEPELIVKLYEE
PILKENVEDLEKLWRDSLANML
NT seq
2229 nt
NT seq
+upstream
nt +downstream
nt
gtggaggaggtttataagctttacgggctcacgaaggaggaatatgagagtatagtcaaa
aggcttggtagagagccaaaccatgtggaacttggtattcttggtgccctttggtcggag
cattgttcttataaatcttcaaagaggcttttgaagctctttcctacccaaggagagcat
gtaattcagggaccgggggaaaatgcaggcgttgtaaagcttgatgataaagtctggctc
gcctttaagatagaaagccacaatcatccttccttcatagaacccttccacggcgctgcc
acaggtgtgggtgggatcataagggatgtgctctctatgggtgcaagacctatagccttg
atggattctctgcggtttggtttgccactagattcaaagacaaaacacatagtaaaaggc
gtagtaaagggcatatcccactatggcaactcggtgggcattcccacggtgggcggagag
accttttttgaagagtgctacaagaccaaccctctggtgaatgctttttgccttggcata
attcctgcgggcaggatgttccgggcgagggcaacaaaacccggacaactgctcttttta
ataggctcttccactggaagggatggcatacacggtgcggttatggcgtccggtgagttc
agcgaagacacagagagcaaaagacccaacgtgcaggtgggagacccttactttgaaaaa
aagctcatagaagcgctcatgaggataatagaggaagatctggtggtgggtattcaggac
cttggcgccgcgggtcttgcgggtgcatcctccgagctggcaaacaaatccaaaatgggc
gtggtgctataccttgaaagggtgcctctcagagaagagggaatgaacccttatgaaatt
ctcctttctgagagccaagagcgaatgcttttggtggtagaaagggacaaggttcaaagg
ctgaaagaactggcaaaggatttccacttggagggtgaggtggtgggggaaatgaccgat
gatggtatgttccgtgcctacttccacggggagcttgtggcagaactgcccgtaagccta
ataaccgaggaagcacccgtttacgaaagaccaagcagggagcccgattacataaagcag
gttaggtccttcaaagaagaggagttagagcaaaaggacataaaggattcccttcttaag
cttttgtcctctcccaacgtgtgctccaaggagtgggtttacagtcagtatgactatcaa
gtggggacaaacacggtgttggtgccagggggagatgctgcgattctgcgtataaagtgg
gtagtaagcccggagataaaaagcgaaaagctcgtagccttgagctgtgaggggaacggc
aggatggtctttctgaacccttatgaaggcggaaagtacgtagtggcggaagccctcaga
aaccttgcctgtgtgggtgcacagcccttggccataacggattgtctgaactttggaaat
ccagaaaggccggaggtaatgtggcagttggagatggcaataagggggatggcggacgcc
tgcaagttctttggggtgcccgtagtaagcggaaatgtgtccctctacaacgaaacggtg
gaggaaaaggaaatcagaaacatatacccaactcccattttggtggcagtgggtgccata
gaagggaaaaggttcgtaacccacaagtttgaggaggagggtagtttggtctttttgata
ggagacctgaaaagaagctggggcttggggggtagcgaatacttaaaggtggtgcacgga
attgtggctggagatgtgcccgcggtggacctgaagaaagaaaagttactgcatgaaacc
ctaataaagctaataaaagaggaaataattctttctgcccacgatgtatccaccggcgga
cttatgattgccctcttagagtgcctctttggcacgggacttggtctagagctaaacctt
tacaccgaggaagcccttgataggttcttcttctccgaaagtcccacaagggtggtggtt
agcgtagaaaaggataaagaagaacttttgaaaaactatgtggaaagcgtgggattggat
tggctatatttgggtaaagtaaagggtgagccagagcttattgtgaaactctacgaagag
cccatactcaaagagaatgttgaagatctggaaaaactatggagagattctttagccaat
atgctttaa
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